Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic... Intensive Care Med (2008) 34:783–785 ERRATUM DOI 10.1007/s00134-008-1040-9 R. Phillip Dellinger Surviving Sepsis Campaign: Mitchell M. Levy Jean M. Carlet International guidelines for management Julian Bion Margaret M. Parker of severe sepsis and septic shock: 2008 Roman Jaeschke Konrad Reinhart Derek C. Angus Christian Brun-Buisson Richard Beale Thierry Calandra Jean-Francois Dhainaut Herwig Gerlach Maurene Harvey John J. Marini John Marshall Marco Ranieri Graham Ramsay Jonathan Sevransky B. Taylor Thompson Sean Townsend Jeffrey S. Vender Janice L. Zimmerman Jean-Louis Vincent R. Jaeschke Published online: 29 February 2008 McMaster University, © Springer-Verlag 2008 Hamilton, Canada K. Reinhart The online version of the original can be found at Friedrich-Schiller-University of Jena, http://dx.doi.org/10.1007/s00134-007-0934-2. Jena, Germany D. C. Angus R. P. Dellinger () University of Pittsburgh, Cooper University Hospital, Pittsburgh PA, USA One Cooper Plaza, 393 Dorrance, Camden 08103, NJ, USA C. Brun-Buisson e-mail: [email protected] Hopital Henri Mondor, Créteil, France M. M. Levy · S. Townsend R. Beale Rhode Island Hospital, Guy’s and St Thomas’ Hospital Trust, Providence RI, USA London, UK J. M. Carlet T. Calandra Hospital Saint-Joseph, Centre Hospitalier Universitaire Vaudois, Paris, France Lausanne, Switzerland J. Bion J.-F. Dhainaut Birmingham University, French Agency for Evaluation of Research and Higher Education, Birmingham, UK Paris, France M. M. Parker H. Gerlach SUNY at Stony Brook, Vivantes-Klinikum Neukoelln, Stony Brook NY, USA Berlin, Germany 784 M. Harvey J. Sevransky Consultants in Critical Care, Inc., The Johns Hopkins University School Glenbrook NV, USA of Medicine, Baltimore MD, USA J. J. Marini B. T. Thompson University of Minnesota, Massachusetts General Hospital, St. Paul MN, USA Boston MA, USA J. Marshall J. S. Vender St. Michael’s Hospital, Evanston Northwestern Healthcare, Toronto, Canada Evanston IL, USA M. Ranieri J. L. Zimmerman Università di Torino, The Methodist Hospital, Torino, Italy Houston TX, USA G. Ramsay J.-L. Vincent West Hertfordshire Health Trust, Erasme University Hospital, Hemel Hempstead, UK Brussels, Belgium In the article by Dellinger et al., published in the January Scheme 1 Continued 2008 issue of Intensive Care Medicine, the addition of two Hemodynamic variables tables, labeled Scheme 1 and Scheme 2, and subsequent Arterial hypotension (SBP < 90 mmHg, MAP < 70 mmHg, or text changes should appear as follows. an SBP decrease > 40 mmHg in adults or < 2 SD below normal for age) On page 19, the first sentence in the Methods section Organ dysfunction variables should read as follows. Arterial hypoxemia (PaO /FIO < 300) 2 2 Acute oliguria (urine output < 0.5 ml/kg hr for at least 2 hrs Sepsis is defined as infection plus systemic manifesta- despite adequate fluid resuscitation) tions of infection (Scheme 1) (12). Creatinine increase > 0.5 mg/dL or 44.2 micromol/L Coagulation abnormalities (INR > 1.5 or a PTT > 60 secs) On page 19, the first full sentence in the second column Ileus (absent bowel sounds) should read as follows. −1 Thrombocytopenia (platelet count < 100,000 µL ) An example of typical thresholds for identification of Hyperbilirubinemia (plasma total bilirubin > 4 mg/dL or 70 micromol/L) severe sepsis is shown in Scheme 2 (12, 13). Tissue perfusion variables Scheme 1 and Scheme 2, which were not included in the Hyperlactatemia (> upper limit of lab normal) article, appear as follows. Decreased capillary refill or mottling Diagnostic