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References (123)
-
C. Jordan, B. Watkins, Conrad Kufta, M. Dubois‐Dalcq, H. Dorn, W. Kelly (1991)
Infection of brain microglial cells by human immunodeficiency virus type 1 is CD4 dependentJournal of Virology, 65
-
B. Brew, M. Rosenblum, K. Cronin, R. Price (1995)
AIDS dementia complex and HIV‐1 brain infection: Clinical‐virological correlationsAnnals of Neurology, 38
-
E. Masliah, N. Ge, M. Morey, R. DeTeresa, R. Terry, C. Wiley (1992)
Cortical dendritic pathology in human immunodeficiency virus encephalitis.Laboratory investigation; a journal of technical methods and pathology, 66 3
-
M. Hartmann, T. Clark, R. Eldik (1996)
Investigation of the Uncatalyzed Hydration of CO2 and First Approximations to the Active Site of Carbonic Anhydrase - A Combined Ab initio and DFT Study -Molecular modeling annual, 2
-
Douglas McDonald, K. Brunden, G. Landreth (1997)
Amyloid Fibrils Activate Tyrosine Kinase-Dependent Signaling and Superoxide Production in MicrogliaThe Journal of Neuroscience, 17
-
M. Tardieu, N. Janabi (1994)
HIV-1 and the developing human nervous system: in vivo and in vitro aspects.Developmental neuroscience, 16 3-4
-
L. Bö, S. Mörk, P. Kong, H. Nyland, C. Pardo, B. Trapp (1994)
Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesionsJournal of Neuroimmunology, 51
-
D. Selkoe (1996)
Cell biology of the beta-amyloid precursor protein and the genetics of Alzheimer's disease.Cold Spring Harbor symposia on quantitative biology, 61
-
M. Goedert, M. Spillantini, M. Hasegawa, R. Jakes, R. Crowther, A. Klug (1995)
Molecular dissection of the neurofibrillary lesions of Alzheimer's disease.Cold Spring Harbor symposia on quantitative biology, 61
-
W. Rinner, J. Bauer, J. Bauer, M. Schmidts, H. Lassmann, H. Lassmann, W. Hickey (1995)
Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune transferred experimental autoimmune encephalomyelitis: An investigation using rat radiation bone marrow chimerasGlia, 14
-
L. Meda, M. Cassatella, G. Szendrei, L. Otvos, P. Baron, M. Villalba, D. Ferrari, F. Rossi (1995)
Activation of microglial cells by β-amyloid protein and interferon-γNature, 374
-
M. Ard, G. Cole, J. Wei, A. Mehrle, J. Fratkin (1996)
Scavenging of Alzheimer's amyloid β‐protein by microglia in cultureJournal of Neuroscience Research, 43
-
J. Glass, S. Wesselingh, O. Selnes, J. McArthur (1993)
Clinical‐neuropathologic correlation in HIV‐associated dementiaNeurology, 43
-
S. Westmoreland, D. Kolson, F. González-Scarano (1996)
Toxicity of TNF alpha and platelet activating factor for human NT2N neurons: a tissue culture model for human immunodeficiency virus dementia.Journal of neurovirology, 2 2
-
K. Kondo, H. Hashimoto, J. Kitanaka, M. Sawada, A. Suzumura, T. Marunouchi, A. Baba (1995)
Expression of glutamate transporters in cultured glial cellsNeuroscience Letters, 188
-
L. Perlmutter, S. Scott, E. Barrón, H. Chui (1992)
MHC class II‐positive microglia in human brain: Association with alzheimer lesionsJournal of Neuroscience Research, 33
-
S. Peudenier, C. Héry, K.Heng Ng, Marc Tardieu (1991)
HIV receptors within the brain: a study of CD4 and MHC-II on human neurons, astrocytes and microglial cells.Research in virology, 142 2-3
-
E. Hughes, J. Bell, P. Simmonds (1997)
Investigation of the dynamics of the spread of human immunodeficiency virus to brain and other tissues by evolutionary analysis of sequences from the p17gag and env genesJournal of Virology, 71
-
J. Glass, H. Fedor, S. Wesselingh, J. McArthur (1995)
Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementiaAnnals of Neurology, 38
-
J. Sabatier, E. Vivés, K. Mabrouk, A. Benjouad, H. Rochat, A. Duval, B. Hue, E. Bahraoui (1991)
Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1Journal of Virology, 65
-
Donata Paresce, H. Chung, F. Maxfield (1997)
