S. Kohlhaas, O. Garden, C. Scudamore, M. Turner, K. Okkenhaug, E. Vigorito (2009)
Regulatory T Cells Contributes to the Development of Cutting Edge: The Foxp3 Target miR-155
K. Jażdżewski, Elizabeth Murray, K. Franssila, B. Jarzab, Daniel Schoenberg, A. Chapelle (2008)
Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinomaProceedings of the National Academy of Sciences, 105
Graham Lord, R. Rao, H. Choe, B. Sullivan, A. Lichtman, F. Luscinskas, L. Glimcher (2005)
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.Blood, 106 10
M. Gavin, J. Rasmussen, J. Fontenot, V. Vasta, V. Manganiello, J. Beavo, A. Rudensky (2007)
Foxp3-dependent programme of regulatory T-cell differentiationNature, 445
(1993)
J. Exp. Med
J. Barbi, S. Oghumu, C. Lezama-Dávila, A. Satoskar (2007)
IFN-γ and STAT1 are required for efficient induction of CXC chemokine receptor 3 (CXCR3) on CD4+ but not CD8+ T cellsBlood, 110
J. Siebler, S. Wirtz, S. Klein, M. Protschka, M. Blessing, P. Galle, M. Neurath (2003)
A key pathogenic role for the STAT1/T‐bet signaling pathway in T‐cell–mediated liver inflammationHepatology, 38
Li-Fan Lu, A. Rudensky (2009)
Molecular orchestration of differentiation and function of regulatory T cells.Genes & development, 23 11
Qi-jing Li, J. Chau, Peter Ebert, Giselle Sylvester, Hyeyoung Min, Gwen Liu, Ravi Braich, M. Manoharan, Juergen Soutschek, Petra Skare, L. Klein, Mark Davis, Chang‐Zheng Chen (2007)
miR-181a Is an Intrinsic Modulator of T Cell Sensitivity and SelectionCell, 129
A. Marson, Karsten Kretschmer, G. Frampton, Elizabeth Jacobsen, J. Polansky, K. MacIsaac, S. Levine, E. Fraenkel, H. Boehmer, R. Young (2007)
Foxp3 occupancy and regulation of key target genes during T-cell stimulationNature, 445
L. Williams, A. Rudensky (2007)
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3Nature Immunology, 8
T. Thai, D. Calado, S. Casola, K. Ansel, Changchun Xiao, Yingzi Xue, A. Murphy, D. Frendewey, D. Valenzuela, J. Kutok, M. Schmidt-Supprian, N. Rajewsky, G. Yancopoulos, A. Rao, K. Rajewsky (2007)
Regulation of the Germinal Center Response by MicroRNA-155Science, 316
J. Cameron, Qinyan Yin, Claire Fewell, M. Lacey, J. McBride, Xia Wang, Zhen Lin, B. Schaefer, E. Flemington (2007)
Epstein-Barr Virus Latent Membrane Protein 1 Induces Cellular MicroRNA miR-146a, a Modulator of Lymphocyte Signaling PathwaysJournal of Virology, 82
Kohlhaas (2009)
Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cellsJ. Immunol., 182
L. Bradley (2009)
Faculty Opinions recommendation of The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation.
Niclas Jonzén, Andreas Lindén, Torbjørn Ergon, E. Knudsen, J. Vik, Diego Rubolini, D. Piacentini, Christian Brinch, Fernando Spina, Lennart Karlsson, Martin Stervander, Arne Andersson, Jonas Waldenström, A. Lehikoinen, Erik Edvardsen, Rune Solvang, N. Stenseth (2003)
Supporting Online Material
A. Keegan (2009)
Faculty Opinions recommendation of Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses.
