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Progress and challenges in genome-wide association studies in humans

Progress and challenges in genome-wide association studies in humans After more than a decade of hope and hype, researchers are finally making inroads into understanding the genetic basis of many common human diseases. The use of genome-wide association studies has broken the logjam, enabling genetic variants at specific loci to be associated with particular diseases. Genetic association data are now providing new routes to understanding the aetiology of disease, as well as new footholds on the long and difficult path to better treatment and disease prevention. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Springer Journals

Progress and challenges in genome-wide association studies in humans

Nature , Volume 456 (7223) – Dec 10, 2008

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Publisher
Springer Journals
Copyright
Copyright © 2008 by Nature Publishing Group
Subject
Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
ISSN
0028-0836
eISSN
1476-4687
DOI
10.1038/nature07631
Publisher site
See Article on Publisher Site

Abstract

After more than a decade of hope and hype, researchers are finally making inroads into understanding the genetic basis of many common human diseases. The use of genome-wide association studies has broken the logjam, enabling genetic variants at specific loci to be associated with particular diseases. Genetic association data are now providing new routes to understanding the aetiology of disease, as well as new footholds on the long and difficult path to better treatment and disease prevention.

Journal

NatureSpringer Journals

Published: Dec 10, 2008

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