Slow Degradation of Aggregates of the Alzheimer’s Disease Amyloid β-Protein by Microglial Cells*The Journal of Biological Chemistry, 272
-
G. Nuovo, M. Alfieri, A. Cerami (1996)
AIDS Dementia Is Associated with Massive, Activated HIV-1 Infection and Concomitant Expression of Several CytokinesMolecular Medicine, 2
-
S. Barnum, Jennifer Jones, E. Benveniste (1993)
Interleukin‐1 and tumor necrosis factor‐mediated regulation of C3 gene expression in human astroglioma cellsGlia, 7
-
D. Sharma, M. Zink, M. Anderson, R. Adams, J. Clements, S. Joag, O. Narayan (1992)
Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocytetropic parental virus: pathogenesis of infection in macaquesJournal of Virology, 66
-
P. Bachwich, S. Chensue, J. Larrick, S. Kunkel (1986)
Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages.Biochemical and biophysical research communications, 136 1
-
S. Wesselingh, Kiyomi Takahashi, J. Glass, J. McArthur, J. Griffin, D. Griffin (1997)
Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistryJournal of Neuroimmunology, 74
-
Susan Westmoreland, J. Rottman, Kenneth Williams, Andrew Lackner, Vito Sasseville (1998)
Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis.The American journal of pathology, 152 3
-
A. Korotzer, J. Watt, D. Cribbs, A. Tenner, D. Burdick, C. Glabe, C. Cotman (1995)
Cultured Rat Microglia Express C1q and Receptor for C1q: Implications for Amyloid Effects on MicrogliaExperimental Neurology, 134
-
C. Wiley, R. Schrier, J. Nelson, P. Lampert, M. Oldstone (1986)
Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.Proceedings of the National Academy of Sciences of the United States of America, 83 18
-
A. Diop, M. Lesort, F. Esclaire, P. Sindou, P. Couratier, J. Hugon (1994)
Tetrodotoxin blocks HIV coat protein (gp120) toxicity in primary neuronal culturesNeuroscience Letters, 165
-
J. Davis, H. McMurray, D. Schubert (1992)
The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes.Biochemical and biophysical research communications, 189 2
-
H. Gelbard, H. Nottet, S. Swindells, M. Jett, K. Dzenko, P. Genis, R. White, L. Wang, Y. Choi, Dongxian Zhang (1994)
Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxinJournal of Virology, 68
-
J. Rottman, K. Ganley, Kenneth Williams, Lijun Wu, C. Mackay, D. Ringler (1997)
Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.The American journal of pathology, 151 5
-
K. Akassoglou, L. Probert, G. Kontogeorgos, G. Kollias (1997)
Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice.Journal of immunology, 158 1
-
E. Stephens, Z. Liu, G. Zhu, I. Adany, S. Joag, L. Foresman, N. Berman, O. Narayan (1995)
Lymphocyte-tropic simian immunodeficiency virus causes persistent infection in the brains of rhesus monkeys.Virology, 213 2
-
B. Yankner, L. Dawes, Shannon Fisher, L. Villa-komaroff, M. Oster-Granite, R. Neve (1989)
Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease.Science, 245 4916
-
S. Ilschner, C. Ohlemeyer, G. Gimpl, Helmut Kettenmann (1995)
Modulation of potassium currents in cultured murine microglial cells by receptor activation and intracellular pathwaysNeuroscience, 66
-
A. Dumuis, M. Sebben, L. Haynes, J. Pin, J. Bockaert (1988)
NMDA receptors activate the arachidonic acid cascade system in striatal neuronsNature, 336
-
Jianglin He, You-zhi Chen, M. Farzan, H. Choe, A. Ohagen, S. Gartner, J. Busciglio, Xiaoyu Yang, W. Hofmann, W. Newman, C. Mackay, J. Sodroski, D. Gabuzda (1997)
CCR3 and CCR5 are co-receptors for HIV-1 infection of microgliaNature, 385
-
Marcel Verbeek, D. Ruiter, R. Waal (1997)
The role of amyloid in the pathogenesis of Alzheimer's disease.Biological chemistry, 378 9
-
Yu Feng, C. Broder, P. Kennedy, E. Berger (1996)
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorScience, 272
-
Clayton Wiley, Cristian Achim (1994)
Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndromeAnnals of Neurology, 36
-
R. Banati, D. Hoppe, K. Gottmann, G. Kreutzberg, H. Kettenmann (1991)
