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Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease.

Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease. The aim of the present study was to demonstrate the degeneration of the dopaminergic nigrostriatal pathway in Parkinson's disease by using the cocaine derivative [123I]beta-CIT (2-beta-carbomethoxy-3-beta(4-iodophenyl)-tropane or RTI-55) and SPECT and to relate the findings to the severity of the disease (Hoehn and Yahr scale, H/Y) and to clinical data such as motor score and activities of daily living. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of nuclear medicine : official publication, Society of Nuclear Medicine Pubmed

Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease.

Asenbaum, S; Brücke, T; Pirker, W; Podreka, I; Angelberger, P; Wenger, S; Wöber, C; Müller, C; Deecke, L
Journal of nuclear medicine : official publication, Society of Nuclear Medicine , Volume 38 (1): 6 – Feb 11, 1997
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Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease.


Abstract

The aim of the present study was to demonstrate the degeneration of the dopaminergic nigrostriatal pathway in Parkinson's disease by using the cocaine derivative [123I]beta-CIT (2-beta-carbomethoxy-3-beta(4-iodophenyl)-tropane or RTI-55) and SPECT and to relate the findings to the severity of the disease (Hoehn and Yahr scale, H/Y) and to clinical data such as motor score and activities of daily living.

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ISSN
0161-5505
pmid
8998140

Abstract

The aim of the present study was to demonstrate the degeneration of the dopaminergic nigrostriatal pathway in Parkinson's disease by using the cocaine derivative [123I]beta-CIT (2-beta-carbomethoxy-3-beta(4-iodophenyl)-tropane or RTI-55) and SPECT and to relate the findings to the severity of the disease (Hoehn and Yahr scale, H/Y) and to clinical data such as motor score and activities of daily living.

Journal

Journal of nuclear medicine : official publication, Society of Nuclear Medicine – Pubmed

Published: Feb 11, 1997

There are no references for this article.