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S‐100 protein in granular cell tumors. (Granular cell myoblastomas)

S‐100 protein in granular cell tumors. (Granular cell myoblastomas) Outside the central nervous system S‐100 is found only in Schwann cells and satellite cells of ganglia. It has also been demonstrated in Schwannomas and neurofibromas but is absent from soft tissue tumors of non‐neural origin. S‐100 protein was looked for in granular cell myoblastomas using an immuno‐histochemical technique in an attempt to further elucidate the histogenesis of these tumors. All tumor cells in the ten tumors studied were intensely stained with antiserum to S‐100 including one with some malignant features. These results support the idea that granular cell myoblastomas arise from Schwann cells. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cancer Wiley

S‐100 protein in granular cell tumors. (Granular cell myoblastomas)

Cancer , Volume 49 (9) – May 1, 1982

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References (44)

Publisher
Wiley
Copyright
Copyright © 1982 American Cancer Society
ISSN
0008-543X
eISSN
1097-0142
DOI
10.1002/1097-0142(19820501)49:9<1834::AID-CNCR2820490916>3.0.CO;2-G
Publisher site
See Article on Publisher Site

Abstract

Outside the central nervous system S‐100 is found only in Schwann cells and satellite cells of ganglia. It has also been demonstrated in Schwannomas and neurofibromas but is absent from soft tissue tumors of non‐neural origin. S‐100 protein was looked for in granular cell myoblastomas using an immuno‐histochemical technique in an attempt to further elucidate the histogenesis of these tumors. All tumor cells in the ten tumors studied were intensely stained with antiserum to S‐100 including one with some malignant features. These results support the idea that granular cell myoblastomas arise from Schwann cells.

Journal

CancerWiley

Published: May 1, 1982

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