A subpopulation of bone marrow‐derived macrophage‐like cells shares a unique ion channel pattern with microgliaJournal of Neuroscience Research, 30
-
Subramaniam Sriram, Moses Rodriguez (1997)
Indictment of the microglia as the villain in multiple sclerosisNeurology, 48
-
P. Mcgeer, M. Schulzer, E. Mcgeer (1996)
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's diseaseNeurology, 47
-
R. Brinkmann, A. Schwinn, O. Narayan, C. Zink, H. Kreth, W. Roggendorf, R. Dörries, S. Schwender, H. Imrich, V. Meulen (1992)
Human immunodeficiency virus infection in microglia: Correlation between cells infected in the brain and cells cultured from infectious brain tissueAnnals of Neurology, 31
-
S. Wilt, E. Milward, Jia Zhou, K. Nagasato, Heather Patton, R. Rusten, D. Griffin, Michael O'Connor, M. Dubois‐Dalcq (1995)
In vitro evidence for a dual role of tumor necrosis factor‐α in human immunodeficiency virus type 1 encephalopathyAnnals of Neurology, 37
-
E. Lavi, J. Strizki, Anthony Ulrich, Wei Zhang, L. Fu, Qian Wang, M. O'Connor, M. O'Connor, J. Hoxie, F. González-Scarano (1997)
CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons.The American journal of pathology, 151 4
-
F. Chaudhry, K. Lehre, M. Campagne, O. Ottersen, N. Danbolt, J. Storm-Mathisen (1995)
Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistryNeuron, 15
-
H. Akiyama, I. Tooyama, T. Kawamata, K. Ikeda, P. Mcgeer (1993)
Morphological diversities of CD44 positive astrocytes in the cerebral cortex of normal subjects and patients with Alzheimer's diseaseBrain Research, 632
-
O. Bagasra, E. Lavi, L. Bobroski, K. Khalili, J. Pestaner, R. Tawadros, R. Pomerantz (1996)
Cellular reservoirs of HIV‐1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistryAIDS, 10
-
W. Hickey, K. Vass, H. Lassmann (1992)
Bone Marrow-derived Elements in the Central Nervous System: An Immunohistochemical and Ultrastructural Survey of Rat ChimerasJournal of Neuropathology and Experimental Neurology, 51
-
Jun Liu, M. Zhao, C. Brosnan, S. Lee (1996)
Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist.Journal of immunology, 157 8
-
S. Toggas, E. Masliah, E. Rockenstein, Glenn Rail, C. Abraham, L. Mucke (1994)
Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic miceNature, 367
-
P. Tienari, B. Strooper, E. Ikonen, N. Ida, M. Simons, C. Masters, C. Dotti, K. Beyreuther (1996)
Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease.Cold Spring Harbor symposia on quantitative biology, 61
-
A. Sasaki, H. Yamaguchi, A. Ogawa, S. Sugihara, Y. Nakazato (1997)
Microglial activation in early stages of amyloid β protein depositionActa Neuropathologica, 94
-
Thomas, Wisniewski, E. Castaño, A. Golabek, T. Vogel, B. Frangione (1994)
Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro.The American journal of pathology, 145 5
-
Christopher Power, J. Mcarthur, Richard Johnson, D. Griffin, Jonathan Glass, S. Perryman, Bruce Chesebro (1994)
Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequencesJournal of Virology, 68
-
J. Rogers, L. Kirby, S. Hempelman, D. Berry, P. Mcgeer, A. Kaszniak, J. Zalinski, M. Cofield, L. Mansukhani, P. Willson, F. Kogan (1993)
Clinical trial of indomethacin in Alzheimer's diseaseNeurology, 43
-
Eric Berthiaume, Clifford Medina, Joel Swanson (1995)
Molecular size-fractionation during endocytosis in macrophagesThe Journal of Cell Biology, 129
-
A. Richardson, C. Hao, S. Fedoroff (1993)
Microglia progenitor cells: A subpopulation in cultures of mouse neopallial astrogliaGlia, 7
-
P. Gallo, M. Piccinno, L. Krźalić, B. Tavolato (1989)
Tumor necrosis factor alpha (TNFα) and neurological diseases Failure in detecting TNFα in the cerebrospinal fluid from patients with multiple sclerosis, AIDS dementia complex, and brain tumoursJournal of Neuroimmunology, 23
-
D. Giulian, L. Haverkamp, Jia-ping Yu, W. Karshin, D. Tom, Jun Li, J. Kirkpatrick, Y. Kuo, A. Roher (1996)
