E. White, R. DiPaola (2009)
The Double-Edged Sword of Autophagy Modulation in CancerClinical Cancer Research, 15
Lin Li, R. Zhou, Tuoxiu Zhong, L. Moon, Eun Kim, H. Qiao, S. Pickup, M. Hendrix, D. Leeper, B. Chance, J. Glickson (2007)
Predicting melanoma metastatic potential by optical and magnetic resonance imaging.Advances in experimental medicine and biology, 599
G. Kroemer, L. Galluzzi, P. Vandenabeele, J. Abrams, Es Alnemri, Eh Baehrecke, M. Blagosklonny, WS El-Deiry, P. Golstein, D. Green, M. Hengartner, RA Knight, S. Kumar, SA Lipton, W. Malorni, G. Núñez, ME Peter, J. Tschopp, J. Yuan, M. Piacentini, B. Zhivotovsky, G. Melino (2005)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009Cell Death and Differentiation, 16
C. Bellodi, M. Lidonnici, A. Hamilton, G. Helgason, A. Soliera, M. Ronchetti, S. Galavotti, K. Young, Tommaso Selmi, R. Yacobi, R. Etten, N. Donato, A. Hunter, D. Dinsdale, E. Tirrò, P. Vigneri, P. Nicotera, M. Dyer, T. Holyoake, P. Salomoni, K. Funai, Haowei Song, L. Yin, I. Lodhi, Xiaochao Wei, J. Yoshino, T. Coleman, C. Semenkovich, Aldo Roccaro, A. Sacco, P. Maiso, A. Azab, Y. Tai, M. Reagan, F. Azab, L. Flores, F. Campigotto, E. Weller, K. Anderson, D. Scadden, I. Ghobrial, S. Ramachandrappa, Anne Raimondo, A. Calí, J. Keogh, E. Henning, Sadia Saeed, A. Thompson, Sumedha Garg, Elena Bochukova, S. Brage, Victoria Trowse, E. Wheeler, Adrienne Sullivan, M. Dattani, Peter Clayton, V. Datta, J. Bruning, N. Wareham, S. O’Rahilly, D. Peet, I. Barroso, M. Whitelaw, S. Farooqi (2009)
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.The Journal of clinical investigation, 119 5
X. Wan, Xin-Juan Fan, Ming-Yuan Chen, J. Xiang, Pei-yu Huang, Ling Guo, Xiang-yuan Wu, Jie Xu, Zi-Jie Long, Yan Zhao, Wei-hua Zhou, H. Mai, Quentin Liu, M. Hong (2010)
Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinomaAutophagy, 6
R. Mathew, S. Kongara, Brian Beaudoin, C. Karp, K. Bray, K. Degenhardt, Guanghua Chen, Shengkan Jin, E. White (2007)
Autophagy suppresses tumor progression by limiting chromosomal instability.Genes & development, 21 11
T. Kanzawa, I. Germano, T. Komata, Hideaki Ito, Hideaki Ito, Y. Kondo, Y. Kondo, Seiji Kondo, Seiji Kondo (2004)
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cellsCell Death and Differentiation, 11
Jianrong Wang, Mary Whiteman, Huiqin Lian, Guangxin Wang, Ashutosh Singh, Dongyang Huang, Ted Denmark (2009)
A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1*The Journal of Biological Chemistry, 284
He Xu, R. Zhou, S. Nioka, B. Chance, J. Glickson, Lin Li (2009)
Histological basis of MR/optical imaging of human melanoma mouse xenografts spanning a range of metastatic potentials.Advances in experimental medicine and biology, 645
(2011)
American Association for Cancer clincancerres.aacrjournals.org Downloaded from
Lin Li, R. Zhou, He Xu, L. Moon, Tuoxiu Zhong, Eun Kim, H. Qiao, R. Reddy, D. Leeper, B. Chance, J. Glickson (2009)
Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potentialProceedings of the National Academy of Sciences, 106
R. Amaravadi, Duonan Yu, J. Lum, Thi Bui, M. Christophorou, G. Evan, A. Thomas-Tikhonenko, C. Thompson (2007)
