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References (24)
-
Y. Nagata, K. Todokoro (1994)
Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation.Biochemical and biophysical research communications, 199 3
-
J. Carmichael, W. Degraff, A. Gazdar, J. Minna, James Mitchell (1987)
Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.Cancer research, 47 4
-
M. Shibanuma, Toshio Kuroki, K. Nose (1992)
Isolation of a gene encoding a putative leucine zipper structure that is induced by transforming growth factor beta 1 and other growth factors.The Journal of biological chemistry, 267 15
-
Y. Chin, M. Kitagawa, Wu-Chou Su, Zhi-Hao You, Y. Iwamoto, Xin-Yuan Fu (1996)
Cell Growth Arrest and Induction of Cyclin-Dependent Kinase Inhibitor p21WAF1/CIP1 Mediated by STAT1Science, 272
-
M. Barone, A. Crozat, A. Tabaee, L. Philipson, D. Ron (1994)
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.Genes & development, 8 4
-
R. Benezra, R. Davis, D. Lockshon, D. Turner, H. Weintraub (1990)
The protein Id: A negative regulator of helix-loop-helix DNA binding proteinsCell, 61
-
Mitsunobu Sato, H. Kawamata, K. Harada, Koichi Nakashiro, Yoshikazu Ikeda, H. Gohda, H. Yoshida, T. Nishida, Kenji Ono, M. Kinoshita, M. Adachi (1997)
Induction of cyclin-dependent kinase inhibitor, p21WAF1, by treatment with 3,4-dihydro-6-[4-(3,4)-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinoline (vesnarinone) in a human salivary cancer cell line with mutant p53 gene.Cancer letters, 112 2
-
(1998)
C Cancer Research Campaign British Journal of Cancer -
A. Fornace, D. Nebert, M. Hollander, J. Luethy, M. Papathanasiou, J. Fargnoli, N. Holbrook (1989)
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agentsMolecular and Cellular Biology, 9
-
K. Hamil, S. Hall (1994)
Cloning of rat Sertoli cell follicle-stimulating hormone primary response complementary deoxyribonucleic acid: regulation of TSC-22 gene expression.Endocrinology, 134 3
-
(1994)
Constitutive expression of Id gene impairs mouse B cell development -
M. Sato, K. Harada, H. Yoshida (1994)
INDUCTION OF DIFFERENTIATION AND APOPTOSIS, AND Ley ANTIGEN EXPRESSION BY TREATMENT WITH 3, 4-DIHYDRO-6-[4-(3, 4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (VESNARINONE) IN A HUMAN SALIVARY CANCER CELL LINEActa Histochemica Et Cytochemica, 27
-
(1994)
The expression pattern of ld4, a novel dominant negative helix-loop-helix protein, is distinct from Id 1, Id2, and Wd3 -
Mitsunobu Sato, K. Harada, T. Bando, Tetsuya Shirakami, Koichi Nakashiro, H. Yoshida, S. Nakai, K. Kawai, M. Adachi (1995)
Characteristics of antitumor activity of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]- 2(1H)-quinolinone (vesnarinone) against a human adenoid squamous carcinoma-forming cell line grown in athymic nude mice.Cancer letters, 91 1
-
D. Ron, J. Habener (1992)
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.Genes & development, 6 3
-
J. Auwerx, P. Sassone-Corsi (1991)
IP-1: A dominant inhibitor of Fos/Jun whose activity is modulated by phosphorylationCell, 64
-
T. Yanagawa, Y. Hayashi, H. Yoshida, Y. Yura, S. Nagamine, T. Bando, M. Sato (1986)
An adenoid squamous carcinoma-forming cell line established from an oral keratinizing squamous cell carcinoma expressing carcinoembryonic antigen.The American journal of pathology, 124 3
-
M. Barone, R. Pepperkok, F. Peverali, L. Philipson (1994)
Id proteins control growth induction in mammalian cells.Proceedings of the National Academy of Sciences of the United States of America, 91 11
-
Jong Park, J. Luethy, Mary Wang, J. Fargnoli, A. Fornace, O. McBride, N. Holbrook (1992)
Isolation, characterization and chromosomal localization of the human GADD153 gene.Gene, 116 2
-
H. Asanoi, S. Sasayama, K. Iuchi, T. Kameyama (1987)
Acute hemodynamic effects of a new inotropic agent (OPC-8212) in patients with congestive heart failure.Journal of the American College of Cardiology, 9 4
-
(1998)
British Journal of Cancer C Cancer Research Campaign -
P. Jay, J. Ji, C. Marsollier, S. Taviaux, J. Bergé-Lefranc, P. Berta (1996)
Cloning of the Human Homologue of the TGFβ-Stimulated Clone 22 GeneBiochemical and Biophysical Research Communications, 222
-
(1992)
p2lWAFl, by treatment -
(1994)
Doxorubicin represses the function of myogenic helix-loop-helix transcription factor MyoD
- Publisher
- Springer Journals
- Copyright
- Copyright © 1998 by Cancer Research Campaign
- Subject
- Biomedicine; Biomedicine, general; Cancer Research; Epidemiology; Molecular Medicine; Oncology; Drug Resistance
- ISSN
- 0007-0920
- eISSN
- 1532-1827
- DOI
- 10.1038/bjc.1998.11
- Publisher site
- See Article on Publisher Site
Abstract
We undertook the present study to clarify the molecular mechanism of the effect of a new anti-cancer drug, vesnarinone, on a human salivary gland cancer cell line, TYS. We isolated TSC-22cDNA as avesnarinone-inducible gene from a cDNA library constructed from vesnarinone-treated TYS cells. TSC-22 was originally reported as a transforming growth factor (TGF)-beta-inducible gene. The expression of TSC-22 was up-regulated within a few hours after treatment with vesnarinone and was continued for 3 days. The level of TSC-22 mRNA in TYS cells was continuously increased until the cells reached confluency. Furthermore, the induction of TSC-22 by vesnarinone was inhibited by treatment with cycloheximide. When we treated the cells with an antisense oligonucleotide against TSC-22 mRNA under quiescent conditions, the antisense oligonucleotide stimulated the growth of TYS cells; however, under growing conditions the antisense oligonucleotide did not affect cell growth. Furthermore, the antisense oligonucleotide suppressed the antiproliferative effect of vesnarinone. These results suggest that TSC-22 may be a negative growth regulator and may play an important role in the antiproliferative effect of vesnarinone.
Journal
British Journal of Cancer – Springer Journals
Published: Jan 1, 1998