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Table of Contents PIGMENT CELL & MELANOMA Volume 29 Research Number 6 November 2016 The official journal of the International Federation of Pigment Cell Societies and the Society for Melanoma Research Editorial Randy Lomax, 1947–2016 605 M. Herlyn Reviews The impact of skin colour on human photobiological responses 607 D. Fajuyigbe and A. R. Young The emerging role of long non-coding RNAs in cutaneous melanoma 619 E. Leucci, E. A. Coe, J.- C. Marine and K. W. Vance Melanoma central nervous system metastases: current approaches, challenges, and opportunities 627 J. V. Cohen, H. Tawbi, K. A. Margolin, R. Amravadi, M. Bosenberg, P. K. Brastianos, V. L. Chiang, J. de Groot, I. C. Glitza, M. Herlyn, S. L. Holmen, L. B. Jilaveanu, A. Lassman, S. Moschos, M. A. Postow, R. Thomas, J. A. Tsiouris, P. Wen, R. M. White, T. Turnham, M. A. Davies and H. M. Kluger Original Articles Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma * 643 B.- R. Wei, H. T. Michael, C. H.C. Halsey, C. J. Peer, A. Adhikari, J. E. Dwyer, S. B. Hoover, R. El Meskini, S. Kozlov, Z. Weaver Ohler, W. D. Figg, G. Merlino and R. M. Simpson Bidirectional cross talk between patient-derived melanoma and cancer-associated fibroblasts promotes invasion and proliferation * 656 B. Izar, C. E. Joyce, S. Goff, N. L. Cho, P. M. Shah, G. Sharma, J. Li, N. Ibrahim, J. Gold, F. S. Hodi, L. A. Garraway, C. D. Novina, M. M. Bertagnolli and C. H. Yoon Aerobic photoreactivity of synthetic eumelanins and pheomelanins: generation of singlet oxygen and superoxide anion * 669 G. Szewczyk, A. Zadlo, M. Sarna, S. Ito, K. Wakamatsu and T. Sarna Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors 679 M. Guida, S. Strippoli, A. Ferretta, N. Bartolomeo, L. Porcelli, I. Maida, A. Azzariti, S. Tommasi, C. Grieco, S. Guida, A. Albano, V. Lorusso and G. Guida Two light-activated neuroendocrine circuits arising in the eye trigger physiological and morphological pigmentation * 688 G. E. Bertolesi, C. L. Hehr, H. Munn and S. Mcfarlane Short Communication NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky–Pudlak syndrome patients * 702 A. Wei, Y. Yuan, D. Bai, J. Ma, Z. Hao, Y. Zhang, J. Yu, Z. Zhou, L. Yang, X. Yang, L. Li and W. Li Resource and Technologies Fluorescent quantification of melanin * 707 B. Fernandes, T. Matamá, D. Guimarães, A. Gomes and A. Cavaco-Paulo List of Reviewers List of reviewers for Volume 29 713 Meeting Abstracts Abstracts of the 20th Annual Meeting of the PanAmerican Society for Pigment Cell Research, Baltimore, Maryland, USA, October 5-8, 2016 E 1 Espcr 2015 E 19 * This paper contains supporting information, published on the web, see ‘Supporting Information’ section in the paper. Cover legend: Immune checkpoint inhibitors are currently achieving impressive results in clinical trials for melanoma. Yet mechanisms of resistance are beginning to emerge. The T-cell hammer represents current effective immunotherapy directed against differentiated melanomas (Blackberry) expressing neo-antigens. The potential for resistance is represented by the de-differentiated raspberry. Picture courtesy of Colin Goding. All Reviews are freely available online. Visit wileyonlinelibrary.com to search all articles and register for table of contents e-mail alerts. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pigment Cell & Melanoma Research Wiley

Table of Contents

Pigment Cell & Melanoma Research , Volume 29 (6) – Nov 1, 2016
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Publisher
Wiley
Copyright
Copyright © 2016 John Wiley & Sons A/S
ISSN
1755-1471
eISSN
1755-148X
DOI
10.1111/pcmr.12553
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Abstract

