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STATE OF THE SCIENCE Pharmacologic Management of Osteoarthritis-Related Pain in Older Adults A review shows that many drug therapies provide small-to-modest pain relief. M. Carrington Reid ▼ Rouzi Shengelia ▼ Samantha J. Parker OVERVIEW: Because pain is a common and debilitating symp- can be effective, many patients (particularly older tom of osteoarthritis in older adults, the authors reviewed adults and racial or ethnic minorities) forgo it. This article synthesizes what we know about the data on the effi cacy and safety of commonly used oral, topi- pharmacologic management of OA-related pain in older cal, and intraarticular drug therapies in this population. A adults—those ages 65 and older. A focus on older adults search of several databases found that most studies have fo- is appropriate for several reasons. In this age group, un- cused on knee osteoarthritis and reported only short-term dertreated pain leads to poor self-rated health and outcomes. Also, treatment effi cacy was found to vary by drug 12,13 decreased cognition and mobility. Pain is by far the class; the smallest effect was observed with acetaminophen most frequently cited symptom causing disability in and the largest with opioids and viscosupplements. later life, threatening independence. Older adults’ rate Acetaminophen
Orthopaedic Nursing – Wolters Kluwer Health
Published: Mar 1, 2012
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