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Detection of ventricular thrombosis in acute myocardial infarction: Value of indium-111 platelet scintigraphy in relation to two-dimensional echocardiography and clinical course

Detection of ventricular thrombosis in acute myocardial infarction: Value of indium-111 platelet... In order to detect left ventricular (LV) thrombosis, 111In-platelet scintigraphy and two-dimensional echocardiography were performed in 40 patients 15 days±6 days after acute myocardial infarction. A dual isotope subtraction method, using 111In-platelet scintigraphy and 99mTc-blood pool scintigraphy, was used to assess LV platelet deposition expressed as LV counts per pixed. Seven patients (group A) had a positive 111In-platelet scintigram and 33 patients (group B) had a negative 111In-platelet scintigram (LV counts per pixel: 0.56±0.23 and 0.28±0.19, respectively, P<0.05). Three group A patients but no group B patients had a positive echocardiogram. Arterial embolism was noted in four patients, of whom two showed both positive echocardiogram and platelet scintigram. LV counts per pixel were 0.57±0.13 and 0.31±0.21, respectively (P<0.02) in patients with and without arterial embolism. Thus, both 111In-platelet scintigraphy and two-dimensional echocardiography can detect LV thrombosis. 111In-platelet scintigraphy may help to define patients at risk for embolization and may be used in conjunction with echocardiography to study the effect of antithrombotic therapy. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Nuclear Medicine and Molecular Imaging Springer Journals

Detection of ventricular thrombosis in acute myocardial infarction: Value of indium-111 platelet scintigraphy in relation to two-dimensional echocardiography and clinical course

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References (29)

Publisher
Springer Journals
Copyright
Copyright © 1986 by Springer-Verlag
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Orthopedics; Cardiology; Oncology
ISSN
1619-7070
eISSN
1619-7089
DOI
10.1007/BF00263815
Publisher site
See Article on Publisher Site

Abstract

In order to detect left ventricular (LV) thrombosis, 111In-platelet scintigraphy and two-dimensional echocardiography were performed in 40 patients 15 days±6 days after acute myocardial infarction. A dual isotope subtraction method, using 111In-platelet scintigraphy and 99mTc-blood pool scintigraphy, was used to assess LV platelet deposition expressed as LV counts per pixed. Seven patients (group A) had a positive 111In-platelet scintigram and 33 patients (group B) had a negative 111In-platelet scintigram (LV counts per pixel: 0.56±0.23 and 0.28±0.19, respectively, P<0.05). Three group A patients but no group B patients had a positive echocardiogram. Arterial embolism was noted in four patients, of whom two showed both positive echocardiogram and platelet scintigram. LV counts per pixel were 0.57±0.13 and 0.31±0.21, respectively (P<0.02) in patients with and without arterial embolism. Thus, both 111In-platelet scintigraphy and two-dimensional echocardiography can detect LV thrombosis. 111In-platelet scintigraphy may help to define patients at risk for embolization and may be used in conjunction with echocardiography to study the effect of antithrombotic therapy.

Journal

European Journal of Nuclear Medicine and Molecular Imaging – Springer Journals

Published: Aug 9, 2004

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