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References (38)
-
H. Hatakeyama, H. Akita, H. Harashima (2011)
A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma.Advanced drug delivery reviews, 63 3
-
S. Toyokuni, K. Okamoto, J. Yodoi, H. Hiai (1995)
Persistent oxidative stress in cancerFEBS Letters, 358
-
Martin Meyer, E. Wagner (2006)
Recent developments in the application of plasmid DNA-based vectors and small interfering RNA therapeutics for cancer.Human gene therapy, 17 11
-
N. Ganguly, S. Barik (2009)
A Facile Mild Deprotection Protocolfor 1,3-Dithianes and 1,3-Dithiolanes with 30% HydrogenPeroxide and Iodine Catalyst in Aqueous Micellar SystemSynthesis, 2009
-
N. Somia, I. Verma (2000)
Gene therapy: trials and tribulationsNature Reviews Genetics, 1
-
T. Merdan, J. Kopeček, T. Kissel (2002)
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer.Advanced drug delivery reviews, 54 5
-
N. Ganguly, P. Mondal (2011)
Mild, Efficient, and Greener Dethioacetalization Protocol Using 30% Hydrogen Peroxide in Catalytic Combination with Ammonium IodideSynthetic Communications, 41
-
D. Fischer, Youxin Li, B. Ahlemeyer, J. Krieglstein, T. Kissel (2003)
In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis.Biomaterials, 24 7
-
R. Roy, Jiang Yang, M. Moses (2009)
Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27 31
-
A. Shukla, M. Verma, K. Singh (2004)
Superoxide Induced Deprotection of 1,3-Dithiolanes: A Convenient Method of Dedithioacetalization.ChemInform, 35
-
D. Wilson, G. Dalmasso, Lixin Wang, S. Sitaraman, D. Merlin, N. Murthy (2010)
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines.Nature materials, 9 11
-
C. Anderson, E. Canning, B. Okamura (1998)
A triploblast origin for Myxozoa?Nature, 392
-
Clare Thomas, A. Ehrhardt, M. Kay (2003)
Progress and problems with the use of viral vectors for gene therapyNature Reviews Genetics, 4
-
R. Mulligan (1993)
The basic science of gene therapy.Science, 260 5110
-
T. Szatrowski, C. Nathan (1991)
Production of large amounts of hydrogen peroxide by human tumor cells.Cancer research, 51 3
-
Eun Lee, Zhong-gao Gao, Y. Bae (2008)
Recent progress in tumor pH targeting nanotechnology.Journal of controlled release : official journal of the Controlled Release Society, 132 3
-
D. Pack, A. Hoffman, S. Pun, P. Stayton (2005)
Design and development of polymers for gene deliveryNature Reviews Drug Discovery, 4
-
L. Rajendran, H. Knölker, K. Simons (2010)
Subcellular targeting strategies for drug design and deliveryNature Reviews Drug Discovery, 9
-
L. Medina-Kauwe, L. Medina-Kauwe, Jiansong Xie, S. Hamm-Alvarez (2005)
Intracellular trafficking of nonviral vectorsGene Therapy, 12
-
B. Genty, J. Briantais, N. Baker (1989)
The relationship between the quantum yield of photosynthetic electron transport and quenching of chlorophyll fluorescenceBiochimica et Biophysica Acta, 990
-
M. Ou, Xu-li Wang, R. Xu, Chien-Wen Chang, D. Bull, S. Kim (2008)
Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity.Bioconjugate chemistry, 19 3
-
B. Halliwell, M. Clément, L. Long (2000)
Hydrogen peroxide in the human bodyFEBS Letters, 486
-
Nathan Gabrielson, Hua Lu, Lichen Yin, Dong Li, Fei Wang, Jianjun Cheng (2012)
Reactive and bioactive cationic α-helical polypeptide template for nonviral gene delivery.Angewandte Chemie, 51 5
-
C. Alexander (2006)
Temperature- and pH-responsive smart polymers for gene deliveryExpert Opinion on Drug Delivery, 3
-
Nate Larson, A. Ray, A. Malugin, Daniel Pike, H. Ghandehari (2010)
HPMA Copolymer-Aminohexylgeldanamycin Conjugates Targeting Cell Surface Expressed GRP78 in Prostate CancerPharmaceutical Research, 27
-
Nathan Gabrielson, D. Pack (2006)
Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions.Biomacromolecules, 7 8
-
M. Arap, J. Lahdenranta, P. Mintz, A. Hajitou, Á. Sarkis, W. Arap, R. Pasqualini (2004)
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands.Cancer cell, 6 3
-
A. Feldman, S. Libutti (2000)
Progress in antiangiogenic gene therapy of cancerCancer, 89
-
D. Fischer, T. Bieber, Youxin Li, H. Elsässer, T. Kissel (1999)
A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and CytotoxicityPharmaceutical Research, 16
-
Peng Li, Donghua Liu, Lei Miao, Chunxi Liu, Xiaoli Sun, Yongjun Liu, N. Zhang (2012)
A pH-sensitive multifunctional gene carrier assembled via layer-by-layer technique for efficient gene deliveryInternational Journal of Nanomedicine, 7
-
Y. Oh, T. Park (2009)
siRNA delivery systems for cancer treatment.Advanced drug delivery reviews, 61 10
-
Q. Wu, T. Moyana, J. Xiang (2001)
Cancer gene therapy by adenovirus-mediated gene transfer.Current gene therapy, 1 1
-
K. Senthil, S. Aranganathan, N. Nalini (2004)
Evidence of oxidative stress in the circulation of ovarian cancer patients.Clinica chimica acta; international journal of clinical chemistry, 339 1-2
-
Rob Burke, S. Pun (2010)
Synthesis and characterization of biodegradable HPMA-oligolysine copolymers for improved gene delivery.Bioconjugate chemistry, 21 1
-
T. Park, J. Jeong, S. Kim (2006)
Current status of polymeric gene delivery systems.Advanced drug delivery reviews, 58 4
-
L. Brannon-Peppas, J. Blanchette (2004)
Nanoparticle and targeted systems for cancer therapy.Advanced drug delivery reviews, 56 11
-
B. Kumar, S. Koul, L. Khandrika, R. Meacham, H. Koul (2008)
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype.Cancer research, 68 6
-
H. Hatakeyama, H. Akita, K. Kogure, Motoi Oishi, Yukio Nagasaki, Y. Kihira, M. Ueno, H. Kobayashi, Hiroshi Kikuchi, H. Harashima (2007)
Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipidGene Therapy, 14
- Publisher
- Wiley
- Copyright
- Copyright © 2013 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 1433-7851
- eISSN
- 1521-3773
- DOI
- 10.1002/anie.201209633
- pmid
- 23716349
- Publisher site
- See Article on Publisher Site
Abstract
Stimuli‐responsive release: The high levels of reactive oxygen species (ROS) in prostate cancer cells can be exploited to trigger cancer‐targeted gene delivery. A ROS‐responsive thioketal‐based cationic polymer was synthesized and functionalization with a cancer‐targeting peptide led to selective and enhanced gene transfection in prostate cancer cells (see scheme).
Journal
Angewandte Chemie International Edition – Wiley
Published: Jan 1, 2013
Keywords: ; ; ;