Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/taylor-francis/pexophagy-the-selective-autophagy-of-peroxisomes-WUMdfarLbX
References (49)
-
Li Wang, E. Seeley, W. Wickner, A. Merz (2002)
Vacuole Fusion at a Ring of Vertex Docking Sites Leaves Membrane Fragments within the OrganelleCell, 108
-
Iryna Monastyrska, M. Heide, Arjen Krikken, J. Kiel, I. Klei, M. Veenhuis (2005)
Atg8 is Essential for Macropexophagy in Hansenula polymorphaTraffic, 6
-
J. Kiel, Janet Komduur, I. Klei, M. Veenhuis (2003)
Macropexophagy in Hansenula polymorpha: facts and viewsFEBS Letters, 549
-
D. Klionsky, J. Cregg, W. Dunn, S. Emr, Y. Sakai, I. Sandoval, A. Sibirny, S. Subramani, M. Thumm, M. Veenhuis, Y. Ohsumi (2003)
A unified nomenclature for yeast autophagy-related genes.Developmental cell, 5 4
-
A. Bellu, F. Salomons, J. Kiel, M. Veenhuis, I. Klei (2002)
Removal of Pex3p Is an Important Initial Stage in Selective Peroxisome Degradation in Hansenula polymorpha *The Journal of Biological Chemistry, 277
-
V. Titorenko, R. Rachubinski (2004)
The peroxisomeThe Journal of Cell Biology, 164
-
M. Veenhuis, J. Dijken, S.A.F. Pilon, Willem Harder (1978)
Development of crystalline peroxisomes in methanol-grown cells of the yeast Hansenula polymorpha and its relation to environmental conditionsArchives of Microbiology, 117
-
T. Shintani, Wei‐Pang Huang, P. Strømhaug, D. Klionsky (2002)
Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway.Developmental cell, 3 6
-
T. Nazarko, J. Nicaud, A. Sibirny (2005)
Observation of the Yarrowia lipolytica peroxisome—vacuole dynamics by fluorescence microscopy with a single filter setCell Biology International, 29
-
M. Kato, W. Wickner (2001)
Ergosterol is required for the Sec18/ATP‐dependent priming step of homotypic vacuole fusionThe EMBO Journal, 20
-
A. Bellu, I. Klei, K. Rechinger, M. Yavuz, Marten Veenhuis, J. Kiel (1999)
Characterization of the Hansenula polymorpha CPY gene encoding carboxypeptidase YYeast, 15
-
K. Suzuki, T. Kirisako, Y. Kamada, N. Mizushima, Takeshi Noda, Y. Ohsumi (2001)
The pre‐autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formationThe EMBO Journal, 20
-
Y. Ohsumi (2001)
Ubiquitin and proteasomes: Molecular dissection of autophagy: two ubiquitin-like systemsNature Reviews Molecular Cell Biology, 2
-
Jean-Claude Farré, S. Subramani (2004)
Peroxisome turnover by micropexophagy: an autophagy-related process.Trends in cell biology, 14 9
-
Xiaozhou Pan, D. Goldfarb (1998)
YEB3/VAC8 encodes a myristylated armadillo protein of the Saccharomyces cerevisiae vacuolar membrane that functions in vacuole fusion and inheritance.Journal of cell science, 111 ( Pt 15)
-
Adriana Leão, J. Kiel (2003)
Peroxisome homeostasis in Hansenula polymorpha.FEMS yeast research, 4 2
-
Y. Ano, Takeshi Hattori, Masahide Oku, H. Mukaiyama, M. Baba, Y. Ohsumi, N. Kato, Y. Sakai (2004)
A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate.Molecular biology of the cell, 16 2
-
John Kim, Y. Kamada, P. Strømhaug, J. Guan, A. Hefner-Gravink, M. Baba, S. Scott, Y. Ohsumi, W. Dunn, D. Klionsky (2001)
Cvt9/Gsa9 Functions in Sequestering Selective Cytosolic Cargo Destined for the VacuoleThe Journal of Cell Biology, 153
-
Cong-Zhao Zhou, Inès Sierra-Gallay, S. Quevillon-Cheruel, B. Collinet, P. Minard, K. Blondeau, G. Henckes, R. Aufrère, N. Leulliot, M. Graille, Isabelle Sorel, P. Savarin, Françoise Torre, A. Poupon, J. Janin, H. Tilbeurgh (2003)
Crystal Structure of the Yeast Phox Homology (PX) Domain Protein Grd19p Complexed to Phosphatidylinositol-3-phosphate*Journal of Biological Chemistry, 278
-
M. Veenhuis, M. Niet, W. Middelhoven (2004)
Biogenesis and metabolic significance of microbodies in urate-utilizing yeastsAntonie van Leeuwenhoek, 51
