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Volume 63, Number 2 OBSTETRICAL AND GYNECOLOGICAL SURVEY Copyright © 2008 by Lippincott Williams & Wilkins GYNECOLOGY A UK Multicenter Retrospective Cohort Study Comparing Hysterectomy and Uterine Artery Embolization for the Treatment of Symptomatic Uterine Fibroids (HOPEFUL Study): Main Results on Medium-term Safety and Efficacy S. Dutton, A. Hirst, K. McPherson, T. Nicholson, and M. Maresh Centre for Statistics in Medicine, Wolfson College, University of Oxford and CTSU, University of Oxford, Oxford, United Kingdom; Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, United Kingdom; Department of Radiology, Leeds General Infirmary, Leeds, United Kingdom; and Department of Obstetrics and Gynaecology St. Mary’s Hospital for Women and Children, Central Manchester and Manchester Children’s University Hospitals NHS Trust, Manchester, United Kingdom BJOG 2007;114:1340–1351 ABSTRACT The Hysterectomy Or Percutaneous Embolization For Uterine Leiomyomata (HOPEFUL) study was an attempt to compare the effectiveness, safety, and cost-effectiveness of 2 methods of treating symptomatic uterine fibroids, hysterectomy, and uterine artery embolization (UAE). The multicenter retrospective cohort study enrolled 459 women having hysterectomy and followed-up for 8.6 years on average, and 649 others who underwent UAE and were followed for 4.6 years on average. A majority of hysterectomies were total abdominal procedures. Complications were more
Obstetrical & Gynecological Survey – Wolters Kluwer Health
Published: Feb 1, 2008
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