Specific Domains of β-Amyloid from Alzheimer Plaque Elicit Neuron Killing in Human MicrogliaThe Journal of Neuroscience, 16
-
J. Rogers, N. Cooper, S. Webster, J. Schultz, P. Mcgeer, S. Styren, W. Civin, L. Brachova, B. Bradt, P. Ward (1992)
Complement activation by beta-amyloid in Alzheimer disease.Proceedings of the National Academy of Sciences of the United States of America, 89 21
-
T. Dragic, V. Litwin, G. Allaway, S. Martin, Yaoxing Huang, K. Nagashima, C. Cayanan, P. Maddon, R. Koup, J. Moore, W. Paxton (1996)
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Nature, 381
-
Saumya Das, H. Potter (1995)
Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1Neuron, 14
-
S. Barger, A. Harmon (1997)
Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein ENature, 388
-
E. Ulvestad, K. Williams, C. Vedeler, J. Antel, H. Nyland, S. Mørk, R. Matre (1994)
Reactive microglia in multiple sclerosis lesions have an increased expression of receptors for the Fc part of IgGJournal of the Neurological Sciences, 121
-
D. Griffin, S. Wesselingh, J. McArthur (1994)
Elevated central nervous system prostaglandins in human immunodeficiency virus—associated dementiaAnnals of Neurology, 35
-
B. Doranz, J. Rucker, Y. Yi, R. Smyth, M. Samson, S. Peiper, M. Parmentier, R. Collman, R. Doms (1996)
A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion CofactorsCell, 85
-
D. Giulian, L. Haverkamp, Jun Li, W. Karshin, Jenny Yu, D. Tom, Xia Li, J. Kirkpatrick (1995)
Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brainNeurochemistry International, 27
-
E. Jordan, M. Heyes (1993)
Virus isolation and quinolinic acid in primary and chronic simian immunodeficiency virus infectionAIDS, 7
-
M. Mattson, B. Cheng, A. Culwell, F. Esch, I. Lieberburg, R. Rydel (1993)
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor proteinNeuron, 10
-
L. Sharer (1992)
Pathology of HIV‐1 Infection of the Central Nervous System. A reviewJournal of Neuropathology and Experimental Neurology, 51
-
R. Kalaria, George Perry (1993)
Amyloid P component and other acute-phase proteins associated with cerebellar Aβ-deposits in Alzheimer's diseaseBrain Research, 631
-
W. Tyor, J. Glass, J. Griffin, P. Becker, J. McArthur, L. Bezman, D. Griffin (1992)
Cytokine expression in the brain during the acquired immunodeficiency syndromeAnnals of Neurology, 31
-
H. Lassmann, M. Schmied, K. Vass, W. Hickey (1993)
Bone marrow derived elements and resident microglia in brain inflammationGlia, 7
-
N. Peress, H. Fleit, E. Perillo, R. Kuljiš, C. Pezzullo (1993)
Identification of FcγRI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's diseaseJournal of Neuroimmunology, 48
-
D. Kolson, J. Buchhalter, R. Collman, B. Hellmig, Catherine Farrell, C. Debouck, F. González-Scarano (1993)
HIV-1 Tat alters normal organization of neurons and astrocytes in primary rodent brain cell cultures: RGD sequence dependence.AIDS research and human retroviruses, 9 7
-
J. Mankowski, J. Spelman, H Ressetar, J Strandberg, J. Laterra, D. Carter, J Clements, M. Zink (1994)
Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitroJournal of Virology, 68
-
G. Nuovo, F. Gallery, P. MacConnell, A. Braun (1994)
In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system.The American journal of pathology, 144 4
-
T. Lane, M. Buchmeier, D. Watry, D. Jakubowski, H. Fox (1995)
Serial passage of microglial SIV results in selection of homogeneous env quasispecies in the brain.Virology, 212 2
-
L. Bitting, A. Naidu, B. Cordell, G. Murphy (1996)
β-Amyloid Peptide Secretion by a Microglial Cell Line Is Induced by β-Amyloid-(25–35) and Lipopolysaccharide*The Journal of Biological Chemistry, 271
-
R. Banati, J. Gehrmann, P. Schubert, G. Kreutzberg (1992)
Cytotoxicity of microgliaJournal of Neuroimmunology, 40
-
D. Seilhean, Kasutji Kobayashi, Y. He, T. Uchihara, O. Rosenblum, C. Katlama, F. Bricaire, C. Duyckaerts, J. Hauw (1997)
