Ai-di Gu, Yunqi Wang, Lin Lin, Song Zhang, Y. Wan (2012)
Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functionsProceedings of the National Academy of Sciences, 109
J. Marie, D. Liggitt, A. Rudensky (2006)
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor.Immunity, 25 3
V. Todorovic, D. Rifkin (2012)
LTBPs, more than just an escort serviceJournal of Cellular Biochemistry, 113
J. Proctor, K. Zang, Denan Wang, Rong Wang, L. Reichardt (2005)
Vascular Development of the Brain Requires β8 Integrin Expression in the NeuroepitheliumThe Journal of Neuroscience, 25
J. Konkel, T. Maruyama, Andrea Carpenter, Y. Xiong, B. Zamarron, B. Hall, A. Kulkarni, Pin Zhang, R. Bosselut, Wanjun Chen (2011)
Control of CD8αα intestinal intraepithelial lymphocyte development by TGF-βNature immunology, 12
Soichi Tofukuji, M. Kuwahara, Junpei Suzuki, O. Ohara, T. Nakayama, M. Yamashita (2012)
Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-βThe Journal of Immunology, 188
Y. Tone, K. Furuuchi, Yoshitsugu Kojima, M. Tykocinski, M. Greene, M. Tone (2008)
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancerNature Immunology, 9
B. Dabovic, Yan Chen, Cristina Colarossi, L. Zambuto, H. Obata, Daniel Rifkin (2002)
Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation.The Journal of endocrinology, 175 1
R. Tinoco, Víctor Alcalde, Yating Yang, K. Sauer, E. Zúñiga (2009)
Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo.Immunity, 31 1
A. Tatler, A. John, L. Jolly, A. Habgood, J. Porte, C. Brightling, A. Knox, L. Pang, D. Sheppard, Xiaozhu Huang, G. Jenkins (2011)
Integrin αvβ5-Mediated TGF-β Activation by Airway Smooth Muscle Cells in AsthmaThe Journal of Immunology, 187
Min Lu, J. Munger, Melissa Steadele, C. Busald, M. Tellier, L. Schnapp (2002)
Integrin α8β1 mediates adhesion to LAP-TGFβ1Journal of Cell Science, 115
G. Nijbroek, Sumesh Sood, lain Mcintosh, A. Clair, Francomano, Evelyn Bull, L. Pereira, Francesco Ramirez, Reed Pyeritz, Harry Dietz (1995)
Fifteen novel FBN1 mutations causing Marfan syndrome detected by heteroduplex analysis of genomic amplicons.American journal of human genetics, 57 1
K. Sugimoto, M. Kudo, A. Sundaram, X. Ren, Katherine Huang, X. Bernstein, Yanli Wang, W. Raymond, D. Erle, M. Åbrink, G. Caughey, Xiaozhu Huang, D. Sheppard (2012)
The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.The Journal of clinical investigation, 122 2
F. Regateiro, D. Howie, K. Nolan, E. Agorogiannis, D. Greaves, S. Cobbold, H. Waldmann (2011)
Generation of anti‐inflammatory adenosine byleukocytes is regulated by TGF‐βEuropean Journal of Immunology, 41
Y. Asano, H. Ihn, K. Yamane, M. Jinnin, Y. Mimura, K. Tamaki (2005)
Increased Expression of Integrin αvβ3 Contributes to the Establishment of Autocrine TGF-β Signaling in Scleroderma Fibroblasts1The Journal of Immunology, 175
Yabing Mu, Shyam Gudey, M. Landström (2011)
Non-Smad signaling pathwaysCell and Tissue Research, 347
H. Strobl, W. Knapp (1999)
TGF-β1 regulation of dendritic cellsMicrobes and Infection, 1
Eva Acosta-Rodriguez, G. Napolitani, A. Lanzavecchia, F. Sallusto (2007)
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cellsNature Immunology, 8
S. Floess, Jennifer Freyer, C. Siewert, U. Baron, S. Olek, J. Polansky, Kerstin Schlawe, Hyun-Dong Chang, T. Bopp, E. Schmitt, S. Klein-Hessling, E. Serfling, A. Hamann, J. Huehn (2007)
Epigenetic Control of the foxp3 Locus in Regulatory T CellsPLoS Biology, 5
M. Veldhoen, C. Uyttenhove, J. Snick, H. Helmby, A. Westendorf, J. Buer, Bruno Martin, C. Wilhelm, B. Stockinger (2008)
Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subsetNature Immunology, 9
Todd Davidson, R. DiPaolo, J. Andersson, E. Shevach (2007)
Cutting Edge: IL-2 Is Essential for TGF-β-Mediated Induction of Foxp3+ T Regulatory CellsThe Journal of Immunology, 178
Helena Paı̈dassi, Mridu Acharya, Ailiang Zhang, S. Mukhopadhyay, Manjae Kwon, C. Chow, L. Stuart, J. Savill, A. Lacy-Hulbert (2011)
Preferential expression of integrin αvβ8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells.Gastroenterology, 141 5
Mridu Acharya, S. Mukhopadhyay, Helena Paı̈dassi, Tahseen Jamil, C. Chow, S. Kissler, L. Stuart, R. Hynes, A. Lacy-Hulbert (2010)
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.The Journal of clinical investigation, 120 12
(2010)
Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development
W. Ouyang, Soyoung Oh, Q. Ma, Michael Bivona, Jinfang Zhu, Ming Li (2013)
TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression.Immunity, 39 2
Jinfang Zhu, Todd Davidson, Gang Wei, Dragana Jankovic, Kairong Cui, Dustin Schones, Liying Guo, K. Zhao, E. Shevach, W. Paul (2009)
