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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived from that of the human c-myc gene product. Five of these antibodies precipitate p62c-myc from human cells, and three of these five also recognize the mouse c-myc gene product. None of the antibodies sees the chicken p110gag-myc protein. All six antibodies recognize immunoblotted p62c-myc. These reagents also provide the basis for an immunoblotting assay by which to quantitate p62c-myc in cells. Mol Cell Biol. 1985 December; 5(12): 3610-3616 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Molecular and Cellular Biology American Society For Microbiology

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Molecular and Cellular Biology , Volume 5 (12): 3610 – Dec 1, 1985

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Molecular and Cellular Biology , Volume 5 (12): 3610 – Dec 1, 1985

Abstract

Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived from that of the human c-myc gene product. Five of these antibodies precipitate p62c-myc from human cells, and three of these five also recognize the mouse c-myc gene product. None of the antibodies sees the chicken p110gag-myc protein. All six antibodies recognize immunoblotted p62c-myc. These reagents also provide the basis for an immunoblotting assay by which to quantitate p62c-myc in cells. Mol Cell Biol. 1985 December; 5(12): 3610-3616

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Publisher
American Society For Microbiology
Copyright
Copyright © 1985 by the American Society For Microbiology.
ISSN
0270-7306
eISSN
0270-7306
Publisher site
See Article on Publisher Site

Abstract

Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived from that of the human c-myc gene product. Five of these antibodies precipitate p62c-myc from human cells, and three of these five also recognize the mouse c-myc gene product. None of the antibodies sees the chicken p110gag-myc protein. All six antibodies recognize immunoblotted p62c-myc. These reagents also provide the basis for an immunoblotting assay by which to quantitate p62c-myc in cells. Mol Cell Biol. 1985 December; 5(12): 3610-3616

Journal

Molecular and Cellular BiologyAmerican Society For Microbiology

Published: Dec 1, 1985

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