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/lp/karger/new-views-on-the-identification-of-the-various-cell-types-in-the-EN0rC2oUkc
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- Publisher
- Karger
- Copyright
- © 1985 S. Karger AG, Basel
- ISSN
- 1422-6405
- eISSN
- 1422-6421
- DOI
- 10.1159/000145977
- Publisher site
- See Article on Publisher Site
Abstract
Islets of Langerhans taken from different parts of the pancreas have been studied ultrastructurally in adult rats. Five different islet cell types were identified in each islet with the aid of morphometrical analysis of their specific secretory granules. Previous immunohistochemical findings concerning the amount and location of insulin-, glucagon-, somatostatin- and pancreatic-polypeptide-containing cells and their ultrastructurally recognizable counterparts were compared, and it was possible to identify four main islet cell types with the electron microscope. Moreover, cells quite similar to the enterochromaffine cells described elsewhere in the exocrine pancreas and in the gastrointestinal tract were found to normally occur in the pancreatic islets of the rat.
Journal
Cells Tissues Organs – Karger
Published: Jan 1, 1985
Keywords: Rat pancreatic islets; Ultrastructure and morphometry