Down-regulation of Gfi-1 expression by TGF-β is important for differentiation of Th17 and CD103+ inducible regulatory T cellsThe Journal of Experimental Medicine, 206
L. Gorelik, R. Flavell (2000)
Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune DiseaseImmunity, 12
S. Jana, Parthav Jailwala, Dipica Haribhai, J. Waukau, S. Glišić, W. Grossman, Manoj Mishra, R. Wen, Demin Wang, C. Williams, Soumitra Ghosh (2009)
The role of NF‐κB and Smad3 in TGF‐β‐mediated Foxp3 expressionEuropean Journal of Immunology, 39
R. Jabeen, M. Kaplan (2012)
The symphony of the ninth: the development and function of Th9 cells.Current opinion in immunology, 24 3
G. Hansen, J. McIntire, V. Yeung, G. Berry, G. Thorbecke, Lizhen Chen, R. DeKruyff, D. Umetsu (2000)
CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation.The Journal of clinical investigation, 105 1
Anna Cebula, M. Seweryn, G. Rempała, S. Pabla, R. McIndoe, T. Denning, L. Bry, P. Kraj, P. Kisielow, L. Ignatowicz (2013)
Thymus-derived regulatory T cells control tolerance to commensal microbiotaNature, 497
A. Kulkarni, C. Huh, D. Becker, A. Geiser, Marion Lyght, K. Flanders, A. Roberts, M. Sporn, Jerrold Ward, S. Karlsson (1993)
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.Proceedings of the National Academy of Sciences of the United States of America, 90
M. Guilliams, K. Crozat, S. Henri, Samira Tamoutounour, P. Grenot, E. Devilard, B. Bovis, L. Alexopoulou, M. Dalod, B. Malissen (2010)
Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells.Blood, 115 10
G. Monteleone, A. Kumberová, N. Croft, C. McKenzie, H. Steer, T. Macdonald (2001)
Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease.The Journal of clinical investigation, 108 4
Kohel Miyazono, C. Heldin (1989)
Role for carbohydrate structures inTGF-β1 latencyNature, 338
Wanjun Chen, W. Jin, N. Hardegen, K. Lei, Li Li, N. Marinos, G. McGrady, S. Wahl (2003)
Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3The Journal of Experimental Medicine, 198
Shomyseh Sanjabi, Munir Mosaheb, R. Flavell (2009)
Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells.Immunity, 31 1
Xuexian Yang, R. Nurieva, G. Martinez, Hong Kang, Yeonseok Chung, B. Pappu, Bhavin Shah, S. Chang, K. Schluns, S. Watowich, Xin-Hua Feng, A. Jetten, C. Dong (2008)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs.Immunity, 29 1
Ling Lu, Julie Wang, Feng Zhang, Y. Chai, D. Brand, Xuehao Wang, D. Horwitz, W. Shi, S. Zheng (2010)
Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T CellsThe Journal of Immunology, 184
Zhiwei Yang, Z. Mu, B. Dabovic, V. Jurukovski, Dawen Yu, J. Sung, Xiaozhong Xiong, J. Munger (2007)
Absence of integrin-mediated TGFβ1 activation in vivo recapitulates the phenotype of TGFβ1-null miceThe Journal of Cell Biology, 176
J. Kehrl, L. Wakefield, A. Roberts, S. Jakowlew, M. Alvarez-Mon, R. Derynck, M. Sporn, A. Fauci (1986)
Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growthThe Journal of Experimental Medicine, 163
K. Rabinowitz, Yuanyuan Wang, E. Chen, Z. Hovhannisyan, David Chiang, M. Berin, S. Dahan, D. Chaussabel, Avi Ma’ayan, L. Mayer (2013)
Transforming growth factor β signaling controls activities of human intestinal CD8(+)T suppressor cells.Gastroenterology, 144 3
Yigong Shi, J. Massagué (2003)
Mechanisms of TGF-β Signaling from Cell Membrane to the NucleusCell, 113
J. Massagué (2012)
TGFβ signalling in contextNature Reviews Molecular Cell Biology, 13
X. Huang, J. Wu, D. Cass, D. Erle, D. Corry, S. Young, Robert Farese, D. Sheppard (2002)
Inactivation of the Integrin [36 Subunit Gene Reveals a Role of Epithelial Integrins in Regulating Inflammation in the Lungs and Skin
J. Marie, J. Letterio, M. Gavin, A. Rudensky (2005)
TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cellsThe Journal of Experimental Medicine, 201
R. Smeltz, June-Home Chen, E. Shevach (2005)
Transforming growth factor‐β1 enhances the interferon‐γ‐dependent, interleukin‐12‐independent pathway of T helper 1 cell differentiationImmunology, 114
M. Pesu, W. Watford, Lai Wei, Lili Xu, I. Fuss, W. Strober, J. Andersson, E. Shevach, M. Quezado, N. Bouladoux, A. Roebroek, Y. Belkaid, J. Creemers, J. O’Shea (2008)
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune toleranceNature, 455
Marilyn Giacomini, M. Travis, M. Kudo, D. Sheppard (2012)
Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin α(v)β(6)-dependent physical force.Experimental cell research, 318 6
J. Munger, J. Harpel, F. Giancotti, D. Rifkin (1998)
