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Correlation of Syntocinon Sensitivity and Uterine Response at Term with the Course of Induced Labour

Correlation of Syntocinon Sensitivity and Uterine Response at Term with the Course of Induced Labour BY P E N l T l A. JXRVINEN, TAPANI LUUKKAINEN A N D TAPANI PYdRXLX The determination of the optimal time for the induction of labour has been assessed, for example, by studying the condition of the cervix (C o c k s, I 955) or by using the Oxytocin Sensitivity Test ( N i x o n and S m y t h , 1 9 9 ;Smyth, 1958). This latter test was based on the assumption that the oxytocinase activity in blood would diminish with the imminence of labour. It was therefore thought possible to build up the higher concentration of oxytocin in the blood stream by giving the same minute amount of oxytocin at a constant rate of 0.01unit per minute. However, studies on the oxytocin inactivating enzyme have shown that the level of oxytocinase does not decrease with the imminence of labour ( T i t u s et al. 1960;T u p p y et al. 1961; M e n d e z - B a u e r et al. 1961) and the results of the oxytocin sensitivity test do not predict the onset of labour ( G o l t http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Obstetricia Et Gynecologica Scandinavica Wiley

Correlation of Syntocinon Sensitivity and Uterine Response at Term with the Course of Induced Labour

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Publisher
Wiley
Copyright
1964 Acta Obstet Gynecol Scand
ISSN
0001-6349
eISSN
1600-0412
DOI
10.3109/00016346409158176
Publisher site
See Article on Publisher Site

Abstract

BY P E N l T l A. JXRVINEN, TAPANI LUUKKAINEN A N D TAPANI PYdRXLX The determination of the optimal time for the induction of labour has been assessed, for example, by studying the condition of the cervix (C o c k s, I 955) or by using the Oxytocin Sensitivity Test ( N i x o n and S m y t h , 1 9 9 ;Smyth, 1958). This latter test was based on the assumption that the oxytocinase activity in blood would diminish with the imminence of labour. It was therefore thought possible to build up the higher concentration of oxytocin in the blood stream by giving the same minute amount of oxytocin at a constant rate of 0.01unit per minute. However, studies on the oxytocin inactivating enzyme have shown that the level of oxytocinase does not decrease with the imminence of labour ( T i t u s et al. 1960;T u p p y et al. 1961; M e n d e z - B a u e r et al. 1961) and the results of the oxytocin sensitivity test do not predict the onset of labour ( G o l t

Journal

Acta Obstetricia Et Gynecologica Scandinavica – Wiley

Published: Jan 1, 1964

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