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Combined neuroanatomical techniques were used to examine the organization of the striatal projection to the substantia nigra in the rat. Both double anterograde axonal tracing methods (Phaseolus vulgaris leuco‐agglutinin (PHA‐L) and 3H‐amino acid tract tracing) and double fluorescent retrograde axonal transport tracing methods were used to examine the relationship among striatal neurons projecting to separate areas of the substantia nigra. Additionally, the distributions of retrogradely labeled striatonigral projection neurons were charted relative to the neurochemically distinct striatal “patch” compartment, identified by substance P‐or leuenkephalin‐like immunoreactivity, and the complementary “matrix” compartment, identified by somatostatin‐like immunoreactive fibers.
The Journal of Comparative Neurology – Wiley
Published: Oct 22, 1986
Keywords: ; ; ;
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