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Extracapsular spread of carcinoma in cervical lymph nodes impact upon survival in patients with carcinoma of the supraglottic larynx

Extracapsular spread of carcinoma in cervical lymph nodes impact upon survival in patients with... The treatment results and histologic findings in the cervical lymphatics of 96 patients with squamous cell carcinoma of the supraglottic larynx were studied retrospectively. The clinical assessment of the extent of disease in the cervical lymphatics correlated poorly with histologic findings. Forty‐one percent of patients judged to have no evidence of cervical metastases were found to have carcinoma in the cervical lymphatics. Twenty percent of patients judged clinically NO were found to have extracapsular spread of tumor. Patients were subdivided according to the histologic findings in the cervical lymphatics. Three‐year no‐evidence‐of‐disease (NED) follow‐up was available on all patients. Patients with no tumor in cervical lymphatics had a 71% 3‐year NED. By comparison, patients with cervical metastases confined to the lymph node were 79% NED. Patients with histologic evidence of extracapsular spread of tumor were 45% NED (P < 0.05). The use of histologic findings in predicting prognosis and treatment planning is discussed. Cancer 56: 1597‐1599, 1985. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cancer Wiley

Extracapsular spread of carcinoma in cervical lymph nodes impact upon survival in patients with carcinoma of the supraglottic larynx

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References (2)

Publisher
Wiley
Copyright
Copyright © 1985 American Cancer Society
ISSN
0008-543X
eISSN
1097-0142
DOI
10.1002/1097-0142(19851001)56:7<1597::AID-CNCR2820560722>3.0.CO;2-5
Publisher site
See Article on Publisher Site

Abstract

The treatment results and histologic findings in the cervical lymphatics of 96 patients with squamous cell carcinoma of the supraglottic larynx were studied retrospectively. The clinical assessment of the extent of disease in the cervical lymphatics correlated poorly with histologic findings. Forty‐one percent of patients judged to have no evidence of cervical metastases were found to have carcinoma in the cervical lymphatics. Twenty percent of patients judged clinically NO were found to have extracapsular spread of tumor. Patients were subdivided according to the histologic findings in the cervical lymphatics. Three‐year no‐evidence‐of‐disease (NED) follow‐up was available on all patients. Patients with no tumor in cervical lymphatics had a 71% 3‐year NED. By comparison, patients with cervical metastases confined to the lymph node were 79% NED. Patients with histologic evidence of extracapsular spread of tumor were 45% NED (P < 0.05). The use of histologic findings in predicting prognosis and treatment planning is discussed. Cancer 56: 1597‐1599, 1985.

Journal

Cancer – Wiley

Published: Oct 1, 1985

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