Access the full text.
Sign up today, get DeepDyve free for 14 days.
F. Giardiello, Steven Welsh, S. Hamilton, G. Offerhaus, A. Gittelsohn, S. Booker, A. Krush, J. Yardley, G. Luk (1987)
Increased risk of cancer in the Peutz-Jeghers syndrome.The New England journal of medicine, 316 24
J. Utsunomiya, H. Gocho, T. Miyanaga, E. Hamaguchi, A. Kashimure (1975)
Peutz-Jeghers syndrome: its natural course and management.The Johns Hopkins medical journal, 136 2
A. Hemminki, I. Tomlinson, D. Markie, H. Järvinen, P. Sistonen, Anna‐Maria Björkqvist, S. Knuutila, R. Salovaara, W. Bodmer, D. Shibata, A. Chapelle, L. Aaltonen (1997)
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysisNature Genetics, 15
A. Spigelman, V. Murday, R. Phillips (1989)
Cancer and the Peutz-Jeghers syndrome.Gut, 30
V. Launonen, E. Avizienyte, A. Loukola, P. Laiho, R. Salovaara, H. Järvinen, J. Mecklin, A. Oku, M. Shimane, H. Kim, Jin Kim, J. Nezu, L. Aaltonen (2000)
No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas.Cancer research, 60 3
K. Quon, A. Berns (2001)
Haplo-insufficiency? Let me count the ways.Genes & development, 15 22
N. Shepherd, H. Bussey, J. Jass (1987)
Epithelial Misplacement in Peutz-Jeghers Polyps: A Diagnostic PitfallThe American Journal of Surgical Pathology, 11
Masahiko Taniguchi, M. Sanbo, Satoshi Watanabe, Ichiro Naruse, Masayoshi Mishina, Takeshi Yagi (1998)
Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: a transient gene-integration marker for ES cells.Nucleic acids research, 26 2
A. Ylikorkala, Derrick Rossi, Nina Korsisaari, K. Luukko, K. Alitalo, M. Henkemeyer, T. Mäkelä (2001)
Vascular Abnormalities and Deregulation of VEGF in Lkb1-Deficient MiceScience, 293
J. Nezu, A. Oku, M. Shimane (1999)
Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients.Biochemical and biophysical research communications, 261 3
M. Oshima, H. Oshima, Kyoko Kitagawa, Masahiko Kobayashi, Chitoshi Itakura, M. Taketo (1995)
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene.Proceedings of the National Academy of Sciences of the United States of America, 92 10
I. Tomlinson, R. Houlston (1964)
PEUTZ‐JEGHERS SYNDROMEMedical Journal of Australia, 1
N. Lindor, M. Greene (1998)
The Concise Handbook of Family Cancer SyndromesJournal of the National Cancer Institute, 90
S. Olschwang, l9pl, S. Olschwang, David Markie, Sheila Seal, Kay Neale, Robin Phillips, Sally Cottrell, Ian Ellis, Shirley Hodgson, Peter Zauber, Allan Spigelman, Takeo Iwama, Steffan Loff, Carole McKeown, Cristiana Marchese, Julian Sampson, Sally Davies, Ian Talbot, J. Wyke, Gilles Thomas, W. Bodmer, A. Hemminki, E. Avizienyte, A. Chapelle, L. Aaltonen, Michael Stratton, R. Houlston, Ian Tomlinson (1998)
Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3.Journal of Medical Genetics, 35
S. Olschwang, C. Boisson, G. Thomas (2001)
Peutz-Jeghers families unlinked toSTK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinomaJournal of Medical Genetics, 38
P. Karuman, O. Gozani, R. Odze, X. Zhou, Hong Zhu, R. Shaw, T. Brien, Christopher Bozzuto, D. Ooi, L. Cantley, Junying Yuan (2001)
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.Molecular cell, 7 6
A. Hemminki, D. Markie, I. Tomlinson, E. Avizienyte, S. Roth, A. Loukola, G. Bignell, W. Warren, M. Aminoff, P. Höglund, H. Järvinen, P. Kristo, K. Pelin, M. Ridanpää, R. Salovaara, T. Toro, W. Bodmer, S. Olschwang, A. Olsen, M. Stratton, A. Chapelle, L. Aaltonen (1998)
A serine/threonine kinase gene defective in Peutz–Jeghers syndromeNature, 391
Takeshi Yagi, S. Nada, N. Watanabe, H. Tamemoto, N. Kohmura, Y. Ikawa, S. Aizawa (1993)
A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene.Analytical biochemistry, 214 1
H. Shibata, K. Toyama, H. Shioya, Masaki Ito, M. Hirota, S. Hasegawa, H. Matsumoto, H. Takano, T. Akiyama, K. Toyoshima, Ryunosuke Kanamaru, Y. Kanegae, I. Saito, Y. Nakamura, Kiyotaka Shiba, T. Noda (1997)
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.Science, 278 5335
I. Godin, F. Dieterlen-Lièvre, A. Cumano (1995)
Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus.Proceedings of the National Academy of Sciences of the United States of America, 92 3
D. Jenne, Heike Reomann, J. Nezu, W. Friedel, S. Loff, R. Jeschke, O. Müller, W. Back, M. Zimmer (1998)
Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinaseNature Genetics, 18
H. Miyoshi, M. Nakau, T. Ishikawa, M. Seldin, M. Oshima, M. Taketo (2002)
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.Cancer research, 62 8
M. Esteller, E. Avizienyte, P. Corn, R. Lothe, S. Baylin, L. Aaltonen, J. Herman (2000)
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndromeOncogene, 19
K. Luukko, A. Ylikorkala, M. Tiainen, T. Mäkelä (1999)
Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic developmentMechanisms of Development, 83
Y. Sato, K. Mukai, S. Watanabe, Masahiro Goto, Yukio Shimosaio (1986)
The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining.The American journal of pathology, 125 3
R. Estrada, H. Spjut (1983)
Hamartomatous polyps in Peutz‐Jeghers syndrome: A light‐, histochemical, and electron‐microscopic studyThe American Journal of Surgical Pathology, 7
Proceedings of the National Academy of Sciences – Unpaywall
Published: Jun 11, 2002
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.