Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution

Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution 0021-972X/04/$15.00/0 The Journal of Clinical Endocrinology & Metabolism 89(6):2608 –2615 Printed in U.S.A. Copyright © 2004 by The Endocrine Society doi: 10.1210/jc.2004-0433 Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution DAVID E. CUMMINGS, JOOST OVERDUIN, AND KAREN E. FOSTER-SCHUBERT Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98195 Energy homeostasis and medical vs. surgical methods to pseudotumor cerebri, arthritis, infertility, stress inconti- overcome it nence, and venous stasis ulcers (4, 8, 9). The net effect is an increase in quality of life and decrease in overall mortality Obesity is now a global pandemic that continues to ac- (11, 12). Estimates of the cost of bariatric surgery per quality- celerate despite the often Herculean efforts by afflicted in- adjusted life year (QALY) range from $5,400 to $36,600/ dividuals to lose weight. These efforts are thwarted by a QALY, well under the $50,000/QALY benchmark that is physiological system that regulates body weight in a manner generally regarded in the United States as being cost effective analogous to that by which a thermostat controls ambient (13, 14). Unquestionably, obesity surgery is a drastic ap- temperature. For http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical Endocrinology and Metabolism Oxford University Press

Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution

Download PDF
8 pages

Loading next page...
 
/lp/oxford-university-press/gastric-bypass-for-obesity-mechanisms-of-weight-loss-and-diabetes-CcKKx08Wef

References (91)

Publisher
Oxford University Press
Copyright
Copyright © 2004 by The Endocrine Society
ISSN
0021-972X
eISSN
1945-7197
DOI
10.1210/jc.2004-0433
pmid
15181031
Publisher site
See Article on Publisher Site

Abstract

0021-972X/04/$15.00/0 The Journal of Clinical Endocrinology & Metabolism 89(6):2608 –2615 Printed in U.S.A. Copyright © 2004 by The Endocrine Society doi: 10.1210/jc.2004-0433 Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution DAVID E. CUMMINGS, JOOST OVERDUIN, AND KAREN E. FOSTER-SCHUBERT Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98195 Energy homeostasis and medical vs. surgical methods to pseudotumor cerebri, arthritis, infertility, stress inconti- overcome it nence, and venous stasis ulcers (4, 8, 9). The net effect is an increase in quality of life and decrease in overall mortality Obesity is now a global pandemic that continues to ac- (11, 12). Estimates of the cost of bariatric surgery per quality- celerate despite the often Herculean efforts by afflicted in- adjusted life year (QALY) range from $5,400 to $36,600/ dividuals to lose weight. These efforts are thwarted by a QALY, well under the $50,000/QALY benchmark that is physiological system that regulates body weight in a manner generally regarded in the United States as being cost effective analogous to that by which a thermostat controls ambient (13, 14). Unquestionably, obesity surgery is a drastic ap- temperature. For

Journal

Journal of Clinical Endocrinology and Metabolism – Oxford University Press

Published: Jun 1, 2004

There are no references for this article.