Interactions between Growth Factors and Integrins: Latent Forms of Transforming Growth Factor-β Are Ligands for the Integrin αvβ1Molecular Biology of the Cell, 9
E. Neptune, P. Frischmeyer, D. Arking, Loretha Myers, T. Bunton, B. Gayraud, F. Ramirez, L. Sakai, H. Dietz (2003)
Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndromeNature Genetics, 33
Dipica Haribhai, Jason Williams, S. Jia, Derek Nickerson, Erica Schmitt, B. Edwards, Jennifer Ziegelbauer, M. Yassai, Shun-Hwa Li, Lance Relland, Petra Wise, Andrew Chen, Yu-Qian Zheng, P. Simpson, J. Gorski, N. Salzman, M. Hessner, T. Chatila, C. Williams (2011)
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity.Immunity, 35 1
L. Gorelik, S. Constant, R. Flavell (2002)
Mechanism of Transforming Growth Factor β–induced Inhibition of T Helper Type 1 DifferentiationThe Journal of Experimental Medicine, 195
S. Josefowicz, Li-Fan Lu, A. Rudensky (2012)
Regulatory T cells: mechanisms of differentiation and function.Annual review of immunology, 30
J. Worthington, Joanna Klementowicz, M. Travis (2011)
TGFβ: a sleeping giant awoken by integrins.Trends in biochemical sciences, 36 1
K. Ichiyama, H. Yoshida, Y. Wakabayashi, T. Chinen, Kazuko Saeki, M. Nakaya, G. Takaesu, S. Hori, A. Yoshimura, Takashi Kobayashi (2008)
Foxp3 Inhibits RORγt-mediated IL-17A mRNA Transcription through Direct Interaction with RORγt*♦Journal of Biological Chemistry, 283
J. Annes, D. Rifkin, J. Munger (2002)
The integrin αVβ6 binds and activates latent TGFβ3FEBS Letters, 511
T. Borkowski, J. Letterio, A. Farr, M. Udey (1996)
A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans CellsThe Journal of Experimental Medicine, 184
T. Bauer, A. Zagórska, Jennifer Jurkin, N. Yasmin, René Köffel, S. Richter, Bernhard Gesslbauer, G. Lemke, H. Strobl (2012)
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasisThe Journal of Experimental Medicine, 209
Youjin Lee, A. Awasthi, N. Yosef, F. Quintana, S. Xiao, A. Peters, Chuan Wu, Markus Kleinewietfeld, Sharon Kunder, D. Hafler, R. Sobel, A. Regev, V. Kuchroo (2012)
Induction and molecular signature of pathogenic TH17 cellsNature immunology, 13
J. Worthington, Beata Czajkowska, A. Melton, M. Travis (2011)
Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8Gastroenterology, 141
J. Hill, J. Hall, Cheng-Ming Sun, Qi Cai, N. Ghyselinck, P. Chambon, Y. Belkaid, D. Mathis, C. Benoist (2008)
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.Immunity, 29 5
J. Jovanovic, S. Iqbal, S. Jensen, H. Mardon, P. Handford (2008)
Fibrillin-integrin interactions in health and disease.Biochemical Society transactions, 36 Pt 2
A. Nakao, M. Afrakhte, A. Morn, T. Nakayama, J. Christian, R. Heuchel, S. Itoh, M. Kawabata, N. Heldin, C. Heldin, P. Dijke (1997)
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signallingNature, 389
K. Ichiyama, T. Sekiya, N. Inoue, Taiga Tamiya, Ikko Kashiwagi, A. Kimura, R. Morita, Go Muto, T. Shichita, Reiko Takahashi, A. Yoshimura (2011)
Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.Immunity, 34 5
S. McKarns, R. Schwartz (2005)
Distinct Effects of TGF-β1 on CD4+ and CD8+ T Cell Survival, Division, and IL-2 Production: A Role for T Cell Intrinsic Smad3The Journal of Immunology, 174
Nu Zhang, M. Bevan (2012)
Transforming growth factor-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferationNature immunology, 13
N. Sawamukai, A. Satake, A. Schmidt, Ian Lamborn, P. Ojha, Yoshiya Tanaka, T. Kambayashi (2012)
Cell-autonomous role of TGFβ and IL-2 receptors in CD4+ and CD8+ inducible regulatory T-cell generation during GVHD.Blood, 119 23
Ming Li, Y. Wan, Shomyseh Sanjabi, A. Robertson, R. Flavell (2006)
Transforming growth factor-beta regulation of immune responses.Annual review of immunology, 24
A. Cerwenka, H. Kovar, O. Majdic, W. Holter (1996)
Fas- and activation-induced apoptosis are reduced in human T cells preactivated in the presence of TGF-beta 1.Journal of immunology, 156 2
Anupriya Khare, N. Krishnamoorthy, T. Oriss, M. Fei, P. Ray, A. Ray (2013)
Cutting Edge: Inhaled Antigen Upregulates Retinaldehyde Dehydrogenase in Lung CD103+ but Not Plasmacytoid Dendritic Cells To Induce Foxp3 De Novo in CD4+ T Cells and Promote Airway ToleranceThe Journal of Immunology, 191
R. Goswami, R. Jabeen, Ryoji Yagi, Duy Pham, Jinfang Zhu, S. Goenka, M. Kaplan (2012)
STAT6-Dependent Regulation of Th9 DevelopmentThe Journal of Immunology, 188
H. Kitamura, S. Cambier, Sangeeta Somanath, T. Barker, S. Minagawa, Jennifer Markovics, Amanda Goodsell, Jean Publicover, L. Reichardt, D. Jablons, P. Wolters, Arthur Hill, J. Marks, J. Lou, J. Pittet, J. Gauldie, J. Baron, S. Nishimura (2011)
