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References (99)
-
C. Wylie (1980)
Primordial germ cellsNature, 283
-
E. Gang, J. Jeong, Seung-Hyun Hong, S. Hwang, Seong Kim, I. Yang, Chiyoung Ahn, Hoon Han, Hoeon Kim (2004)
Skeletal Myogenic Differentiation of Mesenchymal Stem Cells Isolated from Human Umbilical Cord BloodSTEM CELLS, 22
-
W. Otto (2002)
Lung epithelial stem cellsThe Journal of Pathology, 197
-
N. Ma, C. Stamm, A. Kaminski, Wenzhong Li, H. Kleine, B. Müller-Hilke, Li Zhang, Y. Ladilov, D. Egger, Prof. Steinhoff (2005)
Human cord blood cells induce angiogenesis following myocardial infarction in NOD/scid-mice.Cardiovascular research, 66 1
-
(2005)
Regulatory networks in embryo-derived pluripotent stem cells -
T. Zwaka, J. Thomson (2005)
A germ cell origin of embryonic stem cells?, 132
-
P. Dyce, Lihua Wen, Julang Li (2006)
In vitro germline potential of stem cells derived from fetal porcine skinNature Cell Biology, 8
-
C. Campli, A. Piscaglia, Luca Pierelli, Sergio Rutella, G. Bonanno, M. Alison, A. Mariotti, Fabio Vecchio, M. Nestola, Giovanni Monego, F. Michetti, S. Mancuso, P. Pola, Giuseppe Leone, G. Gasbarrini, A. Gasbarrini (2004)
A human umbilical cord stem cell rescue therapy in a murine model of toxic liver injury.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 36 9
-
P. Dyce, Hai Zhu, Jesse Craig, Julang Li (2004)
Stem cells with multilineage potential derived from porcine skin.Biochemical and biophysical research communications, 316 3
-
P. Newsome, I. Johannessen, S. Boyle, E. Dalakas, K. McAulay, K. Samuel, F. Rae, L. Forrester, M. Turner, P. Hayes, D. Harrison, W. Bickmore, J. Plevris (2003)
Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion.Gastroenterology, 124 7
-
J. Oosterhuis, L. Looijenga (2005)
Testicular germ-cell tumours in a broader perspectiveNature Reviews Cancer, 5
-
P. Macchiarini, H. Ostertag (2004)
Uncommon primary mediastinal tumours.The Lancet. Oncology, 5 2
-
A Weismann (1885)
The continuity of the germ-plasm as the foundation of a theory of heredity -
B. Pallante, I. Duignan, Daniel Okin, Andrew Chin, Michael Bressan, T. Mikawa, J. Edelberg (2007)
Bone Marrow Oct3/4+ Cells Differentiate Into Cardiac Myocytes via Age-Dependent Paracrine MechanismsCirculation Research, 100
-
F. Lamoury, J. Croitoru‐Lamoury, Bruce Brew (2006)
Undifferentiated mouse mesenchymal stem cells spontaneously express neural and stem cell markers Oct-4 and Rex-1.Cytotherapy, 8 3
-
A. Palermo, Mark LaBarge, R. Doyonnas, J. Pomerantz, H. Blau (2005)
Bone marrow contribution to skeletal muscle: a physiological response to stress.Developmental biology, 279 2
-
R. Carlin, D. Davis, M. Weiss, B. Schultz, D. Troyer (2006)
Expression of early transcription factors Oct-4, Sox-2 and Nanog by porcine umbilical cord (PUC) matrix cellsReproductive Biology and Endocrinology, 4
-
M. Ratajczak, M. Ratajczak, M. Kucia, M. Kucia, R. Reca, Marcin Majka, A. Janowska-Wieczorek, J. Ratajczak (2004)
Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells ‘hide out’ in the bone marrowLeukemia, 18
-
H. Jordan (1917)
The History of the Primordial Germ Cells in the Loggerhead Turtle Embryo.Proceedings of the National Academy of Sciences of the United States of America, 3 4
-
K. Guan, K. Nayernia, L. Maier, S. Wagner, R. Dressel, Jae Lee, J. Nolte, Frieder Wolf, Manyu Li, W. Engel, G. Hasenfuss (2006)