criteria for sepsis in the pediatric population are signs and symptoms of inflammation plus infection with hyper- or hypo- thermia (rectal temperature > 38.5 or < 35 C), tachycardia (may be Scheme 1 Diagnostic criteria for sepsis. WBC, white blood cell; absent in hypothermic patients), and at least one of the following SBP, systolic blood pressure; MAP, mean arterial blood pressure; indications of altered organ function: altered mental status, hypox- INR, international normalized ration; aPTT, activated partial throm- emia, increased serum lactate level or bounding pulses. boplastin time Infection, documented or suspected, and some of the following: Adapted from Levy MM, Fink MP, Marshall JC, et al: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions General variables Conference. Crit Care Med 2003; 31:1250-1256 Fever (> 38.3 C) Hypothermia (core temperature < 36 C) −1 Heart rate > 90 min or > 2 SD above the Scheme 2 normal value for age Severe Sepsis = Sepsis-Induced Tissue Hypoperfusion or Organ Tachypnea Dysfunction (any of the following thought to be due to the infection) Altered mental status Significant edema or positive fluid balance (> 20 mL/kg over • Sepsis induced hypotension 24 hrs) • Lactate > upper limits lab normal Hyperglycemia (plasma glucose > 140 mg/dL or 7.7 mmol/L) • Urine output < 0.5 ml/kg hr for > 2 hrs despite adequate fluid in the absence of diabetes resuscitation Inflammatory variables −1 • ALI with PaO2/FIO2 < 250 in the absence of pneumonia as in- Leukocytosis (WBC count > 12,000 µL ) −1 fection source Leukopenia (WBC count < 4000 µL ) • ALI with PaO2/FIO2 < 200 in the presence of pneumonia as in- Normal WBC count with > 10% immature forms fection source Plasma C-reactive protein > 2 SD above the normal value • Creatinine > 2.0 mg/dl (176.8 micromol/L) Plasma procalcitonin > 2 SD above the normal value • Bilirubin > 2 mg/dl (34.2 micromol/L) 785 • Platelet count < 100,000 The following errors appeared in Table 5. • Coagulopathy (INR > 1.5) 1. Under Blood product administration recommenda- Adapted from Levy, MM, Fink MP, Marshall JC, et al: tions: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Fresh frozen plasma recommendation circle should be Definitions Conference. Intensive Care Medicine 2003; open 29:530–538. ACCP/SCCM Consensus Conference Com- Antithrombin recommendation circle should be closed mittee: American College of Chest Physicians/Society of Platelet recommendation circle should be open Critical Care Medicine Consensus Conference: Defini- 2. Under Glucose control: tions for sepsis and organ failure and guidelines for the Aim to keep blood glucose recommendation use of innovative therapies in sepsis. Crit Care Med 1992; < 150 mg/dL (8.3 mmol/L) should have an open 20:864–874 circle On page 21, the sentence in the second full paragraph On page 17 the Indian Society of Critical Care Medicine should read as follows. and the World Federation of Critical Care Nurses should be added to the list of sponsoring organizations who did The committee assessed whether the desirable effects not participate formally in the revision process. of adherence will outweigh the undesirable effects, and the strength of a recommendation reflects the group’s degree of confidence in that assessment (Table 2). The authors regret the errors. References 1. Dellinger RP, Levy MM, Carlet JM, et al. (2008) Surviving Sepsis Cam- paign: International guidelines for management of severe sepsis and septic shock. Intensive Care Med 34:17–60 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Intensive Care Medicine Pubmed Central