PIGMENT CELL & MELANOMA Volume 29 Research Number 6 November 2016 The official journal of the International Federation of Pigment Cell Societies and the Society for Melanoma Research Editorial Randy Lomax, 1947–2016 605 M. Herlyn Reviews The impact of skin colour on human photobiological responses 607 D. Fajuyigbe and A. R. Young The emerging role of long non-coding RNAs in cutaneous melanoma 619 E. Leucci, E. A. Coe, J.- C. Marine and K. W. Vance Melanoma central nervous system metastases: current approaches, challenges, and opportunities 627 J. V. Cohen, H. Tawbi, K. A. Margolin, R. Amravadi, M. Bosenberg, P. K. Brastianos, V. L. Chiang, J. de Groot, I. C. Glitza, M. Herlyn, S. L. Holmen, L. B. Jilaveanu, A. Lassman, S. Moschos, M. A. Postow, R. Thomas, J. A. Tsiouris, P. Wen, R. M. White, T. Turnham, M. A. Davies and H. M. Kluger Original Articles Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma * 643 B.- R. Wei, H. T. Michael, C. H.C. Halsey, C. J. Peer, A. Adhikari, J. E. Dwyer, S. B. Hoover, R. El Meskini, S. Kozlov, Z. Weaver Ohler, W. D. Figg, G. Merlino and R. M. Simpson Bidirectional cross talk between patient-derived melanoma and cancer-associated fibroblasts promotes invasion and proliferation * 656 B. Izar, C. E. Joyce, S. Goff, N. L. Cho, P. M. Shah, G. Sharma, J. Li, N. Ibrahim, J. Gold, F. S. Hodi, L. A. Garraway, C. D. Novina, M. M. Bertagnolli and C. H. Yoon Aerobic photoreactivity of synthetic eumelanins and pheomelanins: generation of singlet oxygen and superoxide anion * 669 G. Szewczyk, A. Zadlo, M. Sarna, S. Ito, K. Wakamatsu and T. Sarna Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors 679 M. Guida, S. Strippoli, A. Ferretta, N. Bartolomeo, L. Porcelli, I. Maida, A. Azzariti, S. Tommasi, C. Grieco, S. Guida, A. Albano, V. Lorusso and G. Guida Two light-activated neuroendocrine circuits arising in the eye trigger physiological and morphological pigmentation * 688 G. E. Bertolesi, C. L. Hehr, H. Munn and S. Mcfarlane Short Communication NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky–Pudlak syndrome patients * 702 A. Wei, Y. Yuan, D. Bai, J. Ma, Z. Hao, Y. Zhang, J. Yu, Z. Zhou, L. Yang, X. Yang, L. Li and W. Li Resource and Technologies Fluorescent quantification of melanin * 707 B. Fernandes, T. Matamá, D. Guimarães, A. Gomes and A. Cavaco-Paulo List of Reviewers List of reviewers for Volume 29 713 Meeting Abstracts Abstracts of the 20th Annual Meeting of the PanAmerican Society for Pigment Cell Research, Baltimore, Maryland, USA, October 5-8, 2016 E 1 Espcr 2015 E 19 * This paper contains supporting information, published on the web, see ‘Supporting Information’ section in the paper. Cover legend: Immune checkpoint inhibitors are currently achieving impressive results in clinical trials for melanoma. Yet mechanisms of resistance are beginning to emerge. The T-cell hammer represents current effective immunotherapy directed against differentiated melanomas (Blackberry) expressing neo-antigens. The potential for resistance is represented by the de-differentiated raspberry. Picture courtesy of Colin Goding. All Reviews are freely available online. Visit wileyonlinelibrary.com to search all articles and register for table of contents e-mail alerts.

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Pigment Cell & Melanoma Research – Wiley

Published: Nov 1, 2016

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