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Causes of mutation and Mu excision

Causes of mutation and Mu excision SCIENTIFIC CORRESPONDENCE population-level processes, which Cairns Causes of mutation and Mu excision 2 et al. did not adequately consider. These SIR-The results reported by Mittler and depended on variation plus natural selec­ include: (1) changes in the per capita Lenski' are completely different from tion. The second of these has received a rate of excision mutation with time, as ours'. They find that the ara-lac fusion huge amount of attention since the days of cells sit starving in the absence of lactose (which allows the Shapiro strain of Darwin and Wallace, but the first has or arabinose; (2) slight growth by Escherichia coli to utilize lactose when hardly been investigated at all. I can think MCS2 on lactose and arabinose, or trace arabinose is present) occurs at an ever­ of scarcely a dozen experiments that bear contaminants therein; (3) cross-feeding by increasing frequency in populations of upon the circumstances of what one might MCS2 due to metabolites released from starving bacteria in liquid medium, reach­ call normal spontaneous mutation. And if Lac(Arar excision mutants into the ing a level of more than 10- even in the one is interested in cancer (as I am), then medium; and (4) differences http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Springer Journals

Causes of mutation and Mu excision

MITTLER, JOHN E.; LENSKI, RICHARDE.
Nature , Volume 345 (6272) – May 17, 1990
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Causes of mutation and Mu excision

Abstract

SCIENTIFIC CORRESPONDENCE population-level processes, which Cairns Causes of mutation and Mu excision 2 et al. did not adequately consider. These SIR-The results reported by Mittler and depended on variation plus natural selec­ include: (1) changes in the per capita Lenski' are completely different from tion. The second of these has received a rate of excision mutation with time, as ours'. They find that the ara-lac fusion huge amount of attention since the days of cells sit...
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References (3)

Publisher
Springer Journals
Copyright
Copyright © 1990 by Nature Publishing Group
Subject
Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
ISSN
0028-0836
eISSN
1476-4687
DOI
10.1038/345213b0
Publisher site
See Article on Publisher Site

Abstract

SCIENTIFIC CORRESPONDENCE population-level processes, which Cairns Causes of mutation and Mu excision 2 et al. did not adequately consider. These SIR-The results reported by Mittler and depended on variation plus natural selec­ include: (1) changes in the per capita Lenski' are completely different from tion. The second of these has received a rate of excision mutation with time, as ours'. They find that the ara-lac fusion huge amount of attention since the days of cells sit starving in the absence of lactose (which allows the Shapiro strain of Darwin and Wallace, but the first has or arabinose; (2) slight growth by Escherichia coli to utilize lactose when hardly been investigated at all. I can think MCS2 on lactose and arabinose, or trace arabinose is present) occurs at an ever­ of scarcely a dozen experiments that bear contaminants therein; (3) cross-feeding by increasing frequency in populations of upon the circumstances of what one might MCS2 due to metabolites released from starving bacteria in liquid medium, reach­ call normal spontaneous mutation. And if Lac(Arar excision mutants into the ing a level of more than 10- even in the one is interested in cancer (as I am), then medium; and (4) differences

Journal

Nature – Springer Journals

Published: May 17, 1990

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