V. Mootha, C. Lindgren, K. Eriksson, A. Subramanian, S. Sihag, J. Lehár, P. Puigserver, E. Carlsson, M. Ridderstråle, E. Laurila, N. Houstis, M. Daly, N. Patterson, J. Mesirov, T. Golub, P. Tamayo, B. Spiegelman, E. Lander, J. Hirschhorn, D. Altshuler, L. Groop (2003)
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesNature Genetics, 34
L. Garraway, D. Lin, S. Signoretti, D. Waltregny, J. Dilks, N. Bhattacharya, M. Loda (2003)
Intermediate basal cells of the prostate: In vitro and in vivo characterizationThe Prostate, 55
M. Dickson, W. Hahn, Y. Ino, V. Ronfard, Jenny Wu, R. Weinberg, D. Louis, Frederick Li, J. Rheinwald (2000)
Human Keratinocytes That Express hTERT and Also Bypass a p16INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation CharacteristicsMolecular and Cellular Biology, 20
D. Bello, M. Webber, H. Kleinman, D. Wartinger, J. Rhim (1997)
Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18.Carcinogenesis, 18 6
Jing Yu, Anita Boyapati, K. Rundell (2001)
Critical role for SV40 small-t antigen in human cell transformation.Virology, 290 2
R. Berger, P. Febbo, P. Majumder, Jean Zhao, Shayan Mukherjee, S. Signoretti, K. Campbell, W. Sellers, T. Roberts, M. Loda, T. Golub, W. Hahn (2004)
Human Prostate Epithelial Cells Androgen-Induced Differentiation and Tumorigenicity of Updated
Meenakshi Jain, Constadina Arvanitis, K. Chu, W. Dewey, E. Leonhardt, M. Trinh, Christopher Sundberg, J. Bishop, D. Felsher (2002)
Sustained Loss of a Neoplastic Phenotype by Brief Inactivation of MYCScience, 297
Simon Hayward, Mark Rosen, G. Cunha (1997)
Stromal-epithelial interactions in the normal and neoplastic prostate.British journal of urology, 79 Suppl 2
P. Weijerman, J. König, Stephen Wong, Hubert Niesters, D. Peehl (1994)
Lipofection-mediated immortalization of human prostatic epithelial cells of normal and malignant origin using human papillomavirus type 18 DNA.Cancer research, 54 21
P. Roy-burman, Hong Wu, W. Powell, J. Hagenkord, M. Cohen (2004)
Genetically defined mouse models that mimic natural aspects of human prostate cancer development.Endocrine-related cancer, 11 2
(2003)
Reprints and Subscriptions Permissions
Cheng Li, W. Wong (2001)
Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection.Proceedings of the National Academy of Sciences of the United States of America, 98 1
K. Stone, D. Mickey, H. Wunderli, G. Mickey, D. Paulson (1978)
Isolation of a human prostate carcinoma cell line (DU 145)International Journal of Cancer, 21
A. Cristofano, M. Acetis, A. Koff, C. Cordon-Cardo, P. Pandolfi (2001)
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouseNature Genetics, 27
Y. Shang, M. Myers, Myles Brown (2002)
Formation of the androgen receptor transcription complex.Molecular cell, 9 3
Todd Golub, Todd Golub, D. Slonim, Pablo Tamayo, Christine Huard, Michelle Gaasenbeek, J. Mesirov, Hilary Coller, M. Loh, James Downing, Michael Caligiuri, C. Bloomfield, Eric Lander (1999)
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.Science, 286 5439
E. Crawford, M. Eisenberger, D. Mcleod, J. Spaulding, R. Benson, F. Dorr, B. Blumenstein, M. Davis, P. Goodman (1989)
A controlled trial of leuprolide with and without flutamide in prostatic carcinoma.The New England journal of medicine, 321 7
Dinesh Singh, P. Febbo, K. Ross, D. Jackson, J. Manola, C. Ladd, P. Tamayo, A. Renshaw, A. D'Amico, J. Richie, E. Lander, M. Loda, P. Kantoff, T. Golub, W. Sellers (2002)
Gene expression correlates of clinical prostate cancer behavior.Cancer cell, 1 2
Katharine Ellwood-Yen, T. Graeber, John Wongvipat, M. Iruela-Arispe, Jianfeng Zhang, Jianfeng Zhang, R. Matusik, G. Thomas, C. Sawyers (2003)
Myc-driven murine prostate cancer shares molecular features with human prostate tumors.Cancer cell, 4 3
S. Sweat, A. Pacelli, E. Bergstralh, J. Slezak, D. Bostwick (1999)
Androgen receptor expression in prostatic intraepithelial neoplasia and cancer.The Journal of urology, 161 4