Pluripotency of spermatogonial stem cells from adult mouse testisNature, 440
-
Jiyoung Lee, K. Inoue, R. Ono, N. Ogonuki, T. Kohda, T. Kaneko-Ishino, A. Ogura, F. Ishino (2002)
Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells.Development, 129 8
-
BN Gomperts, JA Belperio, PN Rao, SH Randell, MC Fishbein, MD Burdick (2006)
Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injuryJ Immunol, 176
-
M. Ratajczak, M. Kucia, H. Dobrowolska, J. Wanzeck, R. Reca, J. Ratajczak (2006)
Emerging concept of cancer as a stem cell disorderCentral European Journal of Biology, 1
-
Y. Matsui, K. Zsebo, B. Hogan, M. Obinata (1993)
Derivation of Pluripotential Embryonic Stem Cells from Murine Primordial Germ Cells in Culture.Experimental Animals, 9
-
Mito Kanatsu-Shinohara, K. Inoue, Jiyoung Lee, M. Yoshimoto, N. Ogonuki, H. Miki, Shiro Baba, Takeo Kato, Y. Kazuki, S. Toyokuni, M. Toyoshima, O. Niwa, M. Oshimura, T. Heike, T. Nakahata, F. Ishino, A. Ogura, T. Shinohara (2004)
Generation of Pluripotent Stem Cells from Neonatal Mouse TestisCell, 119
-
P. Coppi, G. Bartsch, M. Siddiqui, Tao Xu, Cesar Santos, L. Perin, G. Mostoslavsky, A. Serre, E. Snyder, J. Yoo, M. Furth, S. Soker, A. Atala (2007)
Isolation of amniotic stem cell lines with potential for therapyNature Biotechnology, 25
-
(1855)
Editorial Archive fuer pathologische -
M. Kucia, B. Dawn, Greg Hunt, Yiru Guo, M. Wysoczynski, M. Majka, J. Ratajczak, F. Rezzoug, S. Ildstad, R. Bolli, M. Ratajczak (2004)
Cells Expressing Early Cardiac Markers Reside in the Bone Marrow and Are Mobilized Into the Peripheral Blood After Myocardial InfarctionCirculation Research, 95
-
F. Tögel, J. Isaac, Zhuma Hu, K. Weiss, C. Westenfelder (2005)
Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury.Kidney international, 67 5
-
Chunfang Liu, Zhongwei Chen, Zhihong Chen, Tao Zhang, Yuan Lu (2006)
Multiple tumor types may originate from bone marrow-derived cells.Neoplasia, 8 9
-
Y. Yamazaki, M. Mann, S. Lee, Joel Marh, J. McCarrey, R. Yanagimachi, M. Bartolomei (2003)
Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloningProceedings of the National Academy of Sciences of the United States of America, 100
-
F. Zeng, Mei-jue Chen, D. Baldwin, Zhi-juan Gong, Jingbin Yan, Hui Qian, Juan Wang, Xiaoyan Jiang, Z. Ren, Deming Sun, Shu‐zhen Huang (2006)
Multiorgan engraftment and differentiation of human cord blood CD34+Lin− cells in goats assessed by gene expression profiling, 103
-
Sandro Francavilla, Sandro Francavilla, Luciano Zamboni, Luciano Zamboni (1985)
Differentiation of mouse ectopic germinal cells in intra- and perigonadal locations.The Journal of experimental zoology, 233 1
-
L. Buzanska, E. Machaj, B. Zabłocka, Z. Pojda, K. Domanska-Janik (2002)
Human cord blood-derived cells attain neuronal and glial features in vitro.Journal of cell science, 115 Pt 10
-
Yue-hua Jiang, B. Jahagirdar, R. Reinhardt, R. Schwartz, C. Keene, X. Ortiz-González, M. Reyes, T. Lenvik, T. Lund, M. Blackstad, J. Du, S. Aldrich, A. Lisberg, W. Low, D. Largaespada, C. Verfaillie (2007)
Pluripotency of mesenchymal stem cells derived from adult marrowNature, 447
-
M. Gomperts, Chris Wylie, J. Heasman (2004)
Primordial germ cell migration.Developmental biology, 2
-
E. Lagasse, Heather Connors, M. Al‐Dhalimy, Michael Reitsma, M. Dohse, L. Osborne, Xin Wang, M. Finegold, I. Weissman, M. Grompe (2000)
Purified hematopoietic stem cells can differentiate into hepatocytes in vivoNature Medicine, 6