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.The Journal of clinical investigation, 121 7
Hiromi Takaki, K. Ichiyama, K. Koga, T. Chinen, G. Takaesu, Y. Sugiyama, S. Kato, A. Yoshimura, Takashi Kobayashi (2008)
STAT6 Inhibits TGF-β1-mediated Foxp3 Induction through Direct Binding to the Foxp3 Promoter, Which Is Reverted by Retinoic Acid Receptor*Journal of Biological Chemistry, 283
Angelina Bilate, J. Lafaille (2012)
Induced CD4+Foxp3+ regulatory T cells in immune tolerance.Annual review of immunology, 30
Craig Maynard, L. Harrington, K. Janowski, J. Oliver, C. Zindl, A. Rudensky, C. Weaver (2007)
Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3− precursor cells in the absence of interleukin 10Nature Immunology, 8
Rui Wang, Jianghai Zhu, Xianchi Dong, Minlong Shi, Chafen Lu, T. Springer (2012)
GARP regulates the bioavailability and activation of TGFβMolecular Biology of the Cell, 23
Peter Kavsak, R. Rasmussen, Carrie Causing, S. Bonni, Hai-qing Zhu, G. Thomsen, J. Wrana (2000)
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation.Molecular cell, 6 6
M. Veldhoen, R. Hocking, R. Flavell, B. Stockinger (2006)
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain diseaseNature Immunology, 7
Lili Xu, A. Kitani, W. Strober (2010)
Molecular Mechanisms Regulating TGF-β-Induced Foxp3 ExpressionMucosal immunology, 3
S. Kang, Hyung Lim, O. Andrisani, H. Broxmeyer, Chang Kim (2007)
Vitamin A Metabolites Induce Gut-Homing FoxP3+ Regulatory T Cells1The Journal of Immunology, 179
Liang Zhou, I. Ivanov, R. Spolski, Roy Min, K. Shenderov, Takeshi Egawa, D. Levy, W. Leonard, D. Littman (2007)
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathwaysNature Immunology, 8
Jiangwen Zhu, K. Motejlek, Denan Wang, K. Zang, A. Schmidt, L. Reichardt (2002)
beta8 integrins are required for vascular morphogenesis in mouse embryos.Development, 129 12
E. Volpe, N. Servant, Raphaël Zollinger, S. Bogiatzi, P. Hupé, E. Barillot, V. Soumelis (2008)
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responsesNature Immunology, 9
Transforming Growth Factor (cid:2) -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth (cid:1) †
N. Wilson, K. Boniface, J. Chan, Brent McKenzie, W. Blumenschein, J. Mattson, B. Basham, Kathleen Smith, Taiying Chen, F. Morel, J. Lecron, R. Kastelein, D. Cua, T. Mcclanahan, E. Bowman, R. Malefyt (2007)
Development, cytokine profile and function of human interleukin 17–producing helper T cellsNature Immunology, 8
N. Kaminski, J. Allard, J. Pittet, F. Zuo, M. Griffiths, David Morris, X. Huang, D. Sheppard, R. Heller (2000)
Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis.Proceedings of the National Academy of Sciences of the United States of America, 97 4
D. Mucida, M. Husain, Sawako Muroi, F. Wijk, Ryo Shinnakasu, Y. Naoe, B. Reis, Yujun Huang, F. Lambolez, Michael Docherty, A. Attinger, J. Shui, Gisen Kim, C. Lena, S. Sakaguchi, Chizuko Miyamoto, Peng Wang, K. Atarashi, Yunji Park, T. Nakayama, K. Honda, W. Ellmeier, M. Kronenberg, I. Taniuchi, H. Cheroutre (2013)
Transcriptional Reprogramming of Mature CD4+ T helper Cells generates distinct MHC class II-restricted Cytotoxic T LymphocytesNature immunology, 14
Victoria Heath, E. Murphy, C. Crain, M. Tomlinson, A. O’Garra (2000)
TGF‐β1 down‐regulates Th2 development and results in decreased IL‐4‐induced STAT6 activation and GATA‐3 expressionEuropean Journal of Immunology, 30
M. Benson, Karina Pino-Lagos, M. Rosemblatt, R. Noelle (2007)
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulationThe Journal of Experimental Medicine, 204
A. Nakao, S. Miike, M. Hatano, K. Okumura, T. Tokuhisa, C. Ra, I. Iwamoto (2000)
Blockade of Transforming Growth Factor β/Smad Signaling in T Cells by Overexpression of Smad7 Enhances Antigen-Induced Airway Inflammation and Airway ReactivityThe Journal of Experimental Medicine, 192
A. Cunha, H. Weiner (2011)
Induction of Immunological Tolerance by Oral Anti-CD3Clinical and Developmental Immunology, 2012
Renee Robb, K. Lineburg, R. Kuns, Yana Wilson, Neil Raffelt, S. Olver, A. Varelias, Kylie Alexander, Bianca Teal, T. Sparwasser, G. Hammerling, K. Markey, M. Koyama, A. Clouston, C. Engwerda, G. Hill, K. Macdonald (2012)
Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.Blood, 119 24
M. Kudo, A. Melton, Chun Chen, M. Engler, Katherine Huang, X. Ren, Yanli Wang, X. Bernstein, John Li, K. Atabai, Xiaozhu Huang, D. Sheppard (2012)
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contractionNature medicine, 18
S. Cambier, Stephanie Gline, D. Mu, Rodney Collins, J. Araya, G. Dolganov, S. Einheber, N. Boudreau, S. Nishimura (2005)