Urmila Maitra, S. Davis, C. Reilly, Liwu Li (2009)
Differential Regulation of Foxp3 and IL-17 Expression in CD4 T Helper Cells by IRAK-11The Journal of Immunology, 182
R. Khattri, T. Cox, Sue-Ann Yasayko, F. Ramsdell (2003)
An essential role for Scurfin in CD4+CD25+ T regulatory cellsNature Immunology, 4
J. Hou, Pin Wang, Li Lin, Xingguang Liu, Feng Ma, Huazhang An, Zhugang Wang, Xuetao Cao (2009)
MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK21The Journal of Immunology, 183
Bo Huang, Jie Zhao, Z. Lei, Shiqian Shen, Dong Li, G. Shen, Gui-mei Zhang, Zuo-hua Feng (2009)
miR‐142‐3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNAEMBO reports, 10
(2008)
IL-10 produced by regulatory T cells contributes to their suppressor function by limiting inflammation
C. Hsieh, Ye Zheng, Yuqiong Liang, J. Fontenot, A. Rudensky (2006)
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoiresNature Immunology, 7
Wen Lin, Dipica Haribhai, Lance Relland, Nga Truong, M. Carlson, C. Williams, T. Chatila (2007)
Regulatory T cell development in the absence of functional Foxp3Nature Immunology, 8
Silvia Monticelli, Silvia Monticelli, K. Ansel, Changchun Xiao, N. Socci, Anna Krichevsky, T. Thai, N. Rajewsky, D. Marks, C. Sander, K. Rajewsky, A. Rao, Kenneth Kosik, Kenneth Kosik (2005)
MicroRNA profiling of the murine hematopoietic systemGenome Biology, 6
Xuyu Zhou, Samantha Bailey-bucktrout, L. Jeker, C. Penaranda, M. Martínez‐Llordella, Meredith Ashby, M. Nakayama, Wendy Rosenthal, J. Bluestone (2009)
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivoNature Immunology, 10
Ye Zheng, Steven Josefowicz, A. Kas, Tin-Tin Chu, M. Gavin, A. Rudensky (2007)
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cellsNature, 445
S. Sakaguchi (2005)
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-selfNature Immunology, 6
Xiaoyu Hu, L. Ivashkiv (2009)
Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.Immunity, 31 4
Jiro Horino, M. Fujimoto, F. Terabe, S. Serada, Tsuyoshi Takahashi, Yoshihito Soma, Kentaro Tanaka, T. Chinen, A. Yoshimura, S. Nomura, I. Kawase, N. Hayashi, T. Kishimoto, T. Naka (2008)
Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice.International immunology, 20 6
Y. Rubtsov, J. Rasmussen, E. Chi, J. Fontenot, L. Castelli, X. Ye, P. Treuting, Lisa Siewe, Axel Roers, W. Henderson, Werner Müller, A. Rudensky (2008)
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.Immunity, 28 4
J. Marine, D. Topham, C. Mckay, Demin Wang, E. Parganas, D. Stravopodis, A. Yoshimura, J. Ihle (1999)
SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal LethalityCell, 98
B. Cobb, Arnulf Hertweck, James Smith, Eric O'Connor, D. Graf, Terence Cook, S. Smale, S. Sakaguchi, F. Livesey, A. Fisher, M. Merkenschlager (2006)
A role for Dicer in immune regulationThe Journal of Experimental Medicine, 203
Xuyu Zhou, L. Jeker, B. Fife, Shirley Zhu, Mark Anderson, Michael McManus, J. Bluestone (2008)
Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunityThe Journal of Experimental Medicine, 205
J. Barbi, S. Oghumu, C. Lezama-Dávila, A. Satoskar (2007)
IFN-gamma and STAT1 are required for efficient induction of CXC chemokine receptor 3 (CXCR3) on CD4+ but not CD8+ T cells.Blood, 110 6
M. Chong, J. Rasmussen, A. Rudensky, D. Littman (2008)
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory diseaseThe Journal of Experimental Medicine, 205
M. Meraz, J. White, K. Sheehan, E. Bach, S. Rodig, A. Dighe, D. Kaplan, J. Riley, A. Greenlund, Dayle Campbell, K. Carver-Moore, R. Dubois, R. Clark, M. Aguet, R. Schreiber (1996)
Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling PathwayCell, 84
G. Curtale, F. Citarella, C. Carissimi, Marina Goldoni, N. Carucci, V. Fulci, Debora Franceschini, F. Meloni, V. Barnaba, G. Macino (2010)
An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes.Blood, 115 2
Hori (2003)
Control of regulatory T cell development by the transcription factor Foxp3Science, 299
K. Beima, Michael Miazgowicz, Megan Lewis, P. Yan, T. Huang, A. Weinmann (2006)
T-bet Binding to Newly Identified Target Gene Promoters Is Cell Type-independent but Results in Variable Context-dependent Functional Effects*♦Journal of Biological Chemistry, 281
J. Fontenot, M. Gavin, A. Rudensky (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsNature Immunology, 4
A. Chaudhry, D. Rudra, P. Treuting, R. Samstein, Yuqiong Liang, A. Kas, A. Rudensky (2009)
CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent MannerScience, 326
Koch (2009)
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammationNat. Immunol., 10
