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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin The Sir2 family member SIRT6 is an NAD-dependent, histone H3 lysine 9 deacetylase enzyme that modulates telomeric chromatin and is required for stable association of WRN, the factor that is mutated in Werner Syndrome. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Springer Journals

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References (33)

Publisher
Springer Journals
Copyright
Copyright © 2008 by Nature Publishing Group
Subject
Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
ISSN
0028-0836
eISSN
1476-4687
DOI
10.1038/nature06736
Publisher site
See Article on Publisher Site

Abstract

The Sir2 family member SIRT6 is an NAD-dependent, histone H3 lysine 9 deacetylase enzyme that modulates telomeric chromatin and is required for stable association of WRN, the factor that is mutated in Werner Syndrome.

Journal

NatureSpringer Journals

Published: Mar 12, 2008

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