-
Joshua Johnson, J. Bagley, M. Skaznik-Wikiel, Ho-Joon Lee, G. Adams, Y. Niikura, Katherine Tschudy, J. Tilly, M. Cortes, R. Forkert, T. Spitzer, J. Iacomini, D. Scadden, J. Tilly (2005)
Oocyte Generation in Adult Mammalian Ovaries by Putative Germ Cells in Bone Marrow and Peripheral BloodCell, 122
-
A. Friedenstein, U. Deriglasova, N. Kulagina, A. Panasuk, S. Rudakowa, E. Luria, I. Ruadkow (1974)
Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method.Experimental hematology, 2 2
-
É. Mezey, K. Chandross, G. Harta, Richard Maki, S. Mckercher (2000)
Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow.Science, 290 5497
-
B. Gomperts, J. Belperio, P. Rao, S. Randell, M. Fishbein, M. Burdick, R. Strieter (2006)
190 CIRCULATING PROGENITOR EPITHELIAL CELLS TRAFFIC VIA CXCR4/CXCL12 IN RESPONSE TO AIRWAY INJURY.Journal of Investigative Medicine, 54
-
M. Felici, Anne McLaren (1983)
In vitro culture of mouse primordial germ cells.Experimental cell research, 144 2
-
G. D’Ippolito, S. Diabira, G. Howard, P. Menei, B. Roos, P. Schiller (2004)
Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potentialJournal of Cell Science, 117
-
T. Ling, M. Kuo, Chung-Leung Li, A. Yu, Yenlin Huang, Tsai-Jung Wu, You-Chin Lin, Shu-Hwa Chen, John Yu (2006)
Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro.Proceedings of the National Academy of Sciences of the United States of America, 103 25
-
Fernando Anjos-Afonso, D. Bonnet (2007)
Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment.Blood, 109 3
-
Edyta Brzóska, I. Grabowska, G. Hoser, W. Stremińska, D. Wasilewska, E. Machaj, Z. Pojda, J. Moraczewski, J. Kawiak (2006)
Participation of stem cells from human cord blood in skeletal muscle regeneration of SCID mice.Experimental hematology, 34 9
-
D. Colter, I. Sekiya, D. Prockop (2001)
Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cellsProceedings of the National Academy of Sciences of the United States of America, 98
-
G. Martin (1981)
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.Proceedings of the National Academy of Sciences of the United States of America, 78 12
-
B. Petersen, W. Bowen, K. Patrene, W. Mars, A. Sullivan, N. Murase, S. Boggs, J. Greenberger, J. Goff (1999)
Bone marrow as a potential source of hepatic oval cells.Science, 284 5417
-
T. Muramatsu, H. Muramatsu (2004)
Carbohydrate antigens expressed on stem cells and early embryonic cellsGlycoconjugate Journal, 21
-
F. Barr (1997)
Molecular Genetics and Pathogenesis of RhabdomyosarcomaJournal of Pediatric Hematology/Oncology, 19
-
A. McLaren (2003)
Primordial germ cells in the mouse.Developmental biology, 262 1
-
RJ Henning, H Abu-Ali, JU Balis, MB Morgan, AE Willing, PR Sanberg (2004)
Human umbilical cord blood mononuclear cells for the treatment of acute myocardial infarctionCell Transplant, 13
-
(2004)
Mobilization of CD 34 / CXCR 4 , CD 34 / CD 117 , c-met Stem Cells , and Mononuclear Cells Expressing Early Cardiac , Muscle , and Endothelial Markers Into Peripheral Blood in Patients With Acute Myocardial Infarction -
Yang Li, R. Reca, P. Atmaca-Sonmez, M. Ratajczak, S. Ildstad, H. Kaplan, V. Enzmann (2006)
Retinal pigment epithelium damage enhances expression of chemoattractants and migration of bone marrow-derived stem cells.Investigative ophthalmology & visual science, 47 4
-
