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S. Hellewell, A. Bruce, G. Feinstein, J. Orringer, W. Williams, W. Bowen (1994)
Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labelingEuropean Journal of Pharmacology, 268
K. Heekeren, A. Neukirch, J. Daumann, M. Stoll, M. Obradovic, K. Kovar, M. Geyer, E. Gouzoulis-Mayfrank (2007)
Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosisJournal of Psychopharmacology, 21
A. Urani, P. Romieu, F. Roman, T. Maurice (2002)
Enhanced antidepressant effect of sigma1 (σ1) receptor agonists in β25–35-amyloid peptide-treated miceBehavioural Brain Research, 134
J. Saavedra, J. Axelrod (1972)
Psychotomimetic N-Methylated Tryptamines: Formation in Brain in vivo and in vitroScience, 175
D. Fontanilla, Molly Johannessen, A. Hajipour, N. Cozzi, M. Jackson, A. Ruoho (2009)
The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor RegulatorScience, 323
Teruo Hayashi, T. Su (2007)
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell SurvivalCell, 131
T. Collier, R. Waterhouse, M. Kassiou (2007)
Imaging sigma receptors: applications in drug development.Current pharmaceutical design, 13 1
T. Su (1982)
Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain.The Journal of pharmacology and experimental therapeutics, 223 2
Vladimir Vladimirov, B. Maher, B. Wormley, F. O’Neill, D. Walsh, K. Kendler, B. Riley (2009)
The trace amine associated receptor (TAAR6) gene is not associated with schizophrenia in the Irish Case-Control Study of Schizophrenia (ICCSS) sampleSchizophrenia Research, 107
S. Hellewell, A. Bruce, G. Feinstein, J. Orringer, W. Williams, W. Bowen (1994)
Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.European journal of pharmacology, 268 1
Marzia Martina, Marie‐Eve Turcotte, Samantha Halman, R. Bergeron (2007)
The sigma‐1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampusThe Journal of Physiology, 578
This work was supported by the Intramural Research Program of the National Institute on Drug Abuse, NIH, Department of Health and Human Services of the United States
J. Axelrod (1961)
Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring CompoundsScience, 134
P. Jenner, C. Marsden, C. Thanki (1980)
BEHAVIOURAL CHANGES INDUCED BY N,N‐DIMETHYLTRYPTAMINE IN RODENTSBritish Journal of Pharmacology, 69
Francina Langa, X. Codony, V. Tovar, Alfonso Lavado, E. Giménez, P. Cozar, Marta Cantero, A. Dordal, E. Hernández, Raquel Pérez, Xavier Monroy, D. Zamanillo, X. Guitart, L. Montoliu (2003)
Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.The European journal of neuroscience, 18 8
J. Daumann, K. Heekeren, A. Neukirch, C. Thiel, W. Möller-Hartmann, E. Gouzoulis-Mayfrank (2008)
Pharmacological modulation of the neural basis underlying inhibition of return (IOR) in the human 5-HT2A agonist and NMDA antagonist model of psychosisPsychopharmacology, 200
R. Strassman, C. Qualls, E. Uhlenhuth, R. Kellner (1994)
Dose-response study of N,N-dimethyltryptamine in humans. II. Subjective effects and preliminary results of a new rating scale.Archives of general psychiatry, 51 2
E. Gouzoulis-Mayfrank, K. Heekeren, A. Neukirch, M. Stoll, C. Stock, M. Obradovic, K. Kovar (2005)
Psychological Effects of (S)-Ketamine and N,N-Dimethyltryptamine (DMT): A Double-Blind, Cross-Over Study in Healthy VolunteersPharmacopsychiatry, 38
Anna Deliganis, P. Pierce, S. Peroutka (1991)
Differential interactions of dimethyltryptamine (DMT) with 5-HT1A and 5-HT2 receptors.Biochemical pharmacology, 41 11
Zheng-xiang Cheng, Danmei Lan, Pei-Ying Wu, Yanhua Zhu, Yi Dong, Lan Ma, P. Zheng (2008)
Neurosteroid dehydroepiandrosterone sulphate inhibits persistent sodium currents in rat medial prefrontal cortex via activation of sigma-1 receptorsExperimental Neurology, 210
Solomon Snyder, B. Largent (1989)
Receptor mechanisms in antipsychotic drug action: focus on sigma receptors.The Journal of neuropsychiatry and clinical neurosciences, 1 1
D. Vaupel (1983)
Naltrexone fails to antagonize the sigma effects of PCP and SKF 10,047 in the dog.European journal of pharmacology, 92 3-4
J. Bennett, S. Snyder (1976)
Serotonin and lysergic acid diethylamide binding in rat brain membranes: relationship to postsynaptic serotonin receptors.Molecular pharmacology, 12 3
E. Aydar, C. Palmer, V. Klyachko, M. Jackson (2002)
The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel SubunitNeuron, 34
J. Cedarbaum (2004)
SurvivalAmyotrophic Lateral Sclerosis and Other Motor Neuron Disorders, 5
I. Szara, A. Sai-Halász, Z. Boszormenyi (1957)
[Dimethyltryptamine as a new psychotic agent].Acta physiologica Academiae Scientiarum Hungaricae, 11 Suppl
J. Riba, M. Valle, G. Urbano, M. Yritia, A. Morte, M. Barbanoj (2003)
Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and PharmacokineticsJournal of Pharmacology and Experimental Therapeutics, 306
Hongling Zhang, J. Cuevas (2002)
Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons.Journal of neurophysiology, 87 6
R. Premont, R. Gainetdinov, M. Caron (2001)
Following the trace of elusive aminesProceedings of the National Academy of Sciences of the United States of America, 98
Tsung-Ping Su, E. London, J. Jaffe (1988)
Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems.Science, 240 4849
C. Gambelunghe, K. Aroni, Riccardo Rossi, Luca Moretti, M. Bacci (2008)
Identification of N,N-dimethyltryptamine and beta-carbolines in psychotropic ayahuasca beverage.Biomedical chromatography : BMC, 22 10
Teruo Hayashi, T. Su (2003)
Intracellular Dynamics of σ-1 Receptors (σ1 Binding Sites) in NG108-15 CellsJournal of Pharmacology and Experimental Therapeutics, 306
T. Wolinsky, C. Swanson, K. Smith, H. Zhong, B. Borowsky, P. Seeman, T. Branchek, C. Gerald (2007)
The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophreniaGenes, 6
J. Riba, A. Rodríguez-Fornells, G. Urbano, A. Morte, R. Antonijoan, M. Montero, J. Callaway, M. Barbanoj (2000)
Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteersPsychopharmacology, 154
P. Jenner, C. Marsden, C. Thanki (1978)
Behavioural changes induced by N,N-dimethyltryptamine in rodents [proceedings].British journal of pharmacology, 63 2
T. Mavlyutov, A. Ruoho (2007)
Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cellsJournal of Molecular Signaling, 2
R. Strassman, C. Qualls (1994)
Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects.Archives of general psychiatry, 51 2
D. Vaupel (1983)
Naltrexone fails to antagonize the σ effects of PCP and SKF 10,047 in the dogEuropean Journal of Pharmacology, 92
Adrien Renaudo, Sébastien L'hoste, H. Guizouarn, F. Borgese, O. Soriani (2007)
Cancer Cell Cycle Modulated by a Functional Coupling between Sigma-1 Receptors and Cl– Channels*Journal of Biological Chemistry, 282
(2009)
When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor
K. Heekeren, J. Daumann, A. Neukirch, C. Stock, W. Kawohl, C. Norra, T. Waberski, E. Gouzoulis-Mayfrank (2008)
Mismatch negativity generation in the human 5HT2A agonist and NMDA antagonist model of psychosisPsychopharmacology, 199
A. Sai-Halász, G. Brunecker, S. Szára (1958)
[Dimethyltryptamine: a new psycho-active drug].Psychiatria et neurologia, 135 4-5
J. Bunzow, M. Sonders, S. Arttamangkul, L. Harrison, Ge Zhang, D. Quigley, T. Darland, K. Suchland, Shailaja Pasumamula, James Kennedy, Susan Olson, R. Magenis, S. Amara, D. Grandy (2001)
Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor.Molecular pharmacology, 60 6
D. Amann, N. Avidan, K. Kanyas, Y. Kohn, A. Hamdan, E. Ben‐Asher, F. Macciardi, J. Beckmann, D. Lancet, B. Lerer (2006)
The trace amine receptor 4 gene is not associated with schizophrenia in a sample linked to chromosome 6q23Molecular Psychiatry, 11
Yelenis Herrera, C. Katnik, Jael Rodriguez, A. Hall, A. Willing, K. Pennypacker, J. Cuevas (2008)
σ-1 Receptor Modulation of Acid-Sensing Ion Channel a (ASIC1a) and ASIC1a-Induced Ca2+ Influx in Rat Cortical NeuronsJournal of Pharmacology and Experimental Therapeutics, 327
Francina Langa, X. Codony, V. Tovar, Alfonso Lavado, E. Giménez, P. Cozar, Marta Cantero, A. Dordal, E. Hernández, Raquel Pérez, Xavier Monroy, D. Zamanillo, X. Guitart, L. Montoliu (2003)
Generation and phenotypic analysis of sigma receptor type I (σ1) knockout miceEuropean Journal of Neuroscience, 18
B. Borowsky, N. Adham, K. Jones, R. Raddatz, R. Artymyshyn, K. Ogozalek, M. Durkin, P. Lakhlani, J. Bonini, S. Pathirana, N. Boyle, Xiaosui Pu, E. Kouranova, H. Lichtblau, F. Ochoa, T. Branchek, C. Gerald (2001)
Trace amines: Identification of a family of mammalian G protein-coupled receptorsProceedings of the National Academy of Sciences of the United States of America, 98
D. Mckenna, G. Towers, F. Abbott (1984)
Monoamine oxidase inhibitors in South American hallucinogenic plants: tryptamine and beta-carboline constituents of ayahuasca.Journal of ethnopharmacology, 10 2
W. Martin, C. Eades, J. Thompson, R. Huppler, P. Gilbert (1976)
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.The Journal of pharmacology and experimental therapeutics, 197 3
Teruo Hayashi, R. Rizzuto, G. Hajnóczky, T. Su (2009)
MAM: more than just a housekeeper.Trends in cell biology, 19 2
J. Duan, Maria Martinez, A. Sanders, C. Hou, N. Saitou, T. Kitano, B. Mowry, R. Crowe, J. Silverman, D. Levinson, P. Gejman (2004)
Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.American journal of human genetics, 75 4
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Published: Mar 10, 2009
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