Integrin αvβ8-Mediated Activation of Transforming Growth Factor-β by Perivascular Astrocytes: An Angiogenic Control SwitchAmerican Journal of Pathology, 166
N. Henderson, Thomas Arnold, Y. Katamura, Marilyn Giacomini, J. Rodriguez, J. McCarty, A. Pellicoro, Elisabeth Raschperger, C. Betsholtz, P. Ruminski, D. Griggs, M. Prinsen, J. Maher, J. Iredale, A. Lacy-Hulbert, R. Adams, D. Sheppard (2013)
Selective αv integrin depletion identifies a core, targetable molecular pathway that regulates fibrosis across solid organsNature medicine, 19
S. Ribeiro, M. Poczatek, S. Schultz‐Cherry, M. Villain, J. Murphy-Ullrich (1999)
The Activation Sequence of Thrombospondin-1 Interacts with the Latency-associated Peptide to Regulate Activation of Latent Transforming Growth Factor-β*The Journal of Biological Chemistry, 274
M. Fantini, A. Rizzo, D. Fina, R. Caruso, M. Sarra, C. Stolfi, C. Becker, T. Macdonald, F. Pallone, M. Neurath, G. Monteleone (2009)
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.Gastroenterology, 136 4
D. Kaplan, Ming Li, Matthew Jenison, W. Shlomchik, R. Flavell, M. Shlomchik (2007)
Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cellsThe Journal of Experimental Medicine, 204
M. Travis, B. Reizis, A. Melton, E. Masteller, Q. Tang, J. Proctor, Yanli Wang, X. Bernstein, Xiaozhu Huang, L. Reichardt, J. Bluestone, D. Sheppard (2007)
Loss of integrin αvβ8 on dendritic cells causes autoimmunity and colitis in miceNature, 449
C. Colarossi, Yan Chen, H. Obata, V. Jurukovski, L. Fontana, B. Dabovic, D. Rifkin (2010)
Growth Factors , Cytokines , Cell Cycle Molecules Lung Alveolar Septation Defects in Ltbp-3-Null Mice
Y. Laouar, F. Sutterwala, L. Gorelik, R. Flavell (2005)
Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γNature Immunology, 6
S. Zheng, Juhua Wang, Pu Wang, J. Gray, D. Horwitz (2007)
IL-2 Is Essential for TGF-β to Convert Naive CD4+CD25− Cells to CD25+Foxp3+ Regulatory T Cells and for Expansion of These Cells1The Journal of Immunology, 178
S. Ludbrook, S. Barry, C. Delves, C. Horgan (2003)
The integrin alphavbeta3 is a receptor for the latency-associated peptides of transforming growth factors beta1 and beta3.The Biochemical journal, 369 Pt 2
A. Lacy-Hulbert, Aileen Smith, Hamid Tissire, M. Barry, D. Crowley, R. Bronson, J. Roes, J. Savill, R. Hynes (2007)
Ulcerative colitis and autoimmunity induced by loss of myeloid αv integrinsProceedings of the National Academy of Sciences, 104
R. Dinesh, B. Skaggs, A. Cava, B. Hahn, Ram Singh (2010)
CD8+ Tregs in lupus, autoimmunity, and beyond.Autoimmunity reviews, 9 8
A. O’Garra, L. Gabryšová, H. Spits (2011)
Quantitative events determine the differentiation and function of helper T cellsNature Immunology, 12
T. Takimoto, Y. Wakabayashi, T. Sekiya, N. Inoue, R. Morita, K. Ichiyama, Reiko Takahashi, M. Asakawa, Go Muto, Tomoaki Mori, Eiichi Hasegawa, S. Shizuya, T. Hara, M. Nomura, A. Yoshimura (2010)
Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 DevelopmentThe Journal of Immunology, 185
S. Schultz‐Cherry, V. Hinshaw (1996)
Influenza virus neuraminidase activates latent transforming growth factor betaJournal of Virology, 70
Yongzhong Liu, Pin Zhang, Jun Li, A. Kulkarni, S. Perruche, Wanjun Chen (2008)
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cellsNature Immunology, 9
M. Shull, I. Ormsby, A. Kier, S. Pawlowski, R. Diebold, M. Yin, Ruth Allen, C. Sidman, G. Proetzel, D. Calvin, Nikki Annunziata, T. Doetschman (1992)
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory diseaseNature, 359
G. Martinez, Zhengmao Zhang, J. Reynolds, Shinya Tanaka, Yeonseok Chung, Ting Liu, E. Robertson, Xia Lin, Xin-Hua Feng, C. Dong (2010)
Smad2 Positively Regulates the Generation of Th17 Cells*The Journal of Biological Chemistry, 285
Sangwon Kim, W. Xiang, C. Kwak, Yi Yang, X. Lin, M. Ota, U. Sarpel, D. Rifkin, R. Xu, D. Littman (2013)
GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine MucosaScience, 340
J. Annes, J. Munger, D. Rifkin (2003)
Making sense of latent TGFβ activationJournal of Cell Science, 116
M. Chen, Bo-Shiun Yan, D. Kozoriz, H. Weiner (2009)
Novel CD8+ Treg suppress EAE by TGF‐β‐ and IFN‐γ‐dependent mechanismsEuropean Journal of Immunology, 39
P. Aluwihare, Z. Mu, Zhicheng Zhao, Dawen Yu, P. Weinreb, G. Horan, S. Violette, J. Munger (2009)
Mice that lack activity of αvβ6- and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null miceJournal of Cell Science, 122
H. Vliet, E. Nieuwenhuis (2007)
IPEX as a Result of Mutations in FOXP3Clinical and Developmental Immunology, 2007