M. Kucia, M. Hałasa, M. Wysoczynski, M. Baśkiewicz‐Masiuk, S. Moldenhawer, E. Zuba-Surma, R. Czajka, W. Wojakowski, B. Machaliński, M. Ratajczak (2007)
Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood – preliminary reportLeukemia, 21
-
C. McGuckin, N. Forraz, M. Baradez, S. Navran, J. Zhao, R. Urban, R. Tilton, Larry Denner (2005)
Production of stem cells with embryonic characteristics from human umbilical cord bloodCell Proliferation, 38
-
J. Thomson, J. Kalishman, T. Golos, M. Durning, C. Harris, Robert Becker, J. Hearn (1995)
Isolation of a primate embryonic stem cell line.Proceedings of the National Academy of Sciences of the United States of America, 92 17
-
P. Donovan (1998)
The germ cell--the mother of all stem cells.The International journal of developmental biology, 42 7
-
S. Danner, Jennifer Kajahn, C. Geismann, E. Klink, C. Kruse (2007)
Derivation of oocyte-like cells from a clonal pancreatic stem cell line.Molecular human reproduction, 13 1
-
J. Mann (2001)
Imprinting in the Germ LineSTEM CELLS, 19
-
M. Evans, M. Kaufman (1981)
Establishment in culture of pluripotential cells from mouse embryosNature, 292
-
M. Kucia, R. Reca, V. Jala, Buddhadeb Dawn, J. Ratajczak, M. Ratajczak (2005)
Bone marrow as a home of heterogenous populations of nonhematopoietic stem cellsLeukemia, 19
-
Y. Matsui, K. Zsebo, B. Hogan (1992)
Derivation of pluripotential embryonic stem cells from murine primordial germ cells in cultureCell, 70
-
Hong Yu, D. Fang, Suresh Kumar, Ling Li, Thiennga Nguyen, G. Acs, M. Herlyn, Xiaowei Xu (2006)
Isolation of a novel population of multipotent adult stem cells from human hair follicles.The American journal of pathology, 168 6
-
D. Krause, N. Theise, M. Collector, O. Henegariu, Sonya Hwang, Rebekah Gardner, S. Neutzel, S. Sharkis (2001)
Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem CellCell, 105
-
K. Mitsui, Yoshimi Tokuzawa, Hiroaki Itoh, K. Segawa, M. Murakami, Kazutoshi Takahashi, Masayoshi Maruyama, M. Maeda, S. Yamanaka (2003)
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES CellsCell, 113
-
M. Shamblott, J. Axelman, Shunping Wang, E. Bugg, J. Littlefield, P. Donovan, P. Blumenthal, G. Huggins, J. Gearhart (1998)
Derivation of pluripotent stem cells from cultured human primordial germ cells.Proceedings of the National Academy of Sciences of the United States of America, 95 23
-
Mark LaBarge, H. Blau (2002)
Biological Progression from Adult Bone Marrow to Mononucleate Muscle Stem Cell to Multinucleate Muscle Fiber in Response to InjuryCell, 111
-
Tomono Takahashi, C. Kalka, H. Masuda, Donghui Chen, Marcy Silver, M. Kearney, M. Magner, J. Isner, T. Asahara (1999)
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularizationNature Medicine, 5
-
H. Niwa, J. Miyazaki, Austin Smith (2000)
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsNature Genetics, 24
-
R. Pochampally, Jason Smith, Joni Ylostalo, D. Prockop (2004)
Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes.Blood, 103 5
-
W. Shyu, Shinn-Zong Lin, Hui-I Yang, Yi-shiuan Tzeng, Cheng-Yoong Pang, P. Yen, Hung Li (2004)
Functional Recovery of Stroke Rats Induced by Granulocyte Colony-Stimulating Factor–Stimulated Stem CellsCirculation, 110
-
D. Hay, Linda Sutherland, John Clark, T. Burdon (2004)
Oct‐4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in Human and Mouse Embryonic Stem CellsSTEM CELLS, 22
-
P. Andrews, M. Matin, A. Bahrami, I. Damjanov, P. Gokhale, J. Draper (2005)
Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin.Biochemical Society transactions, 33 Pt 6
-
J. Houghton, C. Stoicov, S. Nomura, A. Rogers, J. Carlson, Hanchen Li, Xun Cai, J. Fox, J. Goldenring, T. Wang (2004)
Gastric Cancer Originating from Bone Marrow-Derived CellsScience, 306
-
Yong Zhao, Honglan Wang, T. Mazzone (2006)
Identification of stem cells from human umbilical cord blood with embryonic and hematopoietic characteristics.Experimental cell research, 312 13
-
C. Kruse, Jennifer Kajahn, A. Petschnik, A. Maass, E. Klink, D. Rapoport, T. Wedel (2006)
Adult pancreatic stem/progenitor cells spontaneously differentiate in vitro into multiple cell lineages and form teratoma-like structures.Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 188 6
-
Hideto Koso, Yasuo Ouchi, Yoko Tabata, Yutaka Aoki, Shinya Satoh, K. Arai, Sumiko Watanabe (2006)
SSEA-1 marks regionally restricted immature subpopulations of embryonic retinal progenitor cells that are regulated by the Wnt signaling pathway.Developmental biology, 292 1
-
M. Kucia, Yonghui Zhang, R. Reca, M. Wysoczynski, B. Machaliński, B. Machaliński, M. Majka, M. Majka, S. Ildstad, J. Ratajczak, C. Shields, M. Ratajczak, M. Ratajczak (2006)
Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following strokeLeukemia, 20
-
Anne McLaren (2009)
Development of primordial germ cells in the mouse *Andrologia, 24
-
N. Baal, K. Reisinger, H. Jahr, R. Bohle, O. Liang, K. Münstedt, C. Rao, K. Preissner, M. Zygmunt (2004)
Expression of transcription factor Oct-4 and other embryonic genes in CD133 positive cells from human umbilical cord bloodThrombosis and Haemostasis, 92
-
M. Ratajczak, E. Zuba-Surma, M. Kucia, R. Reca, W. Wojakowski, J. Ratajczak (2006)
The pleiotropic effects of the SDF-1–CXCR4 axis in organogenesis, regeneration and tumorigenesisLeukemia, 20
-
J. Rossant, Virginia Papaioannou (1984)
The relationship between embryonic, embryonal carcinoma and embryo-derived stem cells.Cell differentiation, 15 2-4
-
L. Turnpenny, S. Brickwood, C. Spalluto, K. Piper, I. Cameron, David Wilson, N. Hanley (2003)
Derivation of Human Embryonic Germ Cells: An Alternative Source of Pluripotent Stem CellsSTEM CELLS, 21
-
By Friedenstein, I. Piatetzky-Shapiro, K. Petrakova (1966)
Osteogenesis in transplants of bone marrow cells.Journal of embryology and experimental morphology, 16 3
-
M. Kucia, B. Machaliński, M. Ratajczak (2006)
The developmental deposition of epiblast/germ cell-line derived cells in various organs as a hypothetical explanation of stem cell plasticity?Acta neurobiologiae experimentalis, 66 4
-
Lepeng Zeng, E. Rahrmann, Qingsong Hu, T. Lund, Lee Sandquist, Mike Felten, T. O’Brien, Jianyi(Jay) Zhang, C. Verfaillie (2006)
Multipotent Adult Progenitor Cells from Swine Bone MarrowSTEM CELLS, 24
-
S. Kakinuma, Yujiro Tanaka, Ryoko Chinzei, Mamoru Watanabe, K. Shimizu‐saito, Y. Hara, K. Teramoto, S. Arii, C. Sato, K. Takase, T. Yasumizu, H. Teraoka (2003)
Human Umbilical Cord Blood as a Source of Transplantable Hepatic Progenitor CellsSTEM CELLS, 21
-
G. Kögler, Sandra Sensken, J. Airey, T. Trapp, M. Müschen, N. Feldhahn, S. Liedtke, R. Sorg, J. Fischer, C. Rosenbaum, Susanne Greschat, A. Knipper, J. Bender, Ö. Degistirici, Jizong Gao, A. Caplan, E. Colletti, G. Almeida-Porada, H. Müller, E. Zanjani, P. Wernet (2004)
A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation PotentialThe Journal of Experimental Medicine, 200
