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Subcorneal pustular dermatosis followed by pyoderma gangrenosum

Subcorneal pustular dermatosis followed by pyoderma gangrenosum British Journal of Dermatology (1986) 115, 117-118. Correspondence Subcnrneal pustular dertnatosis followed by pyoderma gangrenosutn MADAM, We were interested 10 read the recent case report by Marsden and Millard (Brhish Journal of Dermatology 1986, 114, 125) of pyoderma gangrcnosum, subcomeal pustular dermatosis and IgA paraproteinaemia. We have recently seen a remarkably similar patieni. In 1979, a 59-ycar-oId woman presented with a 6-month history of a widespread burning eruption. Examination revealed i cm flaccid, pus-filled blisters (Fig. ia) and multiple superficial erosions, measuring 1-5 cm in diameter (Fig. ib). Some of these erosions were crusted, while others showed central clearing with a scaling serpiginous border, surrounded by a halo of erythema. Both bullac and erosions were widely scattered but showed a predilection for the flexural areas, including the groin, axillae and submammary region; the face was spared. Healing occurred slowly without scarring but left very persistent pigmented marks. Investigations showed a slight neutropenia(WBC: 3 7 x io^/!;44"o polymorphs)andanESRof55 mm/ hour, but were otherwise normal. Immunoglobutins were not measured. Biopsies of the lesions showed superficial pustules covered by a thin layer of keratin with occasional acantholytic cells. Polymorph neutrophils were seen infiltrating both the dermis and epidermis, singly and in groups. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png British Journal of Dermatology Oxford University Press

Subcorneal pustular dermatosis followed by pyoderma gangrenosum

Venning, V.A.; Ryan, T.J.
British Journal of Dermatology , Volume 115 (1): 2 – Jul 1, 1986
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References (1)

Publisher
Oxford University Press
Copyright
© 1986 British Association of Dermatologists
ISSN
0007-0963
eISSN
1365-2133
DOI
10.1111/j.1365-2133.1986.tb06229.x
Publisher site
See Article on Publisher Site

Abstract

British Journal of Dermatology (1986) 115, 117-118. Correspondence Subcnrneal pustular dertnatosis followed by pyoderma gangrenosutn MADAM, We were interested 10 read the recent case report by Marsden and Millard (Brhish Journal of Dermatology 1986, 114, 125) of pyoderma gangrcnosum, subcomeal pustular dermatosis and IgA paraproteinaemia. We have recently seen a remarkably similar patieni. In 1979, a 59-ycar-oId woman presented with a 6-month history of a widespread burning eruption. Examination revealed i cm flaccid, pus-filled blisters (Fig. ia) and multiple superficial erosions, measuring 1-5 cm in diameter (Fig. ib). Some of these erosions were crusted, while others showed central clearing with a scaling serpiginous border, surrounded by a halo of erythema. Both bullac and erosions were widely scattered but showed a predilection for the flexural areas, including the groin, axillae and submammary region; the face was spared. Healing occurred slowly without scarring but left very persistent pigmented marks. Investigations showed a slight neutropenia(WBC: 3 7 x io^/!;44"o polymorphs)andanESRof55 mm/ hour, but were otherwise normal. Immunoglobutins were not measured. Biopsies of the lesions showed superficial pustules covered by a thin layer of keratin with occasional acantholytic cells. Polymorph neutrophils were seen infiltrating both the dermis and epidermis, singly and in groups.

Journal

British Journal of Dermatology – Oxford University Press

Published: Jul 1, 1986

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