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Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years

Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years Epidemiology/Population Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years Charles Faselis, Michael Doumas, Andreas Pittaras, Puneet Narayan, Jonathan Myers, Apostolos Tsimploulis, Peter Kokkinos Abstract—Aging, even in otherwise healthy subjects, is associated with declines in muscle mass, strength, and aerobic capacity. Older individuals respond favorably to exercise, suggesting that physical inactivity plays an important role in age-related functional decline. Conversely, physical activity and improved exercise capacity are associated with lower mortality risk in hypertensive individuals. However, the effect of exercise capacity in older hypertensive individuals has not been investigated extensively. A total of 2153 men with hypertension, aged ≥70 years (mean, 75±4) from the Washington, DC, and Palo Alto Veterans Affairs Medical Centers, underwent routine exercise tolerance testing. Peak workload was estimated in metabolic equivalents (METs). Fitness categories were established based on peak METs achieved, adjusted for age: very-low-fit, 2.0 to 4.0 METs (n=386); low-fit, 4.1 to 6.0 METs (n=1058); moderate-fit, 6.1 to 8.0 METs (n=495); high-fit >8.0 METs (n=214). Cox proportional hazard models were applied after adjusting for age, body mass index, race, cardiovascular disease, cardiovascular medications, and risk factors. All-cause mortality was quantified during a mean follow-up period of 9.0±5.5 years. There were http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Hypertension Wolters Kluwer Health

Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years

Kokkinos, Peter
Hypertension , Volume 64 (1) – Jul 1, 2014
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References (48)

Copyright
© 2014 American Heart Association, Inc.
ISSN
0194-911X
eISSN
1524-4563
DOI
10.1161/HYPERTENSIONAHA.114.03510
pmid
24821944
Publisher site
See Article on Publisher Site

Abstract

Epidemiology/Population Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years Charles Faselis, Michael Doumas, Andreas Pittaras, Puneet Narayan, Jonathan Myers, Apostolos Tsimploulis, Peter Kokkinos Abstract—Aging, even in otherwise healthy subjects, is associated with declines in muscle mass, strength, and aerobic capacity. Older individuals respond favorably to exercise, suggesting that physical inactivity plays an important role in age-related functional decline. Conversely, physical activity and improved exercise capacity are associated with lower mortality risk in hypertensive individuals. However, the effect of exercise capacity in older hypertensive individuals has not been investigated extensively. A total of 2153 men with hypertension, aged ≥70 years (mean, 75±4) from the Washington, DC, and Palo Alto Veterans Affairs Medical Centers, underwent routine exercise tolerance testing. Peak workload was estimated in metabolic equivalents (METs). Fitness categories were established based on peak METs achieved, adjusted for age: very-low-fit, 2.0 to 4.0 METs (n=386); low-fit, 4.1 to 6.0 METs (n=1058); moderate-fit, 6.1 to 8.0 METs (n=495); high-fit >8.0 METs (n=214). Cox proportional hazard models were applied after adjusting for age, body mass index, race, cardiovascular disease, cardiovascular medications, and risk factors. All-cause mortality was quantified during a mean follow-up period of 9.0±5.5 years. There were

Journal

Hypertension – Wolters Kluwer Health

Published: Jul 1, 2014

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