Tumor necrosis factor-α, microglia and astrocytes in AIDS dementia complexActa Neuropathologica, 93
-
P. Mcgeer, S. Itagaki, H. Tago, E. Mcgeer (1987)
Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DRNeuroscience Letters, 79
-
S. Lipton (1996)
Similarity of Neuronal Cell Injury and Death in AIDS Dementia and Focal Cerebral Ischemia: Potential Treatment with NMDA Open‐Channel Blockers and Nitric Oxide‐Related SpeciesBrain Pathology, 6
-
Cristian Achim, M. Heyes, Clayton Wiley (1993)
Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains.The Journal of clinical investigation, 91 6
-
Masayuki Ii, M. Sunamoto, K. Ohnishi, Y. Ichimori (1996)
β-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicityBrain Research, 720
-
T. Murphy, A. Parikh, R. Schnaar, J. Coyle (1989)
Arachidonic Acid Metabolism in Glutamate NeurotoxicityAnnals of the New York Academy of Sciences, 559
-
U. Müller-Ladner, Jennifer Jones, R. Wetsel, S. Gay, C. Raine, S. Barnum (1996)
Enhanced expression of chemotactic receptors in multiple sclerosis lesionsJournal of the Neurological Sciences, 144
-
D. Dickson, Sunhee Lee, L. Mattiace, S. Yen, C. Brosnan (1993)
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's diseaseGlia, 7
-
D. Brenneman, G. Westbrook, S. Fitzgerald, D. Ennist, K. Elkins, M. Ruff, C. Pert (1988)
Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptideNature, 335
-
E. Ulvestad, K. Williams, R. Matre, H. Nyland, A. Olivier, J. Antel (1994)
Fc Receptors for IgG on Cultured Human Microglia Mediate Cytotoxicity and Phagocytosis of Antibody-coated TargetsJournal of Neuropathology and Experimental Neurology, 53
-
D. Giulian, Elaine Wendt, Ken Vaca, A. Christine, Noonano (1993)
The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes.Proceedings of the National Academy of Sciences of the United States of America, 90 7
-
J. Blass, Bk Ko, H. Wisniewski (1991)
Pathology of Alzheimer's disease.The Psychiatric clinics of North America, 14 2
-
Joan Lane, V. Sasseville, Mary Smith, Peter Vogel, D. Pauley, M. Heyes, Andrew Lackner (1996)
Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation.Journal of neurovirology, 2 6
-
W. Griffin, J. Sheng, G. Roberts, R. Mrak (1995)
Interleukin‐1 Expression in Different Plaque Types in Alzheimer's Disease: Significance in Plaque EvalutionJournal of Neuropathology and Experimental Neurology, 54
-
A. Horita (1992)
SOME BIOCHEMICAL STUDIES ON PSILOCYBIN AND PSILOCINJournal of Neuropsychiatry and Clinical Neurosciences, 4
-
Donata Paresce, R. Ghosh, F. Maxfield (1996)
Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger ReceptorNeuron, 17
-
Richard Johnson, J. Glass, J. Mcarthur, B. Chesebro (1996)
Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndromeAnnals of Neurology, 39
-
H. Akiyama, K. Ikeda, M. Katoh, E. Mcgeer, P. Mcgeer (1994)
Expression of MRP14, 27E10, interferon-α and leukocyte common antigen by reactive microglia in postmortem human brain tissueJournal of Neuroimmunology, 50
-
J. Breitner (1996)
The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease.Annual review of medicine, 47
-
D. Gabuzda, D. Ho, S. Monte, M. Hirsch, T. Rota, R. Sobel (1986)
Immunohistochemical identification of HTLV‐III antigen in brains of patients with AIDSAnnals of Neurology, 20
-
G. Lees (1993)
The possible contribution of microglia and macrophages to delayed neuronal death after ischemiaJournal of the Neurological Sciences, 114
-
D. Pietraforte, E. Tritarelli, U. Testa, M. Minetti (1994)
gp120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte‐derived macrophagesJournal of Leukocyte Biology, 55
-
H. Gelbard, K. Dzenko, D. Diloreto, C. Cerro, M. Cerro, Leon Epstein (1993)
Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis.Developmental neuroscience, 15 6
-
Y. Zou, A. Kottmann, M. Kuroda, I. Taniuchi, D. Littman (1998)
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar developmentNature, 393
