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Admission or Changes in Renal Function During Hospitalization for Worsening Heart Failure Predict Postdischarge Survival Results From the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF)

Admission or Changes in Renal Function During Hospitalization for Worsening Heart Failure Predict... Admission or Changes in Renal Function During Hospitalization for Worsening Heart Failure Predict Postdischarge Survival Results From the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) Liviu Klein, MD, MS; Barry M. Massie, MD; Jeffrey D. Leimberger, PhD; Christopher M. O’Connor, MD; Ileana L. Piña, MD; Kirkwood F. Adams, Jr, MD; Robert M. Califf, MD; Mihai Gheorghiade, MD; for the OPTIME-CHF Investigators Background—Admission measures of renal function (blood urea nitrogen [BUN], estimated glomerular filtration rate [eGFR]) in patients hospitalized for worsening heart failure are predictors of in-hospital outcomes. Less is known about the changes and relationships among these variables and the postdischarge survival rate. Methods and Results—In a retrospective analysis of 949 patients from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure, we investigated the relation between admission values and changes in 1 2 BUN and eGFR and rate of death by 60 days after discharge. On admission, median eGFR was 51 mL · min · 1.73 m 1 2 (interquartile range, 37 to 70 mL · min · 1.73 m ), and BUN was 25 mg/dL (interquartile range, 17 to 41 mg/dL). On 1 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation: Heart Failure Wolters Kluwer Health

Admission or Changes in Renal Function During Hospitalization for Worsening Heart Failure Predict Postdischarge Survival Results From the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF)

Gheorghiade, Mihai
Circulation: Heart Failure , Volume 1 (1) – May 1, 2008
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References (37)

ISSN
1941-3289
eISSN
1941-3297
DOI
10.1161/CIRCHEARTFAILURE.107.746933
pmid
19808267
Publisher site
See Article on Publisher Site

Abstract

Admission or Changes in Renal Function During Hospitalization for Worsening Heart Failure Predict Postdischarge Survival Results From the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) Liviu Klein, MD, MS; Barry M. Massie, MD; Jeffrey D. Leimberger, PhD; Christopher M. O’Connor, MD; Ileana L. Piña, MD; Kirkwood F. Adams, Jr, MD; Robert M. Califf, MD; Mihai Gheorghiade, MD; for the OPTIME-CHF Investigators Background—Admission measures of renal function (blood urea nitrogen [BUN], estimated glomerular filtration rate [eGFR]) in patients hospitalized for worsening heart failure are predictors of in-hospital outcomes. Less is known about the changes and relationships among these variables and the postdischarge survival rate. Methods and Results—In a retrospective analysis of 949 patients from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure, we investigated the relation between admission values and changes in 1 2 BUN and eGFR and rate of death by 60 days after discharge. On admission, median eGFR was 51 mL · min · 1.73 m 1 2 (interquartile range, 37 to 70 mL · min · 1.73 m ), and BUN was 25 mg/dL (interquartile range, 17 to 41 mg/dL). On 1

Journal

Circulation: Heart Failure – Wolters Kluwer Health

Published: May 1, 2008

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