N. Armes, James Smith (1997)
The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds.Development, 124 19
M. Price, F. Cruzalegui, R. Treisman (1996)
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c‐fos transcription in response to UV light.The EMBO Journal, 15
C. Hill, J. Wynne, R. Treisman (1995)
The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRFCell, 81
Hiroshi Hanafusa, J. Ninomiya-Tsuji, Norihisa Masuyama, M. Nishita, J. Fujisawa, H. Shibuya, Kunihiro Matsumoto, E. Nishida (1999)
Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-β-induced Gene Expression*The Journal of Biological Chemistry, 274
E. Piek, C. Heldin, P. Dijke (1999)
Specificity, diversity, and regulation in TGF‐β superfamily signalingThe FASEB Journal, 13
S. Germain, M. Howell, Graeme Esslemont, C. Hill (2000)
Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif.Genes & development, 14 4
C. Pierreux, F. Nicolás, C. Hill (2000)
Transforming Growth Factor β-Independent Shuttling of Smad4 between the Cytoplasm and NucleusMolecular and Cellular Biology, 20
B. Dérijard, M. Hibi, I-Huan Wu, T. Barrett, Bing Su, T. Deng, M. Karin, R. Davis (1994)
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domainCell, 76
S. Oh, T. Seki, Kendrick Goss, T. Imamura, Y. Yi, P. Donahoe, Li Li, K. Miyazono, P. Dijke, Seong-Jin Kim, E. Li (2000)
Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis.Proceedings of the National Academy of Sciences of the United States of America, 97 6
R. Wieser, J. Wrana, J. Massagué (1995)
GS domain mutations that constitutively activate T beta R‐I, the downstream signaling component in the TGF‐beta receptor complex.The EMBO Journal, 14
V. Bardwell, R. Treisman (1994)
The POZ domain: a conserved protein-protein interaction motif.Genes & development, 8 14
A. Nebreda, A. Porras (2000)
p38 MAP kinases: beyond the stress response.Trends in biochemical sciences, 25 6
Mary Price, Alan Rogers, Richard Treisman (1995)
Comparative analysis of the ternary complex factors Elk‐1, SAP‐1a and SAP‐2 (ERP/NET).The EMBO Journal, 14
J. Massagué, Ye-Guang Chen (2000)
Controlling TGF-β signalingGenes & Development
(2000)
Transcriptional control by the TGF‐β/Smad signaling systemThe EMBO Journal, 19
R. Marais, J. Wynne, R. Treisman (1993)
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domainCell, 73
A. Nakao, T. Imamura, S. Souchelnytskyi, M. Kawabata, A. Ishisaki, E. Oeda, K. Tamaki, J. Hanai, C. Heldin, K. Miyazono, P. Dijke (1997)
TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4The EMBO Journal, 16
E. Cocolakis, S. Lemay, Suhad Ali, J. Lebrun (2001)
The p38 MAPK Pathway Is Required for Cell Growth Inhibition of Human Breast Cancer Cells in Response to Activin*The Journal of Biological Chemistry, 276
Cancer Research UK London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields
M. Favata, K. Horiuchi, E. Manos, A. Daulerio, Deborah Stradley, W. Feeser, D. Dyk, W. Pitts, R. Earl, F. Hobbs, R. Copeland, R. Magolda, P. Scherle, J. Trzăskos (1998)
Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase*The Journal of Biological Chemistry, 273
R. Blake, M. Broome, Xiangdong Liu, Jianming Wu, M. Gishizky, Li Sun, S. Courtneidge (2000)
SU6656, a Selective Src Family Kinase Inhibitor, Used To Probe Growth Factor SignalingMolecular and Cellular Biology, 20
Sandrine Faure, Michelle Lee, T. Keller, P. Dijke, M. Whitman (2000)
Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development.Development, 127 13
S. Dennler, S. Itoh, D. Vivien, P. Dijke, S. Huet, J. Gauthier (1998)
Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 geneThe EMBO Journal, 17
P. Dijke, H. Yamashita, H. Ichijo, P. Franzén, M. Laiho, K. Miyazono, C. Heldin (1994)
Characterization of type I receptors for transforming growth factor-beta and activin.Science, 264 5155