-
Katja Gunkel, I. Klei, G. Barth, M. Veenhuis (1999)
Selective peroxisome degradation in Yarrowia lipolytica after a shift of cells from acetate/oleate/ethylamine into glucose/ammonium sulfate‐containing mediaFEBS Letters, 451
-
Partha Hazra, I. Suriapranata, W. Snyder, S. Subramani (2002)
Peroxisome Remnants in pex3Δ Cells and the Requirement of Pex3p for Interactions Between the Peroxisomal Docking and Translocation SubcomplexesTraffic, 3
-
Adriana Leão-Helder, Arjen Krikken, G. Gellissen, I. Klei, M. Veenhuis, J. Kiel (2004)
Atg21p is essential for macropexophagy and microautophagy in the yeast Hansenula polymorphaFEBS Letters, 577
-
C Raymond, Christopher Roberts, Karen Moore, Isabelle Howald, T. Stevens (1992)
Biogenesis of the vacuole in Saccharomyces cerevisiae.International review of cytology, 139
-
Masahide Oku, D. Warnecke, Takeshi Noda, F. Müller, E. Heinz, H. Mukaiyama, N. Kato, Y. Sakai (2003)
Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domainThe EMBO Journal, 22
-
M. Veenhuis, M. Komori, F. Salomons, R. Hilbrands, H. Hut, R. Baerends, J. Kiel, I. Klei (1996)
Peroxisomal remnants in peroxisome‐deficient mutants of the yeast Hansenula polymorhaFEBS Letters, 383
-
O. Stasyk, T. Nazarko, O. Stasyk, Olena Krasovska, D. Warnecke, J. Nicaud, J. Cregg, A. Sibirny (2003)
Sterol glucosyltransferases have different functional roles inPichia pastoris and Yarrowia lipolyticaCell Biology International, 27
-
D. Klionsky (2003)
Cytoplasm to Vacuole Targeting -
Daniel Nice, Trey Sato, P. Strømhaug, S. Emr, D. Klionsky (2002)
Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy*The Journal of Biological Chemistry, 277
-
T. Nazarko, Ju Huang, J. Nicaud, D. Klionsky, A. Sibirny (2005)
Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae.Autophagy, 1 1
-
Y. Sakai, A. Koller, Linda Rangell, G. Keller, S. Subramani (1998)
Peroxisome Degradation by Microautophagy in Pichia pastoris: Identification of Specific Steps and Morphological IntermediatesThe Journal of Cell Biology, 141
-
M. Veenhuis, W. Harder, J. Dijken, F. Mayer (1981)
Substructure of crystalline peroxisomes in methanol-grown Hansenula polymorpha: evidence for an in vivo crystal of alcohol oxidaseMolecular and Cellular Biology, 1
-
Adriana Leão-Helder, Arjen Krikken, I. Klei, J. Kiel, M. Veenhuis (2003)
Transcriptional Down-regulation of Peroxisome Numbers Affects Selective Peroxisome Degradation in Hansenula polymorpha*Journal of Biological Chemistry, 278
-
O. Stasyk, I. Klei, A. Bellu, S. Shen, J. Kiel, J. Cregg, M. Veenhuis (1999)
A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagyCurrent Genetics, 36
-
Yong-Xu Wang, Natalie Catlett, L. Weisman (1998)
Vac8p, a Vacuolar Protein with Armadillo Repeats, Functions in both Vacuole Inheritance and Protein Targeting from the Cytoplasm to VacuoleThe Journal of Cell Biology, 140
-
P. Strømhaug, A. Bevan, W. Dunn (2001)
GSA11 Encodes a Unique 208-kDa Protein Required for Pexophagy and Autophagy in Pichia pastoris *The Journal of Biological Chemistry, 276
-
D. Klionsky (1997)
Protein Transport from the Cytoplasm into the VacuoleThe Journal of Membrane Biology, 157
-
H. Mukaiyama, M. Baba, M. Osumi, Satoshi Aoyagi, N. Kato, Y. Ohsumi, Y. Sakai (2003)
Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure.Molecular biology of the cell, 15 1
-
Janet Komduur, M. Veenhuis, J. Kiel (2003)
The Hansenula polymorpha PDD7 gene is essential for macropexophagy and microautophagy.FEMS yeast research, 3 1
-
R. Dijk, K. Faber, A. Hammond, B. Glick, M. Veenhuis, J. Kiel (2001)
Tagging Hansenula polymorpha genes by random integration of linear DNA fragments (RALF)Molecular Genetics and Genomics, 266
-
Weiping Yuan, P. Strømhaug, W. Dunn (1999)
Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein.Molecular biology of the cell, 10 5
-
A. Bellu, M. Komori, I. Klei, J. Kiel, M. Veenhuis (2001)
Peroxisome Biogenesis and Selective Degradation Converge at Pex14p*The Journal of Biological Chemistry, 276
-
B. Dujon, D. Sherman, Gilles Fischer, P. Durrens, S. Casaregola, I. Lafontaine, J. Montigny, C. Marck, C. Neuvéglise, E. Talla, N. Goffard, L. Frangeul, M. Aigle, Véronique Anthouard, A. Babour, V. Barbe, S. Barnay, Sylvie Blanchin, J. Beckerich, Emmanuelle Beyne, C. Bleykasten, A. Boisramé, J. Boyer, L. Cattolico, Fabrice Confanioleri, A. Daruvar, L. Despons, E. Fabre, C. Fairhead, H. Ferry‐Dumazet, A. Groppi, Florence Hantraye, C. Hennequin, Nicolas Jauniaux, P. Joyet, Rym Kachouri, A. Kerrest, R. Koszul, M. Lemaire, I. Lesur, Laurence Ma, H. Muller, J. Nicaud, M. Nikolski, S. Oztas, O. Ozier‐Kalogeropoulos, Stefan Pellenz, S. Potier, G. Richard, Marie-Laure Straub, Audrey Suleau, D. Swennen, F. Tekaia, M. Wésolowski-Louvel, E. Westhof, B. Wirth, Maria Zeniou‐Meyer, I. Živanović, M. Bolotin‐Fukuhara, A. Thierry, C. Bouchier, B. Caudron, C. Scarpelli, C. Gaillardin, J. Weissenbach, P. Wincker, J. Souciet (2004)
Genome evolution in yeastsNature, 430
-
A. Bellu, A. Kram, J. Kiel, M. Veenhuis, I. Klei (2001)
Glucose-induced and nitrogen-starvation-induced peroxisome degradation are distinct processes in Hansenula polymorpha that involve both common and unique genes.FEMS yeast research, 1 1
-
Yoshinobu Ichimura, T. Kirisako, T. Takao, Y. Satomi, Y. Shimonishi, Naotada Ishihara, N. Mizushima, I. Tanida, E. Kominami, M. Ohsumi, Takeshi Noda, Y. Ohsumi (2000)
A ubiquitin-like system mediates protein lipidationNature, 408
-
H. Mukaiyama, Masahide Oku, M. Baba, Takeshi Samizo, A. Hammond, B. Glick, N. Kato, Y. Sakai (2002)
Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagyGenes to Cells, 7
-
J. Guan, P. Strømhaug, P. Strømhaug, Michael George, Pouran Habibzadegah-Tari, Andrew Bevan, W. Dunn, D. Klionsky (2001)
Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris.Molecular biology of the cell, 12 12
-
Weiping Yuan, Daniel Tuttle, Yu-Jiang Shi, Gareth Ralph, William Dunn (1997)
Glucose-induced microautophagy in Pichia pastoris requires the alpha-subunit of phosphofructokinase.Journal of cell science, 110 ( Pt 16)
-
J. Kiel, K. Rechinger, I. Klei, F. Salomons, V. Titorenko, M. Veenhuis (1999)
The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34pYeast, 15
- Publisher
- Taylor & Francis
- Copyright
- Copyright © 2005 Landes Bioscience
- ISSN
- 1554-8635
- eISSN
- 1554-8627
- DOI
- 10.4161/auto.1.2.1737
- Publisher site
- See Article on Publisher Site
Abstract
Pichia pastoris and Hanseula polymorpha are methylotrophic yeasts capable of utilizing methanol, as a sole source of carbon and energy. Growth of these yeast species on methanol requires the synthesis of cytosolic and peroxisomal enzymes combined with the proliferation of peroxisomes. Peroxisomes are also abundantly present in the alkane-utilizing yeast Yarrowia lipolytica upon growth of cells on oleic acid. This feature has made these yeast species attractive model systems to dissect the molecular mechanisms controlling peroxisome biogenesis. We have found that upon glucose- or ethanol-induced catabolite inactivation of metabolically superfluous peroxisomes are rapidly and selectively degraded within the vacuole by a process called pexophagy, the selective removal of peroxisomes by autophagy-like processes. Utilizing several genetic screens, we have identified a number of genes that are essential for pexophagy. In this review, we will summarize our current knowledge of the molecular events of pexophagy.
Journal
Autophagy – Taylor & Francis
Published: Jul 5, 2005