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Acquisition, analysis, or interpretation of data
- Publisher
- American Medical Association
- Copyright
- Copyright 2018 American Medical Association. All Rights Reserved.
- ISSN
- 2374-2437
- eISSN
- 2374-2445
- DOI
- 10.1001/jamaoncol.2017.4510
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionWhat are the relative and absolute risks of breast anaplastic large-cell lymphoma (ALCL) in women with breast implants? FindingsIn this population-based, case-control study, we identified 32 patients with primary breast-ALCL with ipsilateral breast implants. Relative risk for breast-ALCL in women with breast implants was 421.8 and absolute cumulative risk was 29 per million at age 50 years and 82 per million at age 70 years. MeaningBreast implants were associated with an increased relative risk of breast-ALCL, although the absolute risk remains small; the results suggest a need for increased clinical awareness, comprehensive registration of implants and complications, and stimulation of alternative cosmetic/reconstructive procedures.
Journal
JAMA Oncology – American Medical Association
Published: Mar 4, 2018