Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/springer-journals/simultaneous-blockade-of-5-ht-1a-b-receptors-and-5-ht-transporters-Ehskpc0IDa
References (69)
-
E. Rabiner, Z. Bhagwagar, R. Gunn, P. Sargent, Christopher Bench, P. Cowen, Paul Grasby (2001)
Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low.The American journal of psychiatry, 158 12
-
I. Malagié, A. Trillat, Christian Jacquot, A. Gardier (1995)
Effects of acute fluoxetine on extracellular serotonin levels in the raphe: an in vivo microdialysis study.European journal of pharmacology, 286 2
-
A. Gobert, J. Rivet, L. Cistarelli, M. Millan (1997)
Potentiation of the Fluoxetine‐Induced Increase in Dialysate Levels of Serotonin (5‐HT) in the Frontal Cortex of Freely Moving Rats by Combined Blockade of 5‐HT1A and 5‐HT1B Receptors with WAY 100,635 and GR 127,935Journal of Neurochemistry, 68
-
G. Shalom, E. Gur, L. Kar, M. Newman (2004)
Repeated administration of the 5-HT1B receptor antagonist SB-224289 blocks the desensitisation of 5-HT1B autoreceptors induced by fluoxetine in rat frontal cortexNaunyn-Schmiedeberg's Archives of Pharmacology, 370
-
L. Romero, N. Bel, F. Artigas, C. Montigny, P. Blier (1996)
Effect of Pindolol on the Function of Pre- and Postsynaptic 5-HT1A Receptors: In Vivo Microdialysis and Electrophysiological Studies in the Rat BrainNeuropsychopharmacology, 15
-
A. Gobert, A. Dekeyne, M. Millan (2000)
The ability of WAY100,635 to potentiate the neurochemical and functional actions of fluoxetine is enhanced by co-administration of SB224,289, but not BRL15572Neuropharmacology, 39
-
C. Roberts, P. Hatcher, J. Hagan, N. Austin, P. Jeffrey, P. Wyman, L. Gaster, C. Routledge, D. Middlemiss (2000)
The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pigNaunyn-Schmiedeberg's Archives of Pharmacology, 362
-
M. Hajós, S. Gartside, A. Villa, T. Sharp (1995)
Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the ratNeuroscience, 69
-
P. Atkinson, S. Bromidge, M. Duxon, L. Gaster, M. Hadley, B. Hammond, Christopher Johnson, D. Middlemiss, Stephanie North, G. Price, H. Rami, G. Riley, C. Scott, Tracy Shaw, K. Starr, G. Stemp, K. Thewlis, David Thomas, M. Thompson, A. Vong, J. Watson (2005)
3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity.Bioorganic & medicinal chemistry letters, 15 3
-
F Artigas, V Perez, E Alvarez (1994)
Pindolol induces a rapid improvement of patients with depression treated with serotonin reuptake inhibitorsArch Gen Psychiatry, 51
-
S. Gartside, V. Umbers, M. Hajós, T. Sharp (1995)
Interaction between a selective 5‐HT1A receptor antagonist and an SSRI in vivo: effects on 5‐HT cell firing and extracellular 5‐HTBritish Journal of Pharmacology, 115
-
B. Costall, A. Domeney, P. Gerrard, R. Naylor (2007)
A PRIMATE MODEL FOR THE ASSESSMENT OF ANXIOLYTIC DRUG ACTION -
L. Romero, F. Artigas (1997)
Preferential Potentiation of the Effects of Serotonin Uptake Inhibitors by 5‐HT1A Receptor Antagonists in the Dorsal Raphe Pathway: Role of Somatodendritic AutoreceptorsJournal of Neurochemistry, 68
-
R. Berman, A. Anand, A. Cappiello, H. Miller, X. Hu, D. Oren, D. Charney (1999)
The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trialBiological Psychiatry, 45
-
L. Dreshfield, D. Wong, K. Perry, E. Engleman (1996)
Enhancement of fluoxetine-dependent increase of extracellular serotonin (5-HT) levels by (−)-pindolol, an antagonist at 5-HT1A receptorsNeurochemical Research, 21
-
