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ORIGINAL ARTICLES Prognostic Impact of Anatomic Resection for Hepatocellular Carcinoma Kiyoshi Hasegawa, MD, PhD,* Norihiro Kokudo, MD, PhD,* Hiroshi Imamura, MD, PhD,* Yutaka Matsuyama, PhD,† Taku Aoki, MD, PhD,* Masami Minagawa, MD, PhD,* Keiji Sano, MD, PhD,* Yasuhiko Sugawara, MD, PhD,* Tadatoshi Takayama, MD, PhD,‡ and Masatoshi Makuuchi, MD, PhD* the hazard ratios were 0.57 (95% confidence interval, 0.32– 0.99, Objectives: To evaluate the prognostic impact of anatomic versus P 0.04), and 0.65 (0.43– 0.96, P 0.03). nonanatomic resection on the patients’ survival after resection of a Conclusion: Anatomic resection for a single HCC yields more single hepatocellular carcinoma (HCC). favorable results rather than nonanatomic resection. Summary of Background Data: Anatomic resection is a reason- able treatment option for HCC; however, its clinical significance (Ann Surg 2005;242: 252–259) remains to be confirmed. Methods: Curative hepatic resection was performed for a single HCC in 210 patients; the patients were classified into the anatomic resection (n 156) and nonanatomic resection (n 54) groups. In epatocellular carcinoma (HCC) is one of the most com- 84 patients assigned to the anatomic resection group, segmentec- tomy or subsegmentectomy was performed. We evaluated the out- Hmon cancers worldwide. Hepatic resection is
Annals of Surgery – Wolters Kluwer Health
Published: Aug 1, 2005
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