-
A. Klegeris, D. Walker, P. Mcgeer (1994)
Activation of Macrophages by Alzheimer β Amyloid PeptideBiochemical and Biophysical Research Communications, 199
-
S. Green, W. Phillips (1994)
Activation of the macrophage respiratory burst by phorbol myristate acetate: evidence for both tyrosine-kinase-dependent and -independent pathways.Biochimica et biophysica acta, 1222 2
-
D. Adamson, B. Wildemann, M. Sasaki, J. Glass, J. McArthur, Vesselin Christov, T. Dawson, V. Dawson (1996)
Immunologic NO Synthase: Elevation in Severe AIDS Dementia and Induction by HIV-1 gp41Science, 274
-
K. Williams, A. Bar-Or, E. Ulvestad, A. Olivier, J. Antel, V. Yong (1992)
Biology of Adult Human Microglia in Culture: Comparisons with Peripheral Blood Monocytes and AstrocytesJournal of Neuropathology and Experimental Neurology, 51
-
W. Qiu, Z. Ye, D. Kholodenko, P. Seubert, D. Selkoe (1997)
Degradation of Amyloid β-Protein by a Metalloprotease Secreted by Microglia and Other Neural and Non-neural Cells*The Journal of Biological Chemistry, 272
-
Leon Epstein, Leon Epstein, C. Kuiken, Benjamin Blumberg, Susan Hartman, L. Sharer, Marjon Clement, J. Goudsmit (1991)
HIV-1 V3 domain variation in brain and spleen of children with AIDS: tissue-specific evolution within host-determined quasispecies.Virology, 180 2
-
D. Theele, W. Streit (1993)
A chronicle of microglial ontogenyGlia, 7
-
L. Davis, B. Hjelle, V. Miller, D. Palmer, A. Llewellyn, T. Merlin, S. Young, R. Mills, W. Wachsman, C. Wiley (1992)
Early viral brain invasion in iatrogenic human immunodeficiency virus infectionNeurology, 42
-
H. Kettenmann, D. Hoppe, K. Gottmann, R. Banati, G. Kreutzberg (1990)
Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophagesJournal of Neuroscience Research, 26
-
Julie Strizki, A. Albright, Hai Sheng, M. O'Connor, Luc Perrin, F. González-Scarano (1996)
Infection of primary human microglia and monocyte-derived macrophages with human immunodeficiency virus type 1 isolates: evidence of differential tropismJournal of Virology, 70
-
N. Ruddle, C. Bergman, Katherine McGrath, E. Lingenheld, Margaret Grunnet, Steven Padula, Robert Clark (1990)
An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitisThe Journal of Experimental Medicine, 172
-
L. Lue, J. Rogers (1992)
Full complement activation fails in diffuse plaques of the Alzheimer's disease cerebellumDementia and Geriatric Cognitive Disorders, 3
-
D. Ho, A. Neumann, A. Perelson, Wen Chen, J. Leonard, M. Markowitz (1995)
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionNature, 373
-
H. Akiyama, P. Mcgeer (1990)
Brain microglia constitutively express β-2 integrinsJournal of Neuroimmunology, 30
-
B. Trapp, J. Peterson, R. Ransohoff, R. Rudick, S. Mørk, L. Bø (1998)
Axonal transection in the lesions of multiple sclerosis.The New England journal of medicine, 338 5
- Publisher
- Annual Reviews
- Copyright
- Copyright © 1999 by Annual Reviews. All rights reserved
- Subject
- Review Articles
- ISSN
- 0147-006X
- eISSN
- 1545-4126
- DOI
- 10.1146/annurev.neuro.22.1.219
- pmid
- 10202538
- Publisher site
- See Article on Publisher Site
Abstract
▪ Abstract Microglia are the principal immune cells in the central nervous system (CNS) and have a critical role in host defense against invading microorganisms and neoplastic cells. However, as with immune cells in other organs, microglia may play a dual role, amplifying the effects of inflammation and mediating cellular degeneration as well as protecting the CNS. In entities like human immunodeficiency virus (HIV) infection of the nervous system, microglia are also critical to viral persistence. In this review we discuss the role of microglia in three diseases in which their activity is at least partially deleterious: HIV, multiple sclerosis, and Alzheimer's disease.
Journal
Annual Review of Neuroscience – Annual Reviews
Published: Mar 1, 1999