S. Hjorth, H. Bengtsson, A. Kullberg, D. Carlzon, H. Peilot, S. Auerbach (2000)
Serotonin autoreceptor function and antidepressant drug actionJournal of Psychopharmacology, 14
-
D. Thomas, D. Nelson, A. Johnson (2004)
Biochemical effects of the antidepressant paroxetine, a specific 5-hydroxytryptamine uptake inhibitorPsychopharmacology, 93
-
L. Dawson, H. Nguyen, D. Smith, L. Schechter (2000)
Effects of chronic fluoxetine treatment in the presence and absence of (±)pindolol: a microdialysis studyBritish Journal of Pharmacology, 130
-
É. Hajós‐Korcsok, S. McTavish, T. Sharp (2000)
Effect of a selective 5-hydroxytryptamine reuptake inhibitor on brain extracellular noradrenaline: microdialysis studies using paroxetine.European journal of pharmacology, 407 1-2
-
C. Rapisarda, B. Bacchelli (1977)
The brain of the guinea pig in stereotaxic coordinates.Archivio di scienze biologiche, 61 1-4
-
F. Artigas, V. Pérez, E. Álvarez (1994)
Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors.Archives of general psychiatry, 51 3
-
C. Beyer, S. Boikess, B. Luo, L. Dawson (2002)
Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis studyJournal of Psychopharmacology, 16
-
Stephan Hjorth (1996)
(-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine.European journal of pharmacology, 303 3
-
R Bordet, P Thomas, B Dupuis (1998)
Effect of pindolol on onset of action of paroxetine in the treatment of major depression-intermediate analysis of a double-blind, placebo-controlled trialAm J Psychiatry, 155
-
T. Stean, Alan Atkins, C. Heidbreder, L. Quinn, B. Trail, N. Upton (2005)
Postsynaptic 5‐HT1B receptors modulate electroshock‐induced generalised seizures in ratsBritish Journal of Pharmacology, 144
-
E. Poul, N. Laaris, É. Doucet, A. Laporte, M. Hamon, L. Lanfumey (1995)
Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetineNaunyn-Schmiedeberg's Archives of Pharmacology, 352
-
K. Starr, G. Price, J. Watson, P. Atkinson, R. Arban, S. Melotto, L. Dawson, J. Hagan, N. Upton, M. Duxon (2007)
SB-649915-B, a Novel 5-HT1A/B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction TestNeuropsychopharmacology, 32
-
M. Duxon, K. Starr, N. Upton (2000)
Latency to paroxetine‐induced anxiolysis in the rat is reduced by co‐administration of the 5‐HT1A receptor antagonist WAY100635British Journal of Pharmacology, 130
-
E. O'hearn, M. Molliver (1984)
Organization of raphe-cortical projections in rat: A quantitative retrograde studyBrain Research Bulletin, 13
-
J. Casanovas, I. Hervás, F. Artigas (1999)
Postsynaptic 5-HT1A receptors control 5-HT release in the rat medial prefrontal cortex.Neuroreport, 10 7
-
R. Berman, A. Darnell, H. Miller, A. Anand, D. Charney (1997)
Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial.The American journal of psychiatry, 154 1
-
G. Paxinos, Charles Watson (1983)
The Rat Brain in Stereotaxic Coordinates -
LA Dawson, HQ Nguyen (1998)
Effects of the 5-HT1A receptor antagonists on fluoxetine-induced changes in serotonin in rat frontal cortexEur J Pharmacol, 345
-
I. Hervás, M. Vilaró, L. Romero, M. Scorza, G. Mengod, F. Artigas (2001)
Desensitization of 5-HT1A Autoreceptors by a Low Chronic Fluoxetine Dose Effect of the Concurrent Administration of WAY-100635Neuropsychopharmacology, 24
-
S Hjorth, SB Auerbach (1996)
5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI)Behav Brain Res, 73
-
C. Roberts, G. Price, L. Gaster, B. Jones, D. Middlemiss, C. Routledge (1997)
