Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/springer-journals/antifungal-innate-immunity-recognition-and-inflammatory-networks-S0zNPLnXuX
References (87)
-
LY Ngo (2014)
Inflammatory monocytes mediate early and organ-specific innate defense during systemic candidiasisJ Infect Dis, 209
-
TM Hohl (2009)
Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infectionCell Host Microbe, 6
-
V Espinosa (2014)
Inflammatory monocytes orchestrate innate antifungal immunity in the lungPLoS Pathog, 10
-
B Amulic (2012)
Neutrophil function: from mechanisms to diseaseAnnu Rev Immunol, 30
-
M Bianchi (2011)
Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependentJ Allergy Clin Immunol, 127
-
SJ Park (2009)
Early NK cell-derived IFN-{gamma} is essential to host defense in neutropenic invasive aspergillosisJ Immunol, 182
-
O Gross (2009)
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defenceNature, 459
-
N Yapar (2014)
Epidemiology and risk factors for invasive candidiasisTher Clin Risk Manag, 10
-
AR Huppler (2014)
Role of neutrophils in IL-17-dependent immunity to mucosal candidiasisJ Immunol, 192
-
L Drago (2013)
Antimicrobial activity of pure platelet-rich plasma against microorganisms isolated from oral cavityBMC Microbiol, 13
-
MG Netea (2004)
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cellsJ Immunol, 172
-
MG Netea (2002)
The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasisJ Infect Dis, 185
-
C Biondo (2011)
Recognition of yeast nucleic acids triggers a host-protective type I interferon responseEur J Immunol, 41
-
S Bellocchio (2004)
The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivoJ Immunol, 172
-
J Yano (2012)
The acute neutrophil response mediated by S100 alarmins during vaginal Candida infections is independent of the Th17-pathwayPLoS One, 7
-
P Sudbery (2004)
The distinct morphogenic states of Candida albicansTrends Microbiol, 12
-
E Vermeulen (2013)
Azole resistance in Aspergillus fumigatus: a growing public health concernCurr Opin Infect Dis, 26
-
JR Linden (2013)
Galectin-3 plays an important role in protection against disseminated candidiasisMed Mycol, 51
-
JL Shaw (2013)
IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polypsAm J Respir Crit Care Med, 188
-
MM Mircescu (2009)
Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infectionJ Infect Dis, 200
-
H Sun (2013)
Dectin-2 is predominately macrophage restricted and exhibits conspicuous expression during Aspergillus fumigatus invasion in human lungCell Immunol, 284
-
I Kyrmizi (2013)
Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signalingJ Immunol, 191
-
AG Hise (2009)
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicansCell Host Microbe, 5
-
C Speth (2013)
Aspergillus fumigatus activates thrombocytes by secretion of soluble compoundsJ Infect Dis, 207
-
JL Werner (2011)
Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infectionInfect Immun, 79
-
HR Conti (2009)
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasisJ Exp Med, 206
-
PR Taylor (2014)
Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgammat and dectin-2Nat Immunol, 15
-
DC Ifrim (2014)
Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptorsClin Vaccine Immunol, 21
-
MS Lionakis (2013)
CX3CR1-dependent renal macrophage survival promotes Candida control and host survivalJ Clin Invest, 123
-
S Bruns (2010)
Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodAPLoS Pathog, 6
-
S Slesiona (2012)
Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophagesPLoS One, 7
-
FL Veerdonk (2009)
The macrophage mannose receptor induces IL-17 in response to Candida albicansCell Host Microbe, 5
-
F Botterel (2008)
Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitroBMC Microbiol, 8
-
A McCormick (2010)
NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatusMicrobes Infect, 12
-
A Gladiator (2013)
Cutting edge: IL-17-secreting innate lymphoid cells are essential for host defense against fungal infectionJ Immunol, 190
-
PY Bochud (2008)
Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantationN Engl J Med, 359
-
SP Smeekens (2014)
Autophagy is redundant for the host defense against systemic Candida albicans infectionsEur J Clin Microbiol Infect Dis, 33
-
MJ Grimm (2013)
Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in miceJ Immunol, 190
-
I Fidan (2014)
In vitro effects of Candida albicans and Aspergillus fumigatus on dendritic cells and the role of beta glucan in this effectAdv Clin Exp Med, 23
-
S Saevarsdottir (2004)
The potential role of mannan-binding lectin in the clearance of self-components including immune complexesScand J Immunol, 60
-
A Nahum (2011)
The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunityJ Allergy Clin Immunol, 127
-
DC Ifrim (2014)
Role of Dectin-2 for host defense against systemic infection with Candida glabrataInfect Immun, 82
-
HS Goodridge (2011)
Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'Nature, 472
-
R Menegazzi (2012)
Killing by neutrophil extracellular traps: fact or folklore?Blood, 119
-
ZG Ramirez-Ortiz (2011)
A nonredundant role for plasmacytoid dendritic cells in host defense against the human fungal pathogen Aspergillus fumigatusCell Host Microbe, 9
-
LY Chai (2010)
Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunityImmunology, 130
-
LL Zhu (2013)
C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infectionImmunity, 39
-
KA Zarember (2007)
Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletionJ Immunol, 178
-
LA Albacker (2013)
Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivityNat Med, 19
-
J Quintin (2014)
Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised miceEur J Immunol, 44