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

Download PDF
3 pages

Loading next page...
 
/lp/pubmed-central/surviving-sepsis-campaign-international-guidelines-for-management-of-Ua50HC62PH

References (1)

Publisher
Pubmed Central
Copyright
© Springer-Verlag 2008
ISSN
0342-4642
eISSN
1432-1238
DOI
10.1007/s00134-008-1040-9
Publisher site
See Article on Publisher Site

Abstract

Intensive Care Med (2008) 34:783–785 ERRATUM DOI 10.1007/s00134-008-1040-9 R. Phillip Dellinger Surviving Sepsis Campaign: Mitchell M. Levy Jean M. Carlet International guidelines for management Julian Bion Margaret M. Parker of severe sepsis and septic shock: 2008 Roman Jaeschke Konrad Reinhart Derek C. Angus Christian Brun-Buisson Richard Beale Thierry Calandra Jean-Francois Dhainaut Herwig Gerlach Maurene Harvey John J. Marini John Marshall Marco Ranieri Graham Ramsay Jonathan Sevransky B. Taylor Thompson Sean Townsend Jeffrey S. Vender Janice L. Zimmerman Jean-Louis Vincent R. Jaeschke Published online: 29 February 2008 McMaster University, © Springer-Verlag 2008 Hamilton, Canada K. Reinhart The online version of the original can be found at Friedrich-Schiller-University of Jena, http://dx.doi.org/10.1007/s00134-007-0934-2. Jena, Germany D. C. Angus R. P. Dellinger () University of Pittsburgh, Cooper University Hospital, Pittsburgh PA, USA One Cooper Plaza, 393 Dorrance, Camden 08103, NJ, USA C. Brun-Buisson e-mail: [email protected] Hopital Henri Mondor, Créteil, France M. M. Levy · S. Townsend R. Beale Rhode Island Hospital, Guy’s and St Thomas’ Hospital Trust, Providence RI, USA London, UK J. M. Carlet T. Calandra Hospital Saint-Joseph, Centre Hospitalier Universitaire Vaudois, Paris, France Lausanne, Switzerland J. Bion J.-F. Dhainaut Birmingham University, French Agency for Evaluation of Research and Higher Education, Birmingham, UK Paris, France M. M. Parker H. Gerlach SUNY at Stony Brook, Vivantes-Klinikum Neukoelln, Stony Brook NY, USA Berlin, Germany 784 M. Harvey J. Sevransky Consultants in Critical Care, Inc., The Johns Hopkins University School Glenbrook NV, USA of Medicine, Baltimore MD, USA J. J. Marini B. T. Thompson University of Minnesota, Massachusetts General Hospital, St. Paul MN, USA Boston MA, USA J. Marshall J. S. Vender St. Michael’s Hospital, Evanston Northwestern Healthcare, Toronto, Canada Evanston IL, USA M. Ranieri J. L. Zimmerman Università di Torino, The Methodist Hospital, Torino, Italy Houston TX, USA G. Ramsay J.-L. Vincent West Hertfordshire Health Trust, Erasme University Hospital, Hemel Hempstead, UK Brussels, Belgium In the article by Dellinger et al., published in the January Scheme 1 Continued 2008 issue of Intensive Care Medicine, the addition of two Hemodynamic variables tables, labeled Scheme 1 and Scheme 2, and subsequent Arterial hypotension (SBP < 90 mmHg, MAP < 70 mmHg, or text changes should appear as follows. an SBP decrease > 40 mmHg in adults or < 2 SD below normal for age) On page 19, the first sentence in the Methods section Organ dysfunction variables should read as follows. Arterial hypoxemia (PaO /FIO < 300) 2 2 Acute oliguria (urine output < 0.5 ml/kg hr for at least 2 hrs Sepsis is defined as infection plus systemic manifesta- despite adequate fluid resuscitation) tions of infection (Scheme 1) (12). Creatinine increase > 0.5 mg/dL or 44.2 micromol/L Coagulation abnormalities (INR > 1.5 or a PTT > 60 secs) On page 19, the first full sentence in the second column Ileus (absent bowel sounds) should read as follows. −1 Thrombocytopenia (platelet count < 100,000 µL ) An example of typical thresholds for identification of Hyperbilirubinemia (plasma total bilirubin > 4 mg/dL or 70 micromol/L) severe sepsis is shown in Scheme 2 (12, 13). Tissue perfusion variables Scheme 1 and Scheme 