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma.The Journal of clinical investigation, 117 2
R. Amaravadi, C. Thompson (2007)
The Roles of Therapy-Induced Autophagy and Necrosis in Cancer TreatmentClinical Cancer Research, 13
N. Mizushima, B. Levine, A. Cuervo, D. Klionsky (2008)
Autophagy fights disease through cellular self-digestionNature, 451
D. Welch, J. Bisi, B. Miller, D. Conaway, E. Seftor, K. Yohem, L. Gilmore, Richard Seftor, M. Nakajima, M. Hendrix (1991)
Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell lineInternational Journal of Cancer, 47
J. Carew, S. Nawrocki, C. Kahue, Hui Zhang, Chunying Yang, Linda Chung, J. Houghton, Peng Huang, F. Giles, J. Cleveland (2007)
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance.Blood, 110 1
Ana Silva, J. Yunes, B. Cardoso, L. Martins, P. Jotta, M. Abecasis, A. Nowill, N. Leslie, A. Cardoso, J. Barata (2008)
PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability.The Journal of clinical investigation, 118 11
M. Hendrix, M. Hendrix, E. Seftor, E. Seftor, Richard Seftor, Richard Seftor, Isaiah Fidler, Isaiah Fidler (1987)
A simple quantitative assay for studying the invasive potential of high and low human metastatic variants.Cancer letters, 38 1-2
(2008)
J Clin Invest
M. Maiuri, E. Tasdemir, E. Tasdemir, A. Criollo, A. Criollo, E. Morselli, E. Morselli, J. Vicencio, J. Vicencio, R. Carnuccio, G. Kroemer, G. Kroemer (2009)
Control of autophagy by oncogenes and tumor suppressor genesCell Death and Differentiation, 16
A. Ganesan, Hsiang Ho, Brian Bodemann, S. Petersen, Jayavani Aruri, Shiney Koshy, Zachary Richardson, L. Le, T. Krasieva, M. Roth, P. Farmer, M. White (2008)
Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human CellsPLoS Genetics, 4
R. Amaravadi, L. Schuchter, D. McDermott, A. Kramer, L. Giles, Kristi Gramlich, Mary Carberry, A. Troxel, R. Letrero, K. Nathanson, M. Atkins, P. O'dwyer, K. Flaherty (2009)
Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain MetastasesClinical Cancer Research, 15
R. Mathew, C. Karp, Brian Beaudoin, N. Vuong, Guanghua Chen, Hsin Chen, K. Bray, Anupama Reddy, G. Bhanot, C. Gélinas, R. DiPaola, V. Karantza-Wadsworth, E. White (2011)
Autophagy Suppresses Tumorigenesis through Elimination of p62Cell, 145
J. Lum, D. Bauer, M. Kong, M. Harris, Chi Li, T. Lindsten, C. Thompson (2005)
Growth Factor Regulation of Autophagy and Cell Survival in the Absence of ApoptosisCell, 120
(2011)
aacrjournals.org Clin Cancer Res
T. Rzymski, M. Milani, Luke Pike, F. Buffa, H. Mellor, L. Winchester, Isabel Pires, E. Hammond, I. Ragoussis, A. Harris (2010)
Regulation of autophagy by ATF4 in response to severe hypoxiaOncogene, 29
R. Amaravadi, K. Flaherty (2007)
Targeted therapy for metastatic melanoma.Clinical advances in hematology & oncology : H&O, 5 5
M. Luca, B. Hunt, C. Bucana, J. Johnson, Isaiah Fidler, M. Bar‐eli (1993)
Direct correlation between MUC18 expression and metastatic potential of human melanoma cells.Melanoma research, 3 1
K. Smalley, R. Contractor, Thiennga Nguyen, M. Xiao, R. Edwards, Viswanathan Muthusamy, A. King, K. Flaherty, M. Bosenberg, M. Herlyn, K. Nathanson (2008)
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.Cancer research, 68 14