-
A Luca (2014)
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humansProc Natl Acad Sci U S A, 111
-
JB Mear (2014)
Candida albicans airway exposure primes the lung innate immune response against Pseudomonas aeruginosa infection through innate lymphoid cell recruitment and interleukin-22-associated mucosal responseInfect Immun, 82
-
FL Veerdonk (2011)
STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasisN Engl J Med, 365
-
M Bouzani (2011)
Human NK cells display important antifungal activity against Aspergillus fumigatus, which is directly mediated by IFN-gamma releaseJ Immunol, 187
-
AM Nicola (2012)
Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicansInfect Immun, 80
-
MS Gresnigt (2013)
Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3J Immunol, 190
-
N Said-Sadier (2010)
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinasePLoS One, 5
-
SP Smeekens (2013)
Genetic susceptibility to Candida infectionsEMBO Mol Med, 5
-
D Serrano-Gomez (2004)
Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin mediates binding and internalization of Aspergillus fumigatus conidia by dendritic cells and macrophagesJ Immunol, 173
-
J Voigt (2014)
Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activityJ Infect Dis, 209
-
P Bonifazi (2010)
Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosisMucosal Immunol, 3
-
RP Gazendam (2014)
Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defectsBlood, 124
-
DL Moyes (2010)
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cellsCell Host Microbe, 8
-
JA Reales-Calderon (2014)
Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicansProteomics, 14
-
V Balloy (2005)
Involvement of toll-like receptor 2 in experimental invasive pulmonary aspergillosisInfect Immun, 73
-
A Carvalho (2012)
TLR3 essentially promotes protective class I-restricted memory CD8(+) T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patientsBlood, 119
-
S Schmidt (2011)
Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidiaJ Infect Dis, 203
-
MJ Robinson (2009)
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infectionJ Exp Med, 206
-
M Fei (2011)
TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infectionProc Natl Acad Sci U S A, 108
-
MG Netea (2008)
An integrated model of the recognition of Candida albicans by the innate immune systemNat Rev Microbiol, 6
-
S Saijo (2010)
Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicansImmunity, 32
-
Y Minegishi (2007)
Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndromeNature, 448
-
CA Wells (2008)
The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicansJ Immunol, 180
-
EK Rodland (2010)
Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of aspergillosisInfect Immun, 78
-
LM Lilly (2012)
The beta-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22J Immunol, 189
-
J Wagener (2014)
Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activationPLoS Pathog, 10
-
R Robert (2000)
Adherence of platelets to Candida species in vivoInfect Immun, 68
-
J Quintin (2012)
Candida albicans infection affords protection against reinfection via functional reprogramming of monocytesCell Host Microbe, 12
-
DM LeBlanc (2006)
Role for dendritic cells in immunoregulation during experimental vaginal candidiasisInfect Immun, 74
-
C Bourgeois (2011)
Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-beta signalingJ Immunol, 186
-
C Cunha (2013)
Human genetic susceptibility to invasive aspergillosisPLoS Pathog, 9
-
CF Urban (2009)
Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicansPLoS Pathog, 5
-
T Jouault (2006)
Specific recognition of Candida albicans by macrophages requires galectin-3 to discriminate Saccharomyces cerevisiae and needs association with TLR2 for signalingJ Immunol, 177
-
L McKinley (2008)
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in miceJ Immunol, 181
-
C Fresno (2013)
Interferon-beta production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicansImmunity, 38
-
A Cambi (2008)
Dendritic cell interaction with Candida albicans critically depends on N-linked mannanJ Biol Chem, 283
-
GD Brown (2002)
Dectin-1 is a major beta-glucan receptor on macrophagesJ Exp Med, 196
- Publisher
- Springer Journals
- Copyright
- Copyright © 2014 by Springer-Verlag Berlin Heidelberg
- Subject
- Biomedicine; Immunology; Internal Medicine
- ISSN
- 1863-2297
- eISSN
- 1863-2300
- DOI
- 10.1007/s00281-014-0467-z
- pmid
- 25527294
- Publisher site
- See Article on Publisher Site
Abstract
A large variety of fungi are present in the environment, among which a proportion colonizes the human body, usually without causing any harm. However, depending on the host immune status, commensals can become opportunistic pathogens that induce diseases ranging from superficial non-harmful infection to life-threatening systemic disease. The interplay between the host and the fungal commensal flora is being orchestrated by an efficient recognition of the microorganisms, which in turn ensures a proper balance between tolerance of the normal fungal flora and induction of immune defense mechanisms when invasion occurs. Pattern recognition receptors (PRRs) play a significant role in maintaining this balance due to their capacity to sense fungi and induce host responses such as the induction of proinflammatory cytokines involved in the activation of innate and adaptive immune responses. In the present review, we will discuss the most recent findings regarding the recognition of Candida albicans and Aspergillus fumigatus and the different types of immune cells that play a role in antifungal host defense.
Journal
Seminars in Immunopathology – Springer Journals
Published: Dec 20, 2014