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Drug‐induced Febrile Mucocutaneous Syndrome

Drug‐induced Febrile Mucocutaneous Syndrome Abstract. A retrospective investigation of 89 cases of the Stevens‐Johnson and/or Lyell's syndrome showed that 77 patients (87%) had been treated with drugs, 2/3 of them for symptoms of respiratory and/or urinary infections. The most frequent drugs were longterm sulfonamide preparations, penicillins, butazones and antiepileptics. Mycoplasma pneumoniae and Staphylococcus aureus were the most common infective agents of those reported. More than 40% of the patients were below 20 years of age. There were more women than men. The mortality was 1–2% for the Stevens‐Johnson syndrome and 4 of 11 patients for Lyell's syndrome. It must be pointed out that, in the individual patient, it can be difficult to determine the etiology, especially in cases with infections. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Internal Medicine Wiley

Drug‐induced Febrile Mucocutaneous Syndrome

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References (34)

Publisher
Wiley
Copyright
"Copyright © 1975 Wiley Subscription Services, Inc., A Wiley Company"
ISSN
0954-6820
eISSN
1365-2796
DOI
10.1111/j.0954-6820.1975.tb19532.x
Publisher site
See Article on Publisher Site

Abstract

Abstract. A retrospective investigation of 89 cases of the Stevens‐Johnson and/or Lyell's syndrome showed that 77 patients (87%) had been treated with drugs, 2/3 of them for symptoms of respiratory and/or urinary infections. The most frequent drugs were longterm sulfonamide preparations, penicillins, butazones and antiepileptics. Mycoplasma pneumoniae and Staphylococcus aureus were the most common infective agents of those reported. More than 40% of the patients were below 20 years of age. There were more women than men. The mortality was 1–2% for the Stevens‐Johnson syndrome and 4 of 11 patients for Lyell's syndrome. It must be pointed out that, in the individual patient, it can be difficult to determine the etiology, especially in cases with infections.

Journal

Journal of Internal Medicine – Wiley

Published: Dec 12, 1975

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