-
K. Nayernia, Jae Lee, Nadja Drusenheimer, J. Nolte, G. Wulf, R. Dressel, J. Gromoll, W. Engel (2006)
Derivation of male germ cells from bone marrow stem cellsLaboratory Investigation, 86
-
S. Devine, N. Flomenberg, D. Vesole, J. Liesveld, D. Weisdorf, K. Badel, G. Calandra, J. Dipersio (2004)
Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22 6
-
M. Amit, M. Carpenter, M. Inokuma, C. Chiu, C. Harris, M. Waknitz, J. Itskovitz‐Eldor, J. Thomson (2000)
Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture.Developmental biology, 227 2
-
R. Lemoli, L. Catani, S. Talarico, E. Loggi, A. Gramenzi, U. Baccarani, M. Fogli, G. Grazi, M. Aluigi, G. Marzocchi, M. Bernardi, A. Pinna, F. Bresadola, M. Baccarani, P. Andreone (2006)
Mobilization of Bone Marrow‐Derived Hematopoietic and Endothelial Stem Cells After Orthotopic Liver Transplantation and Liver ResectionSTEM CELLS, 24
-
S. Corbel, Adrienne Lee, L. Yi, J. Duenas, T. Brazelton, H. Blau, F. Rossi (2003)
Contribution of hematopoietic stem cells to skeletal muscleNature Medicine, 9
-
G. Eghbali-Fatourechi, J. Lamsam, Daniel Fraser, D. Nagel, B. Riggs, S. Khosla (2005)
Circulating osteoblast-lineage cells in humans.The New England journal of medicine, 352 19
-
S. Upadhyay, L. Zamboni (1982)
Ectopic germ cells: natural model for the study of germ cell sexual differentiation.Proceedings of the National Academy of Sciences of the United States of America, 79 21
-
M. Kucia, R. Reca, F. Campbell, E. Zuba-Surma, M. Majka, J. Ratajczak, M. Ratajczak (2006)
A population of very small embryonic-like (VSEL) CXCR4+SSEA-1+Oct-4+ stem cells identified in adult bone marrowLeukemia, 20
-
W. Wojakowski, M. Tendera, A. Michałowska, M. Majka, M. Kucia, K. Maślankiewicz, Rafał Wyderka, A. Ochała, M. Ratajczak (2004)
Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ Stem Cells, and Mononuclear Cells Expressing Early Cardiac, Muscle, and Endothelial Markers Into Peripheral Blood in Patients With Acute Myocardial InfarctionCirculation, 110
- Publisher
- Springer Journals
- Copyright
- Copyright © 2007 by Nature Publishing Group
- Subject
- Medicine & Public Health; Medicine/Public Health, general; Internal Medicine; Intensive / Critical Care Medicine; Cancer Research; Oncology; Hematology
- ISSN
- 0887-6924
- eISSN
- 1476-5551
- DOI
- 10.1038/sj.leu.2404630
- Publisher site
- See Article on Publisher Site
Abstract
Accumulating evidence demonstrates that adult tissues contain a population of stem cells that express early developmental markers such as stage-specific embryonic antigen and transcription factors Oct-4 and Nanog. These are the markers characteristic for embryonic stem cells, epiblast stem cells and primordial germ cells. The presence of these stem cells in adult tissues including bone marrow, epidermis, bronchial epithelium, myocardium, pancreas and testes supports the concept that adult tissues contain some population of pluripotent stem cells that is deposited in embryogenesis during early gastrulation. In this review we will discuss these data and present a hypothesis that these cells could be direct descendants of the germ lineage. The germ lineage in order to pass genes on to the next generations creates soma and thus becomes a ‘mother lineage’ for all somatic cell lineages present in the adult body.
Journal
Leukemia – Springer Journals
Published: Mar 8, 2007