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- Publisher
- Springer Journals
- Copyright
- Copyright © 1999 by Plenum Publishing Corporation
- Subject
- Biomedicine; Pharmacology/Toxicology; Pharmacy; Biochemistry, general; Medical Law; Biomedical Engineering
- ISSN
- 0724-8741
- eISSN
- 1573-904X
- DOI
- 10.1023/A:1018869601502
- Publisher site
- See Article on Publisher Site
Abstract
Purpose. Nasal delivery of protein therapeutics can be compromised by the brief residence time at this mucosal surface. Some bioadhesive polymers have been suggested to extend residence time and improve protein uptake across the nasal mucosa. We examined several potential polymer platforms for their in vitro protein release, relative bioadhesive properties and induction of cytokine release from respiratory epithelium.
Journal
Pharmaceutical Research – Springer Journals
Published: Sep 30, 2004