Weibin Shi, Chuanxi Sun, B. He, Wencheng Xiong, Xingming Shi, Dachun Yao, Xu Cao (2004)
GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptorThe Journal of Cell Biology, 164
J. Munger, J. Harpel, P. Gleizes, R. Mazzieri, I. Nunes, D. Rifkin (1997)
Latent transforming growth factor-beta: structural features and mechanisms of activation.Kidney international, 51 5
J. Letterio, A. Geiser, A. Kulkarni, H. Dang, L. Kong, T. Nakabayashi, C. Mackall, R. Gress, A. Roberts (1996)
Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression.The Journal of clinical investigation, 98 9
N. Malhotra, E. Robertson, Joonsoo Kang (2010)
SMAD2 Is Essential for TGFβ-mediated Th17 Cell Generation*The Journal of Biological Chemistry, 285
Ye Zheng, S. Josefowicz, A. Chaudhry, Xiao Peng, K. Forbush, A. Rudensky (2010)
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fateNature, 463
V. Dardalhon, A. Awasthi, H. Kwon, George Galileos, Wenda Gao, R. Sobel, M. Mitsdoerffer, T. Strom, W. Elyaman, I. Ho, S. Khoury, M. Oukka, V. Kuchroo (2008)
Interleukin 4 inhibits TGF-β-induced-Foxp3+T cells and generates, in combination with TGF-β, Foxp3− effector T cells that produce interleukins 9 and 10Nature immunology, 9
T. Takimoto, Y. Wakabayashi, T. Sekiya, N. Inoue, R. Morita, K. Ichiyama, Reiko Takahashi, M. Asakawa, Go Muto, Tomoaki Mori, Eiichi Hasegawa, S. Shizuya, T. Hara, M. Nomura, A. Yoshimura (2011)
Correction: Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 DevelopmentThe Journal of Immunology, 186
J. Breuss, J. Gallo, H. DeLisser, I. Klimanskaya, H. Folkesson, J. Pittet, S. Nishimura, K. Aldape, D. Landers, W. Carpenter (1995)
Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling.Journal of cell science, 108 ( Pt 6)
D. Morris, Xiaozhu Huang, N. Kaminski, Yanli Wang, S. Shapiro, G. Dolganov, A. Glick, D. Sheppard (2003)
Loss of integrin αvβ6-mediated TGF-β activation causes Mmp12-dependent emphysemaNature, 422
S. Crawford, V. Stellmach, J. Murphy-Ullrich, S. Ribeiro, J. Lawler, R. Hynes, G. Boivin, N. Bouck (1998)
Thrombospondin-1 Is a Major Activator of TGF-β1 In VivoCell, 93
M. Barcellos-Hoff, R. Derynck, M Tsang, J. Weatherbee (1994)
Transforming growth factor-beta activation in irradiated murine mammary gland.The Journal of clinical investigation, 93 2
M. Coleman, Darren Ruane, B. Moran, P. Dunne, J. Keane, K. Mills (2013)
Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells.American journal of respiratory cell and molecular biology, 48 6
L. Gorelik, P. Fields, R. Flavell (2000)
Cutting Edge: TGF-β Inhibits Th Type 2 Development Through Inhibition of GATA-3 ExpressionThe Journal of Immunology, 165
M. Kuwahara, M. Yamashita, K. Shinoda, Soichi Tofukuji, A. Onodera, Ryo Shinnakasu, S. Motohashi, H. Hosokawa, D. Tumes, C. Iwamura, V. Lefebvre, T. Nakayama (2012)
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses TH2 differentiationNature Immunology, 13
S. Josefowicz, R. Niec, Hye Kim, P. Treuting, T. Chinen, Ye Zheng, D. Umetsu, A. Rudensky (2012)
Extrathymically generated regulatory T cells control mucosal TH2 inflammationNature, 482
Minlong Shi, Jianghai Zhu, Rui Wang, Xing Chen, L. Mi, T. Walz, T. Springer (2011)
Latent TGF-β structure and activationNature, 474
D. Tran, J. Andersson, Rui Wang, H. Ramsey, D. Unutmaz, E. Shevach (2009)
GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3+ regulatory T cellsProceedings of the National Academy of Sciences, 106
Ming Li, Y. Wan, R. Flavell (2007)
T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation.Immunity, 26 5
R. Ramalingam, C. Larmonier, R. Thurston, M. Midura-Kiela, S. Zheng, F. Ghishan, P. Kiela (2012)
Dendritic Cell-Specific Disruption of TGF-β Receptor II Leads to Altered Regulatory T Cell Phenotype and Spontaneous Multiorgan AutoimmunityThe Journal of Immunology, 189
Wei Hu, T. Troutman, R. Edukulla, C. Pasare (2011)
Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment.Immunity, 35 6
I. Agache, C. Ciobanu, Costel Agache, M. Anghel (2010)
Increased serum IL-17 is an independent risk factor for severe asthma.Respiratory medicine, 104 8
A. Awasthi, Yijun Carrier, J. Peron, E. Bettelli, M. Kamanaka, R. Flavell, V. Kuchroo, M. Oukka, H. Weiner (2007)
A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cellsNature Immunology, 8
E. Bettelli, Yijun Carrier, Wenda Gao, T. Korn, T. Strom, M. Oukka, H. Weiner, V. Kuchroo (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsNature, 441
P. Wipff, D. Rifkin, J. Meister, B. Hinz (2007)
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrixThe Journal of Cell Biology, 179
S. Schultz‐Cherry, Hui Chen, D. Mosher, T. Misenheimer, H. Krutzsch, D. Roberts, J. Murphy-Ullrich (1995)
