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P. Keen, T. White (1970)
A LIGHT‐SCATTERING TECHNIQUE FOR THE STUDY OF THE PERMEABILITY OF RAT BRAIN SYNAPTOSOMES IN VITROJournal of Neurochemistry, 17
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Abstract— 1 The passive permeability of synaptosomes to ions was measured by a light‐scattering technique. Synaptosomes were freely permeable to acetate, HCO3_, SCN−and NH4+ and were impermeable to choline and SO42‐. 2 Gramicidin D selectively increased the permeability of synaptosomes to Na+ and K+ ions. 3 The relative permeabilities of Na+, K+ and Cl−, measured in the presence of a number of more permeant counter‐ions, was in the ratio 1:19:12. These values are discussed in terms of the source of the resting potential.
Journal of Neurochemistry – Wiley
Published: Jun 1, 1971
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