Importance of h5-HT1B Receptor Selectivity for 5-HT Terminal Autoreceptor Activity: an In Vivo Microdialysis Study in the Freely-moving Guinea-pigNeuropharmacology, 36
-
P. Blier, C. Montigny, Y. Chaput (1987)
Modifications of the Serotonin System by Antidepressant Treatments: Implications for the Therapeutic Response in Major DepressionJournal of Clinical Psychopharmacology, 7
-
R. Bordet, P. Thomas, B. Dupuis (1998)
Effect of pindolol on onset of action of paroxetine in the treatment of major depression: intermediate analysis of a double-blind, placebo-controlled trial. Réseau de Recherche et d'Expérimentation Psychopharmacologique.The American journal of psychiatry, 155 10
-
T. Sharp, V. Umbers, S. Gartside (1997)
Effect of a selective 5‐HT reuptake inhibitor in combination with 5‐HT1A and 5‐HT1B receptor antagonists on extracellular 5‐HT in rat frontal cortex in vivoBritish Journal of Pharmacology, 121
-
Z. Bacq (1956)
[Chemical protection against ionizing radiations].Triangulo, 5
-
B. Olivier, H. Molewijk, J. Heyden, R. Oorschot, E. Ronken, J. Mos, K. Miczek (1998)
Ultrasonic vocalizations in rat pups: effects of serotonergic ligandsNeuroscience & Biobehavioral Reviews, 23
-
P. Delgado, D. Charney, L. Price, G. Aghajanian, H. Landis, G. Heninger (1990)
Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan.Archives of general psychiatry, 47 5
-
C. Gardner (1985)
Distress vocalization in rat pups. A simple screening method for anxiolytic drugs.Journal of pharmacological methods, 14 3
-
C. Roberts, D. Boyd, D. Middlemiss, C. Routledge (1999)
Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockadeNeuropharmacology, 38
-
M. Gobbi, D. Crespi, M. Foddi, C. Fracasso, L. Mancini, L. Parotti, T. Mennini (1997)
Effects of chronic treatment with fluoxetine and citalopram on 5-HT uptake, 5-HT1B autoreceptors, 5-HT3 and 5-HT4 receptors in ratsNaunyn-Schmiedeberg's Archives of Pharmacology, 356
-
E. Forster, I. Cliffe, D. Bill, G. Dover, Deborah Jones, Y. Reilly, A. Fletcher (1995)
A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635.European journal of pharmacology, 281 1
-
(2005)
Neurochemical characterisation of the novel 5-HT1A/B receptor / serotonin transporter antagonist SB-649915-B -
C. Scott, E. Soffin, Matthew Hill, P. Atkinson, C. Langmead, P. Wren, S. Faedo, Laurie Gordon, G. Price, S. Bromidge, Christopher Johnson, J. Hagan, J. Watson (2006)
SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.European journal of pharmacology, 536 1-2
-
A. Kimball, W. Burnett, D. Doherty (1957)
Chemical protection against ionizing radiation. I. Sampling methods for screening compounds in radiation protection studies with mice.Radiation research, 7 1
-
(1999)
Serotonergic antidepressants: current and future perspectives -
R. McAskill, S. Mir, D. Taylor (1998)
Pindolol augmentation of antidepressant therapyBritish Journal of Psychiatry, 173
-
C. Roberts, J. Watson, M. Burton;, G. Price, B. Jones (1996)
Functional characterization of the 5‐HT terminal autoreceptor in the guinea‐pig brain cortexBritish Journal of Pharmacology, 117
-
L. Dawson, H. Nguyen (2000)
The role of 5-HT1A and 5-HT1B/1D receptors on the modulation of acute fluoxetine-induced changes in extracellular 5-HT: the mechanism of action of (±)pindololNeuropharmacology, 39
-
L. Dawson, H. Nguyen (1998)
Effects of 5-HT1A receptor antagonists on fluoxetine-induced changes in extracellular serotonin concentrations in rat frontal cortex.European journal of pharmacology, 345 1
-