Regulation of Transforming Growth Factor-β Activation by Discrete Sequences of Thrombospondin 1 (*)The Journal of Biological Chemistry, 270
M. McGeachy, K. Bak-Jensen, Yi Chen, C. Tato, W. Blumenschein, T. Mcclanahan, D. Cua (2007)
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathologyNature Immunology, 8
Wenming Peng, L. Maintz, J. Allam, N. Novak (2013)
Attenuated TGF‐β1 responsiveness of dendritic cells and their precursors in atopic dermatitisEuropean Journal of Immunology, 43
J. Kang, Cheng Liu, R. Derynck (2009)
New regulatory mechanisms of TGF-beta receptor function.Trends in cell biology, 19 8
J. Coombes, K. Siddiqui, C. Arancibia-Cárcamo, J. Hall, Cheng-Ming Sun, Y. Belkaid, F. Powrie (2007)
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanismThe Journal of Experimental Medicine, 204
J. Sung, Jack Lin, J. Gorham (2003)
CD28 co-stimulation regulates the effect of transforming growth factor-beta1 on the proliferation of naïve CD4+ T cells.International immunopharmacology, 3 2
K. Ghoreschi, A. Laurence, Xiang-Ping Yang, C. Tato, M. McGeachy, J. Konkel, Haydeé Ramos, Lai Wei, Todd Davidson, N. Bouladoux, J. Grainger, Qian Chen, Y. Kanno, W. Watford, Hong-Wei Sun, G. Eberl, E. Shevach, Y. Belkaid, D. Cua, Wanjun Chen, J. O’Shea (2010)
Generation of Pathogenic Th17 Cells in the Absence of TGF-β SignalingNature, 467
D. Mu, S. Cambier, L. Fjellbirkeland, J. Baron, J. Munger, H. Kawakatsu, D. Sheppard, V. Broaddus, S. Nishimura (2002)
The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1The Journal of Cell Biology, 157
V. Kaartinen, J. Voncken, C. Shuler, D. Warburton, Dingfang Bu, N. Heisterkamp, J. Groffen (1995)
Abnormal lung development and cleft palate in mice lacking TGF–β3 indicates defects of epithelial–mesenchymal interactionNature Genetics, 11
J. Schoenborn, Christopher Wilson (2007)
Regulation of interferon-gamma during innate and adaptive immune responses.Advances in immunology, 96
P. Soroosh, T. Doherty, W. Duan, A. Mehta, Heonsik Choi, Yan Adams, Z. Mikulski, Naseem Khorram, P. Rosenthal, D. Broide, M. Croft (2013)
Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway toleranceThe Journal of Experimental Medicine, 210
P. Gleizes, J. Munger, I. Nunes, J. Harpel, R. Mazzieri, I. Noguera, D. Rifkin (1997)
TGF‐β Latency: Biological Significance and Mechanisms of ActivationSTEM CELLS, 15
J. Saharinen, J. Keski‐oja (2000)
Specific Sequence Motif of 8-Cys Repeats of TGF-β Binding Proteins, LTBPs, Creates a Hydrophobic Interaction Surface for Binding of Small Latent TGF-βMolecular Biology of the Cell, 11
J. Edwards, H. Fujii, Ang Zhou, J. Creemers, D. Unutmaz, E. Shevach (2013)
Regulation of the Expression of GARP/Latent TGF-β1 Complexes on Mouse T Cells and Their Role in Regulatory T Cell and Th17 DifferentiationThe Journal of Immunology, 190
(2012)
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
I. Kleiter, Jian Song, D. Lukas, Maruf Hasan, B. Neumann, Andrew Croxford, X. Pedre, N. Hövelmeyer, Nir Yogev, A. Mildner, M. Prinz, Elena Wiese, K. Reifenberg, S. Bittner, H. Wiendl, L. Steinman, C. Becker, U. Bogdahn, M. Neurath, A. Steinbrecher, A. Waisman (2010)
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitisBrain, 133
C. Wilhelm, K. Hirota, B. Stieglitz, J. Snick, M. Tolaini, K. Lahl, T. Sparwasser, H. Helmby, B. Stockinger (2011)
Interleukin 9 fate reporter reveals induction of innate IL-9 response in lung inflammationNature immunology, 12
Lili Xu, A. Kitani, C. Stuelten, G. McGrady, I. Fuss, W. Strober (2010)
Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I.Immunity, 33 3
J. Polansky, Karsten Kretschmer, Jennifer Freyer, S. Floess, A. Garbe, U. Baron, S. Olek, A. Hamann, H. Boehmer, J. Huehn (2008)
DNA methylation controls Foxp3 gene expressionEuropean Journal of Immunology, 38
N. Manel, D. Unutmaz, D. Littman (2008)
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγtNature Immunology, 9
Shigetoshi Kobayashi, Kunihiro Yoshida, Jerrold Ward, J. Letterio, G. Longenecker, Linda Yaswen, B. Mittleman, E. Mozes, A. Roberts, S. Karlsson, A. Kulkarni (1999)
Beta 2-microglobulin-deficient background ameliorates lethal phenotype of the TGF-beta 1 null mouse.Journal of immunology, 163 7
A. Melton, Samantha Bailey-bucktrout, M. Travis, B. Fife, J. Bluestone, D. Sheppard (2010)
Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice.The Journal of clinical investigation, 120 12
M. Brunkow, E. Jeffery, K. Hjerrild, B. Paeper, L. Clark, Sue-Ann Yasayko, J. Wilkinson, D. Galas, S. Ziegler, F. Ramsdell (2001)
