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Prenatal and Breast Milk Morphine Exposure Following Maternal Intrathecal Morphine Treatment

Prenatal and Breast Milk Morphine Exposure Following Maternal Intrathecal Morphine Treatment A case of an infant who had morphine exposure during and following pregnancy while her mother was treated with intrathecal (IT) morphine is presented along with a review of the relevant literature. Successful maternal pain management was achieved during pregnancy and while breastfeeding. Minimal maternal serum and breast milk levels in the first 7 postpartum weeks were found. Also, infant sleep and arousal behavior and general development at 2 and 7 months were unremarkable, illustrating the possible safe and efficacious use of IT morphine during and following pregnancy. Further work is required to understand opioid pharmacology during breastfeeding, which will be used to develop an empirical approach to breastfeeding and morphine use. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Human Lactation SAGE

Prenatal and Breast Milk Morphine Exposure Following Maternal Intrathecal Morphine Treatment

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References (24)

Publisher
SAGE
Copyright
Copyright © by SAGE Publications
ISSN
0890-3344
eISSN
1552-5732
DOI
10.1177/089033440001600210
pmid
11153344
Publisher site
See Article on Publisher Site

Abstract

A case of an infant who had morphine exposure during and following pregnancy while her mother was treated with intrathecal (IT) morphine is presented along with a review of the relevant literature. Successful maternal pain management was achieved during pregnancy and while breastfeeding. Minimal maternal serum and breast milk levels in the first 7 postpartum weeks were found. Also, infant sleep and arousal behavior and general development at 2 and 7 months were unremarkable, illustrating the possible safe and efficacious use of IT morphine during and following pregnancy. Further work is required to understand opioid pharmacology during breastfeeding, which will be used to develop an empirical approach to breastfeeding and morphine use.

Journal

Journal of Human LactationSAGE

Published: May 1, 2000

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