JMR Delgado, DS Charney, LH Price, GK Aghajanian, H Landis, GR Heninger (1990)
Serotonin function and the mechanism of antidepressant action: reversal of antidepressant-induced remission by rapid depletion of plasma tryptophanArch Gen Physchiatry, 47
-
S. Siehler, Klaus Seuwen, D. Hoyer (1999)
Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studiesNaunyn-Schmiedeberg's Archives of Pharmacology, 360
-
P. Blier, R. Bergeron (1995)
Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression.Journal of clinical psychopharmacology, 15 3
-
J. Litchfield, F. Wilcoxon (1948)
A simplified method of evaluating dose-effect experiments.The Journal of pharmacology and experimental therapeutics, 96 2
-
L. Romero, I. Hervás, F. Artigas (1996)
The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brainNeuroscience Letters, 219
-
L. Dawson, H. Nguyen, D. Smith, L. Schechter (2002)
Effect of chronic fluoxetine and WAY-100635 treatment on serotonergic neurotransmission in the frontal cortexJournal of Psychopharmacology, 16
-
M. Duxon, Jennifer Stretton, K. Starr, Declan Jones, Vicky Holland, G. Riley, J. Jerman, S. Brough, D. Smart, A. Johns, W. Chan, R. Porter, N. Upton (2000)
Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvementPsychopharmacology, 153
-
LJ Dreshfield, DT Wong, KW Perry, EA Engleman (1996)
Enhancement of fluoxetine-dependent serotonin (5-HT) levels by (-) pindolol, an antagonist at 5-HT1A receptorsNeurochem Res, 21
-
B. Kosofsky, M. Molliver (1987)
The serotoninergic innervation of cerebral cortex: Different classes of axon terminals arise from dorsal and median raphe nucleiSynapse, 1
-
E. Clifford, S. Gartside, V. Umbers, P. Cowen, M. Hajós, T. Sharp (1998)
Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5‐HT1A autoreceptor in vivoBritish Journal of Pharmacology, 124
-
S. Hogg, A. Dalvi (2004)
Acceleration of onset of action in schedule-induced polydipsia: combinations of SSRI and 5-HT1A and 5-HT1B receptor antagonistsPharmacology Biochemistry and Behavior, 77
-
S. Hjorth, D. Westlin, H. Bengtsson (1997)
Way100635-induced Augmentation of the 5-HT-elevating Action of Citalopram: Relative Importance of the Dose of the 5-HT1A (Auto)receptor Blocker Versus that of the 5-HT Reuptake InhibitorNeuropharmacology, 36
-
Y. Chaput, C. Montigny, P. Blier (1986)
Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: Electrophysiological studies in the rat brainNaunyn-Schmiedeberg's Archives of Pharmacology, 333
-
R. Zanardi, F. Artigas, L. Franchini, L. Sforzini, M. Gasperini, E. Smeraldi, Jorge Perez (1997)
How long should pindolol be associated with paroxetine to improve the antidepressant response?Journal of clinical psychopharmacology, 17 6
-
S. Hjorth, S. Auerbach (1995)
5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI)Behavioural Brain Research, 73
- Publisher
- Springer Journals
- Copyright
- Copyright © 2007 by Springer-Verlag
- Subject
- Biomedicine; Psychiatry ; Pharmacology/Toxicology
- ISSN
- 0033-3158
- eISSN
- 1432-2072
- DOI
- 10.1007/s00213-006-0691-x
- pmid
- 17265079
- Publisher site
- See Article on Publisher Site
Abstract
Based on these data, one may speculate that the 5-HT autoreceptor antagonist/5-HT transport inhibitor SB-649915-B will have therapeutic efficacy in the treatment of affective disorders with the potential for a faster onset of action compared to current selective serotonin reuptake inhibitors.
Journal
Psychopharmacology – Springer Journals
Published: May 1, 2007