Y. Zhan, G. Davey, K. Graham, Hiu Kiu, N. Dudek, T. Kay, A. Lew (2009)
SOCS1 negatively regulates the production of Foxp3+ CD4+ T cells in the thymusImmunology and Cell Biology, 87
Li-Fan Lu, T. Thai, D. Calado, A. Chaudhry, M. Kubo, Kentaro Tanaka, Gabriel Loeb, Hana Lee, A. Yoshimura, K. Rajewsky, A. Rudensky (2009)
Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein.Immunity, 30 1
J. Kim, J. Rasmussen, A. Rudensky (2007)
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceNature Immunology, 8
A. Lal, Francisco Navarro, C. Maher, L. Maliszewski, Nan Yan, Elizabeth O'Day, Dipanjan Chowdhury, D. Dykxhoorn, Perry Tsai, Oliver Hofmann, K. Becker, M. Gorospe, Winston Hide, J. Lieberman (2009)
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements.Molecular cell, 35 5
Caifu Chen, Dana Ridzon, A. Broomer, Zhaohui Zhou, Danny Lee, Julie Nguyen, M. Barbisin, Nanlan Xu, Vikram Mahuvakar, M. Andersen, K. Lao, K. Livak, K. Guegler (2005)
Real-time quantification of microRNAs by stem–loop RT–PCRNucleic Acids Research, 33
C. Nakajima, T. Mukai, N. Yamaguchi, Yasunari Morimoto, W. Park, M. Iwasaki, P. Gao, S. Ono, H. Fujiwara, T. Hamaoka (2002)
Induction of the chemokine receptor CXCR3 on TCR‐stimulated T cells: dependence on the release from persistent TCR‐triggering and requirement for IFN‐γ stimulationEuropean Journal of Immunology, 32
A. Liston, Li-Fan Lu, D. O’Carroll, A. Tarakhovsky, A. Rudensky (2008)
Dicer-dependent microRNA pathway safeguards regulatory T cell functionThe Journal of Experimental Medicine, 205
J. Schmitz, A. Owyang, E. Oldham, Yaoli Song, E. Murphy, T. Mcclanahan, G. Zurawski, M. Moshrefi, J. Qin, Xiaoxia Li, D. Gorman, J. Bazan, R. Kastelein, Schering-Plough Biopharma (2005)
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines.Immunity, 23 5
J. Fontenot, J. Rasmussen, L. Williams, James Dooley, A. Farr, A. Rudensky (2005)
Regulatory T cell lineage specification by the forkhead transcription factor foxp3.Immunity, 22 3
S. Ben-Sasson, J. Hu‐Li, Juan Quiel, Stephane Cauchetaux, M. Ratner, I. Shapira, C. Dinarello, W. Paul (2009)
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiationProceedings of the National Academy of Sciences, 106
Yeonseok Chung, S. Chang, G. Martinez, Xuexian Yang, R. Nurieva, H. Kang, Li Ma, S. Watowich, A. Jetten, Qiang Tian, C. Dong (2009)
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling.Immunity, 30 4
K. Taganov, M. Boldin, Kuang-Jung Chang, D. Baltimore (2006)
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesProceedings of the National Academy of Sciences, 103
Y. Belkaid, K. Tarbell (2009)
Regulatory T cells in the control of host-microorganism interactions (*).Annual review of immunology, 27
Ryan O’Connell, K. Taganov, M. Boldin, G. Cheng, D. Baltimore (2007)
MicroRNA-155 is induced during the macrophage inflammatory responseProceedings of the National Academy of Sciences, 104
Ariadne Androulidaki, D. Iliopoulos, A. Arranz, Christina Doxaki, Steffen Schworer, V. Zacharioudaki, A. Margioris, P. Tsichlis, C. Tsatsanis (2009)
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs.Immunity, 31 2
M. Kubo, T. Hanada, A. Yoshimura (2003)
Suppressors of cytokine signaling and immunityNature Immunology, 4
Yuanjia Tang, Xiaobing Luo, H. Cui, X. Ni, Min Yuan, Yanzhi Guo, Xin-fang Huang, Haibo Zhou, N. Vries, P. Tak, Shun‐le Chen, N. Shen (2009)
MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins.Arthritis and rheumatism, 60 4
Kentaro Tanaka, K. Ichiyama, Masayuki Hashimoto, H. Yoshida, T. Takimoto, G. Takaesu, T. Torisu, T. Hanada, H. Yasukawa, S. Fukuyama, H. Inoue, Y. Nakanishi, Takashi Kobayashi, A. Yoshimura (2008)
Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-γ on STAT3 and Smads1The Journal of Immunology, 180
Phenotypic Analysis of miR-146a-Deficient Mice
田中 謙太郎 (2009)
Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-γ on STAT3 and Smads
Zheng (2009)
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responsesNature, 458
W. Alexander, R. Starr, Jennifer Fenner, C. Scott, E. Handman, N. Sprigg, J. Corbin, A. Cornish, R. Darwiche, C. Owczarek, T. Kay, N. Nicola, P. Hertzog, D. Metcalf, D. Hilton (1999)
SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this CytokineCell, 98
G. Oldenhove, N. Bouladoux, E. Wohlfert, J. Hall, David Chou, L. Santos, S. O’Brien, R. Blank, E. Lamb, Sundar Natarajan, R. Kastenmayer, C. Hunter, M. Grigg, Y. Belkaid (2009)
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection.Immunity, 31 5
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