L. Fecher, R. Amaravadi, K. Flaherty (2008)
The MAPK pathway in melanomaCurrent Opinion in Oncology, 20
(2011)
Author Manuscript Published OnlineFirst on February
X. Qu, Jie Yu, G. Bhagat, Norihiko Furuya, H. Hibshoosh, A. Troxel, J. Rosen, E. Eskelinen, N. Mizushima, Y. Ohsumi, G. Cattoretti, B. Levine (2003)
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene.The Journal of clinical investigation, 112 12
Zhen Lu, R. Luo, Yiling Lu, Xuhui Zhang, Qinghua Yu, Shilpi Khare, S. Kondo, Y. Kondo, Yin-hua Yu, G. Mills, W. Liao, R. Bast (2008)
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.The Journal of clinical investigation, 118 12
K. Smalley, N. Haass, P. Brafford, Mercedes Lioni, K. Flaherty, M. Herlyn (2006)
Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastasesMolecular Cancer Therapeutics, 5
W. Ding, Hong-Min Ni, Wentao Gao, Xiaoyun Chen, J. Kang, D. Stolz, Jinsong Liu, Xiao-Ming Yin (2009)
Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagyMolecular Cancer Therapeutics, 8
Russell Jones, C. Thompson (2009)
Tumor suppressors and cell metabolism: a recipe for cancer growth.Genes & development, 23 5
E. Korn, Ping-Yu Liu, Sandra Lee, J. Chapman, D. Niedzwiecki, V. Suman, J. Moon, V. Sondak, M. Atkins, E. Eisenhauer, W. Parulekar, S. Markovic, S. Saxman, J. Kirkwood (2008)
Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26 4
I. Tanida, T. Ueno, E. Kominami (2004)
LC3 conjugation system in mammalian autophagyThe International Journal of Biochemistry & Cell Biology, 36
G. Kroemer, W. El-Deiry, P. Golstein, M. Peter, D. Vaux, P. Vandenabeele, B. Zhivotovsky, M. Blagosklonny, W. Malorni, R. Knight, M. Piacentini, S. Nagata, G. Melino (2005)
Classification of cell death: recommendations of the Nomenclature Committee on Cell DeathCell Death and Differentiation, 12
Nityanand Maddodi, Wei Huang, T. Havighurst, KyungMann Kim, B. Longley, V. Setaluri (2010)
Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.The Journal of investigative dermatology, 130 6
K. Degenhardt, R. Mathew, Brian Beaudoin, K. Bray, Diana Anderson, Guanghua Chen, Chandreyee Mukherjee, Yufang Shi, C. Gélinas, Yongjun Fan, D. Nelson, Shengkan Jin, E. White (2006)
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.Cancer cell, 10 1
J. Villanueva, A. Vultur, John Lee, R. Somasundaram, M. Fukunaga-Kalabis, Angela Cipolla, B. Wubbenhorst, Xiaowei Xu, P. Gimotty, D. Kee, A. Santiago-Walker, R. Letrero, K. D’Andrea, A. Pushparajan, James Hayden, K. Brown, S. Laquerre, G. McArthur, J. Sosman, K. Nathanson, M. Herlyn (2010)
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.Cancer cell, 18 6
片山 真 (2009)
DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
E. Seftor, R. Seftor, M. Hendrix (1990)
Selection of invasive and metastatic subpopulations from a heterogeneous human melanoma cell line.BioTechniques, 9 3
K. Maclean, F. Dorsey, J. Cleveland, M. Kastan (2008)
Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.The Journal of clinical investigation, 118 1
Cancer Epidemiology, Biomarkers and Prevention – Unpaywall
Published: Feb 16, 2011
Access the full text.
Sign up today, get DeepDyve free for 14 days.