R. Davis (2000)
Signal Transduction by the JNK Group of MAP KinasesCell, 103
H. Jörnvall, A. Blokzijl, P. Dijke, C. Ibáñez (2001)
The Orphan Receptor Serine/Threonine Kinase ALK7 Signals Arrest of Proliferation and Morphological Differentiation in a Neuronal Cell Line*The Journal of Biological Chemistry, 276
G. Blobe, W. Schiemann, H. Lodish (2000)
Role of transforming growth factor beta in human disease.The New England journal of medicine, 342 18
A. Sotiropoulos, D. Gineitis, J. Copeland, R. Treisman (1999)
Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin DynamicsCell, 98
A. Roberts, M. Sporn (1993)
Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)Growth Factors Journal, 8
Eva Reissmann, Henrik Jörnvall, A. Blokzijl, Olov Andersson, Chenbei Chang, Gabriella Minchiotti, M. Persico, Carlos Ibáñez, A. Brivanlou (2001)
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development.Genes & development, 15 15
J. Raingeaud, A. Whitmarsh, T. Barrett, B. Dérijard, R. Davis (1996)
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathwayMolecular and Cellular Biology, 16
G. Blobe, William Schiemann, Harvey Lodish (2000)
Role of Transforming Growth Factor in Human DiseaseThe New England Journal of Medicine
(1996)
but do not cooperate to establish thresholds
L. Gouédard, Ye-Guang Chen, Laurie Thevenet, C. Racine, Sandrine Borie, Isabelle Lamarre, N. Josso, J. Massagué, N. Clemente (2000)
Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Müllerian hormone and its type II receptor.The Journal of biological chemistry, 275 36
S. Bogdan, C. Klämbt (2001)
Epidermal growth factor receptor signalingCurrent Biology, 11
J. Massagué, S. Blain, R. Lo (2000)
TGFβ Signaling in Growth Control, Cancer, and Heritable DisordersCell, 103
M. Whitman (1998)
Smads and early developmental signaling by the TGFbeta superfamily.Genes & development, 12 16
J. Callahan, J. Burgess, J. Fornwald, L. Gaster, J. Harling, F. Harrington, J. Heer, C. Kwon, R. Lehr, A. Mathur, B. Olson, J. Weinstock, N. Laping (2002)
Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).Journal of medicinal chemistry, 45 5
Sandrine Faure, Michelle Lee, T. Keller, P. Dijke, M. Whitman (2000)
Endogenous patterns of TGF b superfamily signaling during early Xenopus development
T. Mohun, N. Garrett, R. Treisman (1987)
Xenopus cytoskeletal actin and human c‐fos gene promoters share a conserved protein‐binding site.The EMBO Journal, 6
A. Khwaja, K. Lehmann, B. Marte, J. Downward (1998)
Phosphoinositide 3-Kinase Induces Scattering and Tubulogenesis in Epithelial Cells through a Novel Pathway*The Journal of Biological Chemistry, 273
L. Attisano, J. Wrana, E. Montalvo, J. Massagué (1996)
Activation of signalling by the activin receptor complexMolecular and Cellular Biology, 16
M. Macías-Silva, P. Hoodless, Shao-Jun Tang, M. Buchwald, J. Wrana (1998)
Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2*The Journal of Biological Chemistry, 273
C. Hill, R. Marais, S. John, J. Wynne, S. Dalton, R. Treisman (1993)
Functional analysis of a growth factor-responsive transcription factor complexCell, 73
N. Laping, E. Grygielko, A. Mathur, S. Butter, J. Bomberger, C. Tweed, W. Martin, J. Fornwald, R. Lehr, J. Harling, L. Gaster, J. Callahan, B. Olson, Gene Sciences, Medicinal Chemistry (2002)
Inhibition of Transforming Growth Factor (TGF)- 1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF- Type I Receptor Kinase Activity: SB-431542
D. Gineitis, R. Treisman (2001)
Differential Usage of Signal Transduction Pathways Defines Two Types of Serum Response Factor Target Gene*The Journal of Biological Chemistry, 276
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Published: Jul 1, 2002
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