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Acrodermatitis due to nutritional deficiency Kathryn A. Gehrig and James G.H. Dinulos Section of Dermatology, Dartmouth-Hitchcock Medical Purpose of review Center, Lebanon, New Hampshire, USA Nutritional deficiency is prevalent in developing countries but should also be considered Correspondence to James G.H. Dinulos, MD, Section in developed countries in the setting of genetic or acquired disease states. The skin is of Dermatology, Dartmouth-Hitchcock Clinic, One commonly involved and is often one of the first organs affected in nutritional deficiency, Medical Center Drive, Lebanon, NH 03756, USA Tel: +1 603 653 9400; fax: +1 603 650 0921; providing a key to the diagnosis. This article will review the most common nutritional e-mail: [email protected] deficiencies causing a periorificial and/or acrodermatitis: zinc deficiency, biotin Current Opinion in Pediatrics 2010, 22:107–112 deficiency, kwashiorkor, and essential fatty acid deficiency. Recent findings Whereas older literature has focused on the relationship among nutritional deficiency, malnutrition and poverty, recent research has identified additional patient populations that are at risk for developing nutritional deficiencies. These populations include premature infants, patients with long-term total parenteral nutrition, Crohn’s disease, cystic fibrosis, intestinal bypass procedures, chronic alcoholics, anorexia nervosa, and restrictive diets. Recent studies have also focused on further understanding the genetic
Current Opinion in Pediatrics – Wolters Kluwer Health
Published: Feb 1, 2010
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