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References (26)
-
Cull Sg, R. Miledi, Ian Parker (1981)
Single glutamate‐activated channels recorded from locust muscle fibres with perfused patch‐clamp electrodesThe Journal of Physiology, 321
-
J. Kehoe, A. Marty (1980)
Certain slow synaptic responses: their properties and possible underlying mechanisms.Annual review of biophysics and bioengineering, 9
-
D. Colquhoun, E. Neher, H. Reuter, C. Stevens (1981)
Inward current channels activated by intracellular Ca in cultured cardiac cellsNature, 294
-
O. Hamill, B. Sakmann (1981)
Multiple conductance states of single acetylcholine receptor channels in embryonic muscle cellsNature, 294
-
E. Neher, B. Sakmann (1976)
Single-channel currents recorded from membrane of denervated frog muscle fibresNature, 260
-
M. Klein, E. Kandel (1978)
Presynaptic modulation of voltage-dependent Ca2+ current: mechanism for behavioral sensitization in Aplysia californica.Proceedings of the National Academy of Sciences of the United States of America, 75 7
-
A. Veerman, M. Nunes (1980)
Circadian rhythmicity participates in the photoperiodic determination of diapause in spider mitesNature, 287
-
H. Hartzell (1981)
Mechanisms of slow postsynaptic potentialsNature, 291
-
D. Paupardin-Tritsch, P. Deterre, H. Gerschenfeld (1981)
Relationship between two voltage-dependent serotonin responses of molluscan neuronesBrain Research, 217
-
A. Marty (1981)
Ca-dependent K channels with large unitary conductance in chromaffin cell membranesNature, 291
-
V. Castellucci, E. Kandel, J. Schwartz, F. Wilson, A. Nairn, P. Greengard (1980)
Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.Proceedings of the National Academy of Sciences of the United States of America, 77 12
-
J. Patlak, K. Gration, P. Usherwood (1979)
Single glutamate-activated channels in locust muscleNature, 278
-
M. Klein, E. Kandel (1980)
Mechanism of calcium current modulation underlying presynaptic facilitation and behavioral sensitization in Aplysia.Proceedings of the National Academy of Sciences of the United States of America, 77 11
-
F. Conti, E. Neher (1980)
Single channel recordings of K+ currents in squid axonsNature, 285
-
D. Adams, S. Smith, S. Thompson (1980)
Ionic currents in molluscan soma.Annual review of neuroscience, 3
-
R. Horn, J. Patlak, C. Stevens (1981)
Sodium channels need not open before they inactivateNature, 291
-
M. Brunelli, V. Castellucci, E. Kandel (1976)
Synaptic facilitation and behavioral sensitization in Aplysia: possible role of serotonin and cyclic AMP.Science, 194 4270
-
G. Yellen (1982)
Single Ca2+-activated nonselective cation channels in neuroblastomaNature, 296
-
M. Klein, E. Shapiro, E. Kandel (1980)
Synaptic plasticity and the modulation of the Ca2+ current.The Journal of experimental biology, 89
-
Harald Reuter, Charles Stevens, R. Tsien, Gary Yellen (1982)
Properties of single calcium channels in cardiac cell cultureNature, 297
-
T. Pellmar, D. Carpenter (1979)
Voltage-dependent calcium current induced by serotoninNature, 277
-
B. Jacobs, A. Gelperin (1981)
Serotonin neurotransmission and behavior -
C. Anderson, C. Stevens (1973)
Voltage clamp analysis of acetylcholine produced end‐plate current fluctuations at frog neuromuscular junctionThe Journal of Physiology, 235
-
BY Hodgkin, B. Katz (1949)
The effect of sodium ions on the electrical activity of the giant axon of the squidThe Journal of Physiology, 108
-
David Colquhoun, Bert Sakmann (1981)
Fluctuations in the microsecond time range of the current through single acetylcholine receptor ion channelsNature, 294
-
B. Pallotta, K. Magleby, J. Barrett (1981)
Single channel recordings of Ca2+-activated K+ currents in rat muscle cell cultureNature, 293
- Publisher
- Springer Journals
- Copyright
- Copyright © 1982 by Nature Publishing Group
- Subject
- Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
- ISSN
- 0028-0836
- eISSN
- 1476-4687
- DOI
- 10.1038/299413a0
- Publisher site
- See Article on Publisher Site
Abstract
We have identified a serotonin-sensitive K+ channel with novel properties. The channel is active at the resting potential; its gating is moderately affected by membrane potential and is not dependent on the activity of intracellular calcium ions. Application of serotonin to the cell body or intracellular injection of cyclic AMP causes prolonged and complete closure of the channel, thereby reducing the effective number of active channels in the membrane. The closure of the channel can account for the increases in the duration of the action potential, Ca2+ influx, and transmitter release which underlie behavioural sensitization, a simple form of learning.
Journal
Nature – Springer Journals
Published: Sep 30, 1982