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- Publisher
- Springer Journals
- Copyright
- Copyright © 1997 by Nature Publishing Group
- Subject
- Life Sciences; Life Sciences, general; Biochemistry, general; Protein Structure; Membrane Biology; Biological Microscopy
- ISSN
- 1545-9993
- eISSN
- 1545-9985
- DOI
- 10.1038/nsb0997-686
- Publisher site
- See Article on Publisher Site
Abstract
RasGAPs supply a catalytic residue, termed the arginine finger, into the active site of Ras thereby stabilizing the transition state of the GTPase reaction and increasing the reaction rate by more than one thousand-fold, in good agreement with the structure of the RasṁRasGAP complex.
Journal
Nature Structural & Molecular Biology – Springer Journals
Published: Sep 1, 1997