J. Moul, P. Friedrichs, R. Lance, S. Theune, E. Chang (1992)
Infrequent RAS oncogene mutations in human prostate cancerThe Prostate, 20
N. Craft, Y. Shostak, M. Carey, C. Sawyers (1999)
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinaseNature Medicine, 5
M. Nakahara, Masayuki Fukushima, Takatoshi Tachyo, T. Usui, T. Ide (1990)
Establishment of a SV40-transformed cell line from primary culture of rat dorsolateral prostatic epithelial cells.Experimental cell research, 190 2
Sma Phillips, CM Barton, S. Lee, D. Morton, D. Wallace, N. Lemoine, J. Neoptolemos (1994)
Loss of the retinoblastoma susceptibility gene (RB1) is a frequent and early event in prostatic tumorigenesis.British Journal of Cancer, 70
D. Coffey, J. Isaacs (1981)
Control of prostate growth.Urology, 17 Suppl 3
G. Cunha, S. Hayward, Yuzhuo Wang, W. Ricke (2003)
Role of the stromal microenvironment in carcinogenesis of the prostateInternational Journal of Cancer, 107
Shunyou Wang, Jing Gao, Q. Lei, N. Rozengurt, C. Pritchard, J. Jiao, G. Thomas, Gang Li, P. Roy-burman, P. Nelson, Xin Liu, Hong Wu (2003)
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer.Cancer cell, 4 3
S. Balk (2002)
Androgen receptor as a target in androgen-independent prostate cancer.Urology, 60 3 Suppl 1
W. Hahn, C. Counter, A. Lundberg, R. Beijersbergen, M. Brooks, R. Weinberg (1999)
Creation of human tumour cells with defined genetic elementsNature, 400
K. Klein, R. Reiter, James Redula, H. Moradi, X. Zhu, A. Brothman, D. Lamb, M. Marcelli, A. Belldegrun, O. Witte, C. Sawyers (1997)
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID miceNature Medicine, 3
B. Elenbaas, L. Spirio, F. Koerner, M. Fleming, D. Zimonjic, Joana Donaher, N. Popescu, W. Hahn, R. Weinberg (2001)
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.Genes & development, 15 1
G. Cunha, S. Hayward, Yuzhuo Wang (2002)
Role of stroma in carcinogenesis of the prostate.Differentiation; research in biological diversity, 70 9-10
James Voeller, L. Sugars, T. Pretlow, E. Gelmann (1994)
p53 oncogene mutations in human prostate cancer specimens.The Journal of urology, 151 2
R. Bookstein, P. Rio, S. Madreperla, F. Hong, Craig ALLREDt, W. Grizzle, Wen-Hwa Lee (1990)
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.Proceedings of the National Academy of Sciences of the United States of America, 87
J. Killion, R. Radinsky, I. Fidler (1998)
Orthotopic Models are Necessary to Predict Therapy of Transplantable Tumors in MiceCancer and Metastasis Reviews, 17
A. Lundberg, S. Randell, S. Stewart, B. Elenbaas, Kimberly Hartwell, M. Brooks, M. Fleming, J. Olsen, Scott Miller, R. Weinberg, W. Hahn (2002)
Immortalization and transformation of primary human airway epithelial cells by gene transferOncogene, 21
K. MacKenzie, S. Franco, A. Naiyer, C. May, M. Sadelain, S. Rafii, M. Moore (2002)
Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-rasOncogene, 21
N. Navone, C. Logothetis, A. Eschenbach, P. Troncoso (1998)
Model Systems of Prostate Cancer: Uses and LimitationsCancer and Metastasis Reviews, 17
R. Henke, E. Krüger, N. Ayhan, D. Hübner, P. Hammerer, H. Huland (1994)
Immunohistochemical detection of p53 protein in human prostatic cancer.The Journal of urology, 152 4
J. Rich, Chuan-hai Guo, R. McLendon, D. Bigner, Xiao-Fan Wang, C. Counter (2001)
A genetically tractable model of human glioma formation.Cancer research, 61 9
P. Majumder, J. Yeh, D. George, P. Febbo, J. Kum, Q. Xue, Rachel Bikoff, Hon-Kwang Ma, P. Kantoff, T. Golub, M. Loda, W. Sellers (2003)
Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: The MPAKT modelProceedings of the National Academy of Sciences of the United States of America, 100
W. Huss, Lisette Maddison, N. Greenberg (2001)
Autochthonous mouse models for prostate cancer: past, present and future.Seminars in cancer biology, 11 3
