M. Quast, N. Huang, G. Hillman, T. Kent (1993)
The evolution of acute stroke recorded by multimodal magnetic resonance imaging.Magnetic resonance imaging, 11 4
U. Dirnagl (2006)
Bench to Bedside: The Quest for Quality in Experimental Stroke ResearchJournal of Cerebral Blood Flow & Metabolism, 26
M. Cha, Susan Eastwaad, Richard Hartan, D. Maher, I. Olkin, Ray Pitkin, D. Rennie, K. Schulz, D. Simel, Danna Straup (1996)
The CONSORT Statement
Fuhai Li, Sam Han, T. Tatlisumak, Kaiyin Liu, Julio Garcia, C. Sotak, M. Fisher (1999)
Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in ratsAnnals of Neurology, 46
S. Shi, K. Mörike, U. Klotz (2008)
The clinical implications of ageing for rational drug therapyEuropean Journal of Clinical Pharmacology, 64
(2008)
Academic-industrial collaborations: Can academic medicine rescue drug development
L. Goldstein (1998)
Potential effects of common drugs on stroke recovery.Archives of neurology, 55 4
N. Crossley, E. Sena, Jos Goehler, J. Horn, B. Worp, P. Bath, M. Macleod, U. Dirnagl (2008)
Empirical Evidence of Bias in the Design of Experimental Stroke Studies: A Metaepidemiologic ApproachStroke, 39
(1995)
The National Institute of Neurological Disorders and Stroke rt - PA Stroke Study Group , Tissue plasminogen activator for acute ischemic stroke
M. Philip, M. Benatar, M. Fisher, S. Savitz (2009)
Methodological Quality of Animal Studies of Neuroprotective Agents Currently in Phase II/III Acute Ischemic Stroke TrialsStroke, 40
M. Fornage, C. Hinojos, Barbara Nurowska, E. Boerwinkle, B. Hammock, C. Morisseau, P. Doris (2002)
Polymorphism in Soluble Epoxide Hydrolase and Blood Pressure in Spontaneously Hypertensive RatsHypertension: Journal of the American Heart Association, 40
V. O'Collins, M. Macleod, G. Donnan, L. Horky, B. Worp, D. Howells (2006)
1,026 Experimental treatments in acute strokeAnnals of Neurology, 59
A. Walker, J. Nixon (2004)
Improving the quality of reporting in randomised controlled trials.Journal of wound care, 13 3
M. Macleod, M. Fisher, V. O'Collins, V. O'Collins, E. Sena, E. Sena, E. Sena, U. Dirnagl, P. Bath, Alistair Buchan, H. Worp, R. Traystman, K. Minematsu, G. Donnan, G. Donnan, D. Howells, D. Howells (2009)
Reprint: Good Laboratory Practice: Preventing Introduction of Bias at the BenchJournal of Cerebral Blood Flow & Metabolism, 29
G. Courtine, M. Bunge, J. Fawcett, R. Grossman, J. Kaas, R. Lemon, I. Maier, John Martin, R. Nudo, A. Ramón‐cueto, E. Rouiller, L. Schnell, T. Wannier, M. Schwab, R. Edgerton (2007)
Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans?Nature Medicine, 13
B. Hattiangady, M. Rao, A. Shetty (2008)
Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate‐induced injury is lost by middle ageAging Cell, 7
M. Quast, Jingna Wei, N. Huang, D. Brunder, S. Sell, J. González, G. Hillman, T. Kent (1997)
Perfusion Deficit Parallels Exacerbation of Cerebral Ischemia/Reperfusion Injury in Hyperglycemic RatsJournal of Cerebral Blood Flow & Metabolism, 17
J. Zivin, M. Fisher, U. Degirolami, C. Hemenway, J. Stashak (1985)
Tissue plasminogen activator reduces neurological damage after cerebral embolism.Science, 230 4731
D. Altman, K. Schulz, D. Moher, M. Egger, F. Davidoff, D. Elbourne, Peter Gtzsche, Thomas Lang (2001)
The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and ElaborationAnnals of Internal Medicine, 134
E. Lo (2008)
A new penumbra: transitioning from injury into repair after strokeNature Medicine, 14
Sharyl Martini, T. Kent (2007)
Hyperglycemia in Acute Ischemic Stroke: A Vascular PerspectiveJournal of Cerebral Blood Flow & Metabolism, 27
S. Savitz (2007)
A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: A need for more rigorous testing of neuroprotective agents in animal models of strokeExperimental Neurology, 205
J. Simard, T. Kent, Mingkui Chen, K. Tarasov, V. Gerzanich (2007)
Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implicationsThe Lancet Neurology, 6
H. Girouard, C. Iadecola (2006)
Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease.Journal of applied physiology, 100 1
C. Begg, M. Cho, S. Eastwood, Richard Horton, D. Moher, I. Olkin, R. Pitkin, D. Rennie, K. Schulz, D. Simel, D. Stroup (1996)
Improving the quality of reporting of randomized controlled trials. The CONSORT statement.JAMA, 276 8
Stroke Roundtable (1999)
Recommendations for standards regarding preclinical neuroprotective and restorative drug development.Stroke, 30 12
(2007)
Translational medicine perspectives of biomarkers in drug discovery and development: part I target selection and validation—biomarkers take center stage
Byoung Joo Gwag
Askiel Bruno, S. Levine, M. Frankel, T. Brott, Yan-Zu Lin, B. Tilley, P. Lyden, J. Broderick, T. Kwiatkowski, S. Fineberg (2002)
Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke TrialNeurology, 59
P. Hurn, S. Vannucci, H. Hagberg (2005)
Adult or Perinatal Brain Injury: Does Sex Matter?Stroke, 36
W. Kakuda, M. Lansberg, V. Thijs, S. Kemp, R. Bammer, L. Wechsler, M. Moseley, Michael Parks, G. Albers (2008)
Optimal Definition for PWI/DWI Mismatch in Acute Ischemic Stroke PatientsJournal of Cerebral Blood Flow & Metabolism, 28
Alan MacCormack, T. Forbath, P. Brooks, Patrick Kalaher (2007)
Innovation through Global Collaboration: A New Source of Competitive Advantage
N. Henninger, K. Eberius, K. Sicard, R. Kollmar, C. Sommer, S. Schwab, W. Schäbitz (2006)
A new model of thromboembolic stroke in the posterior circulation of the ratJournal of Neuroscience Methods, 156
M. Fisher (2008)
Stroke and TIA: epidemiology, risk factors, and the need for early intervention.The American journal of managed care, 14 6 Suppl 2
J. Grotta, M. Kothari, K. Welch, J. Broderick, B. Tilley, T. Brott, Marler, P. Lyden, P. O'Byrne (1995)
Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group.The New England Journal of Medicine
M. Lindner, V. Gribkoff, Nicole Donlan, T. Jones (2003)
Long-Lasting Functional Disabilities in Middle-Aged Rats with Small Cerebral InfarctsThe Journal of Neuroscience, 23
J. Marshall, R. Cummings, Laura Bowes, R. Ridley (2003)
Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion.Stroke, 34 9
C. Iadecola, R. Davisson (2008)
Hypertension and cerebrovascular dysfunction.Cell metabolism, 7 6
M. Macleod, Tori O'Collins, L. Horky, D. Howells, G. Donnan (2005)
Systematic Review and Metaanalysis of the Efficacy of FK506 in Experimental StrokeJournal of Cerebral Blood Flow & Metabolism, 25
(2007)
The Role of Translational Medicine and Biomarker Research in Drug Discovery and Development
Majaz Moonis; Herbert Moessler
E. Sena, H. Worp, D. Howells, M. Macleod (2007)
How can we improve the pre-clinical development of drugs for stroke?Trends in Neurosciences, 30
M. Macleod, Tori O'Collins, L. Horky, D. Howells, G. Donnan (2005)
Systematic review and metaanalysis of the efficacy of FK 506 in experimental stroke
M. Macleod, H. Worp, E. Sena, E. Sena, D. Howells, U. Dirnagl, G. Donnan (2008)
Evidence for the Efficacy of NXY-059 in Experimental Focal Cerebral Ischaemia Is Confounded by Study QualityStroke, 39
Philip Perera
J. Koziol (2006)
NXY-059 for acute ischemic stroke.The New England journal of medicine, 354 19
H. Worp, E. Sena, G. Donnan, D. Howells, M. Macleod (2007)
Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis.Brain : a journal of neurology, 130 Pt 12
J. Lok, Punkaj Gupta, Shuzhen Guo, W. Kim, M. Whalen, K. Leyen, E. Lo (2007)
Cell–cell Signaling in the Neurovascular UnitNeurochemical Research, 32
Graeme Hankey, J. Spiesser, Zalmai Hakimi, G. Bego, P. Carita, Sylvie Gabriel (2007)
Rate, degree, and predictors of recovery from disability following ischemic strokeNeurology, 68
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Published: Feb 27, 2009
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