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseNature Genetics, 27
H. Hayashi, S. Abdollah, Yubin Qiu, Jie Cai, Yong-Yao Xu, B. Grinnell, M. Richardson, J. Topper, M. Gimbrone, J. Wrana, D. Falb (1997)
The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ SignalingCell, 89
C. Mayer, S. Floess, A. Baru, K. Lahl, J. Huehn, T. Sparwasser (2011)
CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activityEuropean Journal of Immunology, 41
H. Ishigame, Munir Mosaheb, Shomyseh Sanjabi, R. Flavell (2013)
Truncated Form of TGF-βRII, But Not Its Absence, Induces Memory CD8+ T Cell Expansion and Lymphoproliferative Disorder in MiceThe Journal of Immunology, 190
Ming Li, Shomyseh Sanjabi, R. Flavell (2006)
Transforming Growth Factor-β Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent MechanismsImmunity, 25
Johannes, Nancy GIUElT, L. LucY, D. Sheppard, Robert PY’IELA (1993)
Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 41
G. Martinez, Zhengmao Zhang, Yeonseok Chung, J. Reynolds, Xia Lin, A. Jetten, Xin-Hua Feng, C. Dong (2009)
Smad3 Differentially Regulates the Induction of Regulatory and Inflammatory T Cell Differentiation*The Journal of Biological Chemistry, 284
J. Fontenot, J. Rasmussen, L. Williams, James Dooley, A. Farr, A. Rudensky (2005)
Regulatory T cell lineage specification by the forkhead transcription factor foxp3.Immunity, 22 3
T. Korn, E. Bettelli, M. Oukka, V. Kuchroo (2009)
IL-17 and Th17 Cells.Annual review of immunology, 27
Y. Asano, H. Ihn, K. Yamane, M. Jinnin, K. Tamaki (2006)
Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal FibroblastsAmerican Journal of Pathology, 168
P. Lucas, Seong-Jin Kim, S. Melby, R. Gress (2000)
Disruption of T Cell Homeostasis in Mice Expressing a T Cell–Specific Dominant Negative Transforming Growth Factor β II ReceptorThe Journal of Experimental Medicine, 191
B. Reis, Aneta Rogoz, F. Costa-Pinto, I. Taniuchi, D. Mucida (2012)
Mutual expression of Runx3 and ThPOK regulates intestinal CD4+ T cell immunityNature immunology, 14
Michael Shaw, N. Kamada, Yun-Gi Kim, G. Núñez (2012)
Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestineThe Journal of Experimental Medicine, 209
J. Gorham, M. Guler, D. Fenoglio, U. Gubler, K. Murphy (1998)
Low Dose TGF-β Attenuates IL-12 Responsiveness in Murine Th CellsThe Journal of Immunology
I. Gutcher, Moses Donkor, Q. Ma, A. Rudensky, R. Flavell, Ming Li (2011)
Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation.Immunity, 34 3
Hua‐Chen Chang, S. Sehra, R. Goswami, W. Yao, Qing Yu, Gretta Stritesky, R. Jabeen, Carl McKinley, Ayele-Nati Ahyi, Ling Han, Evelyn Nguyen, M. Robertson, N. Perumal, R. Tepper, S. Nutt, M. Kaplan (2010)
The transcription factor PU.1 is required for the development of interleukin 9-producing T cells and allergic inflammationNature immunology, 11
L. Fahlén, S. Read, L. Gorelik, S. Hurst, R. Coffman, R. Flavell, F. Powrie (2005)
T cells that cannot respond to TGF-β escape control by CD4+CD25+ regulatory T cellsThe Journal of Experimental Medicine, 201
Byung-Gyu Kim, Cuiling Li, Wenhui Qiao, M. Mamura, Barbara Kasperczak, M. Anver, L. Wolfraim, Suntaek Hong, E. Mushinski, M. Potter, Seong-Jin Kim, Xin-Yuan Fu, C. Deng, J. Letterio (2006)
Smad4 signalling in T cells is required for suppression of gastrointestinal cancerNature, 441
J. Annes, Yan Chen, J. Munger, Daniel Rifkin (2004)
Integrin αVβ6-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1The Journal of Cell Biology, 165
Rui Wang, L. Kozhaya, Frances Mercer, Alka Khaitan, H. Fujii, D. Unutmaz (2009)
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cellsProceedings of the National Academy of Sciences, 106
Cheng-Ming Sun, J. Hall, J. Hall, R. Blank, N. Bouladoux, M. Oukka, J. Mora, Y. Belkaid (2007)
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidThe Journal of Experimental Medicine, 204
J. Munger, Xi‐Ping Huang, H. Kawakatsu, M. Griffiths, S. Dalton, Jingjing Wu, J. Pittet, N. Kaminski, C. Garat, M. Matthay, D. Rifkin, D. Sheppard (1999)
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.Cell, 96 3
P. Knight, S. Wright, Jeremy Brown, Xiaozhu Huang, D. Sheppard, H. Miller (2002)
Enteric Expression of the Integrin αvβ6 Is Essential for Nematode-Induced Mucosal Mast Cell Hyperplasia and Expression of the Granule Chymase, Mouse Mast Cell Protease-1American Journal of Pathology, 161
Takatoku Oida, H. Weiner (2010)
TGF-β Induces Surface LAP Expression on Murine CD4 T Cells Independent of Foxp3 InductionPLoS ONE, 5
Annual Review of Immunology – Unpaywall
Published: Dec 6, 2013
Access the full text.
Sign up today, get DeepDyve free for 14 days.