P. Weijerman, H. Romijn, D. Peehl (1994)
Human papilloma virus type 18 DNA immortalized cell lines from the human prostate epithelium.Progress in clinical and biological research, 386
S. Hayward, Yuzhuo Wang, Mei Cao, Y. Hom, Baohui Zhang, G. Grossfeld, D. Sudilovsky, G. Cunha (2001)
Malignant transformation in a nontumorigenic human prostatic epithelial cell line.Cancer research, 61 22
N. Konishi, Y. Hiasa, T. Tsuzuki, Ming Tao, Takayuki Enomoto, G. Miller (1997)
Comparison of ras activation in prostate carcinoma in Japanese and American menThe Prostate, 30
P. Cairns, K. Okami, S. Halachmi, N. Halachmi, M. Esteller, J. Herman, J. Jen, W. Isaacs, G. Bova, D. Sidransky (1997)
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.Cancer research, 57 22
M. Kaighn, Narayanaswamy Ks, Y. Ohnuki, J. Lechner, L. Jones (1979)
Establishment and characterization of a human prostatic carcinoma cell line (PC-3).Investigative urology, 17 1
Jean Zhao, O. Gjoerup, R. Subramanian, Yuan Cheng, Wen Chen, T. Roberts, W. Hahn (2003)
Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase.Cancer cell, 3 5
D. Felsher, J. Bishop (1999)
Reversible tumorigenesis by MYC in hematopoietic lineages.Molecular cell, 4 2
C. Chen, D. Welsbie, C. Tran, S. Baek, Randolph Chen, R. Vessella, M. Rosenfeld, C. Sawyers (2004)
Molecular determinants of resistance to antiandrogen therapyNature Medicine, 10
(2004)
American Association for Cancer cancerres.aacrjournals.org Downloaded from
Robert Jenkins, J. Qian, M. Lieber, D. Bostwick (1997)
Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization.Cancer research, 57 3
P. Berthon, Andrew Waller, J. Villette, Ludovic Loridon, O. Cussenot, N. Maitland (1997)
Androgens are not a direct requirement for the proliferation of human prostatic epithelium in vitroInternational Journal of Cancer, 73
Cheng Li, Wing Wong (2001)
Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error applicationGenome Biology, 2
L. Chin, Alice Tam, J. Pomerantz, M. Wong, J. Holash, N. Bardeesy, Qiong Shen, R. O'Hagan, J. Pantginis, Hao Zhou, J. Horner, C. Cordon-Cardo, G. Yancopoulos, R. DePinho (1999)
Essential role for oncogenic Ras in tumour maintenanceNature, 400
S. Kasper, P. Sheppard, Y. Yan, N. Pettigrew, A. Borowsky, G. Prins, J. Dodd, M. Duckworth, R. Matusik (1998)
Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer.Laboratory investigation; a journal of technical methods and pathology, 78 6
S. Signoretti, S. Signoretti, D. Waltregny, J. Dilks, Beth Isaac, D. Lin, L. Garraway, A. Yang, Rondolfo Montironi, F. McKeon, M. Loda, M. Loda (2000)
p63 is a prostate basal cell marker and is required for prostate development.The American journal of pathology, 157 6
K. Anwar, K. Nakakuki, T. Shiraishi, H. Naiki, R. Yatani, Manabu Inzuka (1992)
Presence of ras oncogene mutations and human papillomavirus DNA in human prostate carcinomas.Cancer research, 52 21
Robert Bright, Robert Bright, C. Vocke, M. Emmert-Buck, Paul Duray, Diane Solomon, P. Fetsch, Johng Rhim, W. Linehan, S. Topalian (1997)
Generation and genetic characterization of immortal human prostate epithelial cell lines derived from primary cancer specimens.Cancer research, 57 5
Michael Stanbrough, I. Leav, P. Kwan, G. Bubley, S. Balk (2001)
Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epitheliumProceedings of the National Academy of Sciences of the United States of America, 98
I. Weinstein (2002)
Addiction to Oncogenes--the Achilles Heal of CancerScience, 297
T. Kiyono, S. Foster, Jenn Koop, J. McDougall, D. Galloway, A. Klingelhutz (1998)
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cellsNature, 396
C. Huettner, Pu Zhang, R. Etten, D. Tenen (2000)
Reversibility of acute B-cell leukaemia induced by BCR–ABL1Nature Genetics, 24
Cancer Research – Unpaywall
Published: Dec 15, 2004
Access the full text.
Sign up today, get DeepDyve free for 14 days.