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Projections of the precentral motor cortex and other cortical areas of the frontal lobe to the subthalamic nucleus in the monkey

Projections of the precentral motor cortex and other cortical areas of the frontal lobe to the... 221 33 33 3 4 K. Hartmann-von Monakow Prof. K. Akert H. Künzle Brain Research Institute University of Zürich August-Forel-Str. 1 CH-8029 Zürich Switzerland Summary Corticofugal projections were examined by means of the autoradiographic tracer method in 21 macaca fascicularis. The labeled material was injected into the main body representation areas of the precentral motor cortex and into various regions of Brodmann's areas 6, 8 and 9 of the frontal lobe. The ipsilateral subthalamic nucleus receives a moderately strong and somato-topically organized projection from Woolsey's precentral motor cortex. This projection is mainly restricted to the lateral moiety. The remaining nucleus is occupied by less intensive projections from premotor and prefrontal areas. It is concluded that the subthalamic nucleus is a convergence site of pallidal and corticomotor and frontal projections. Cortical afferents may exert an influence on the pallido-subthalamic-pallidal inhibitory feedback loop. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Experimental Brain Research Springer Journals

Projections of the precentral motor cortex and other cortical areas of the frontal lobe to the subthalamic nucleus in the monkey

Experimental Brain Research , Volume 33 (3) – Sep 1, 1978

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References (23)

Publisher
Springer Journals
Copyright
Copyright © 1978 by Springer-Verlag
Subject
Biomedicine; Neurosciences; Neurology
ISSN
0014-4819
eISSN
1432-1106
DOI
10.1007/BF00235561
Publisher site
See Article on Publisher Site

Abstract

221 33 33 3 4 K. Hartmann-von Monakow Prof. K. Akert H. Künzle Brain Research Institute University of Zürich August-Forel-Str. 1 CH-8029 Zürich Switzerland Summary Corticofugal projections were examined by means of the autoradiographic tracer method in 21 macaca fascicularis. The labeled material was injected into the main body representation areas of the precentral motor cortex and into various regions of Brodmann's areas 6, 8 and 9 of the frontal lobe. The ipsilateral subthalamic nucleus receives a moderately strong and somato-topically organized projection from Woolsey's precentral motor cortex. This projection is mainly restricted to the lateral moiety. The remaining nucleus is occupied by less intensive projections from premotor and prefrontal areas. It is concluded that the subthalamic nucleus is a convergence site of pallidal and corticomotor and frontal projections. Cortical afferents may exert an influence on the pallido-subthalamic-pallidal inhibitory feedback loop.

Journal

Experimental Brain ResearchSpringer Journals

Published: Sep 1, 1978

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