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Clinical Pharmacokinetics of Anticonvulsants

Clinical Pharmacokinetics of Anticonvulsants Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies. The most important advantage is that the frequent interindividual variation in the plasma level/dose ratio for these drugs can be circumvented by plasma level monitoring. For several anticonvulsants the brain concentration is shown to parallel the plasma concentration. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Pharmacokinetics Springer Journals

Clinical Pharmacokinetics of Anticonvulsants

Hvidberg, Eigill; Dam, M.
Clinical Pharmacokinetics , Volume 1 (3) – Dec 15, 2012
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Publisher
Springer Journals
Copyright
Copyright
Subject
Medicine & Public Health; Pharmacotherapy; Pharmacology/Toxicology; Internal Medicine
ISSN
0312-5963
eISSN
1179-1926
DOI
10.2165/00003088-197601030-00001
Publisher site
See Article on Publisher Site

Abstract

Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies. The most important advantage is that the frequent interindividual variation in the plasma level/dose ratio for these drugs can be circumvented by plasma level monitoring. For several anticonvulsants the brain concentration is shown to parallel the plasma concentration.

Journal

Clinical Pharmacokinetics – Springer Journals

Published: Dec 15, 2012

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