2, which were not included in the Hyperlactatemia (> upper limit of lab normal) article, appear as follows. Decreased capillary refill or mottling Diagnostic criteria for sepsis in the pediatric population are signs and symptoms of inflammation plus infection with hyper- or hypo- thermia (rectal temperature > 38.5 or < 35 C), tachycardia (may be Scheme 1 Diagnostic criteria for sepsis. WBC, white blood cell; absent in hypothermic patients), and at least one of the following SBP, systolic blood pressure; MAP, mean arterial blood pressure; indications of altered organ function: altered mental status, hypox- INR, international normalized ration; aPTT, activated partial throm- emia, increased serum lactate level or bounding pulses. boplastin time Infection, documented or suspected, and some of the following: Adapted from Levy MM, Fink MP, Marshall JC, et al: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions General variables Conference. Crit Care Med 2003; 31:1250-1256 Fever (> 38.3 C) Hypothermia (core temperature < 36 C) −1 Heart rate > 90 min or > 2 SD above the Scheme 2 normal value for age Severe Sepsis = Sepsis-Induced Tissue Hypoperfusion or Organ Tachypnea Dysfunction (any of the following thought to be due to the infection) Altered mental status Significant edema or positive fluid balance (> 20 mL/kg over • Sepsis induced hypotension 24 hrs) • Lactate > upper limits lab normal Hyperglycemia (plasma glucose > 140 mg/dL or 7.7 mmol/L) • Urine output < 0.5 ml/kg hr for > 2 hrs despite adequate fluid in the absence of diabetes resuscitation Inflammatory variables −1 • ALI with PaO2/FIO2 < 250 in the absence of pneumonia as in- Leukocytosis (WBC count > 12,000 µL ) −1 fection source Leukopenia (WBC count < 4000 µL ) • ALI with PaO2/FIO2 < 200 in the presence of pneumonia as in- Normal WBC count with > 10% immature forms fection source Plasma C-reactive protein > 2 SD above the normal value • Creatinine > 2.0 mg/dl (176.8 micromol/L) Plasma procalcitonin > 2 SD above the normal value • Bilirubin > 2 mg/dl (34.2 micromol/L) 785 • Platelet count < 100,000 The following errors appeared in Table 5. • Coagulopathy (INR > 1.5) 1. Under Blood product administration recommenda- Adapted from Levy, MM, Fink MP, Marshall JC, et al: tions: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Fresh frozen plasma recommendation circle should be Definitions Conference. Intensive Care Medicine 2003; open 29:530–538. ACCP/SCCM Consensus Conference Com- Antithrombin recommendation circle should be closed mittee: American College of Chest Physicians/Society of Platelet recommendation circle should be open Critical Care Medicine Consensus Conference: Defini- 2. Under Glucose control: tions for sepsis and organ failure and guidelines for the Aim to keep blood glucose recommendation use of innovative therapies in sepsis. Crit Care Med 1992; < 150 mg/dL (8.3 mmol/L) should have an open 20:864–874 circle On page 21, the sentence in the second full paragraph On page 17 the Indian Society of Critical Care Medicine should read as follows. and the World Federation of Critical Care Nurses should be added to the list of sponsoring organizations who did The committee assessed whether the desirable effects not participate formally in the revision process. of adherence will outweigh the undesirable effects, and the strength of a recommendation reflects the group’s degree of confidence in that assessment (Table 2). The authors regret the errors. References 1. Dellinger RP, Levy MM, Carlet JM, et al. (2008) Surviving Sepsis Cam- paign: International guidelines for management of severe sepsis and septic shock. Intensive Care Med 34:17–60

Journal

Intensive Care Medicine – Pubmed Central

Published: Feb 29, 2008

There are no references for this article.