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Liver and Aging
- Publisher
- Springer Journals
- Copyright
- Copyright
- Subject
- Biomedicine; Pharmacology/Toxicology; Pharmacy; Veterinary Medicine/Veterinary Science; Biomedical Engineering and Bioengineering; Biochemistry, general
- ISSN
- 1567-567X
- DOI
- 10.1007/BF01061844
- Publisher site
- See Article on Publisher Site
Abstract
The phamacokinetic behavior of caffeine was compared in a group of eight healthy young men aged 20.5±2.0 years (mean ± SD), and in a group of eight healthy, elderly men aged 71.2±3.9 years. Each subject was given a 5 mg/kg dose of caffeine as either an aqueous oral solution or an intravenous infusion over 30 min using a randomized crossover design. Plasma and urine samples were collected for 24 hr following each dose and analyzed for caffeine content using high-performance liquid chromatography.
Journal
Journal of Pharmacokinetics and Pharmacodynamics – Springer Journals
Published: Apr 1, 1983