Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Ante—natal Prediction of ABO Haemolytic Disease

Ante—natal Prediction of ABO Haemolytic Disease Ante-natal Prediction of ABO Haemolytic Disease G. H. TOVEY, W. LOCKYER, N. BLADES J. A. AND H. C. G. FLAVELL South- Western Blood Transfusion Centre, Bristol and the Dorset County Laboratory, Dorchester ABO HAEMOLYTIC diseasc of the newborn occurs as commonly as Rh haemolytic diseasc and complicates about one in zoo pregnancies (Hsia and Gellis, 1954). It is not, however, usually as severe and the affectcd baby does not often requirc exchange transfusion. Any procedurc for its ante-natal prediction must therefore not only select those mothcrs who are carrying an affectcd baby, but should also indicate the probable severity and thus whether the mother should be delivered in a hospital equipped to give an exchange transfusion to the baby. Crawford, Cutbush aiid Mollison (1953) established that anti-A or anti-B hacinolysins are present in the serum of a mother who is carrying an affected baby and Lockyer aiid Tovey (1960) have devcloped a simplc single-tubc test, using group A cells from thc pig, so-called AP cells, to detect strong haemolysins. The application of this test, together with an antibody-absorption technique, as a routine procedure for the prediction of A 3 0 haemolytic disease forms the basis of the present http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png British Journal of Haematology Wiley

Ante—natal Prediction of ABO Haemolytic Disease

Download PDF
7 pages

Loading next page...
 
/lp/wiley/ante-natal-prediction-of-abo-haemolytic-disease-5dfhFj0cDI

References (20)

Publisher
Wiley
Copyright
Copyright © 1962 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0007-1048
eISSN
1365-2141
DOI
10.1111/j.1365-2141.1962.tb06518.x
Publisher site
See Article on Publisher Site

Abstract

Ante-natal Prediction of ABO Haemolytic Disease G. H. TOVEY, W. LOCKYER, N. BLADES J. A. AND H. C. G. FLAVELL South- Western Blood Transfusion Centre, Bristol and the Dorset County Laboratory, Dorchester ABO HAEMOLYTIC diseasc of the newborn occurs as commonly as Rh haemolytic diseasc and complicates about one in zoo pregnancies (Hsia and Gellis, 1954). It is not, however, usually as severe and the affectcd baby does not often requirc exchange transfusion. Any procedurc for its ante-natal prediction must therefore not only select those mothcrs who are carrying an affectcd baby, but should also indicate the probable severity and thus whether the mother should be delivered in a hospital equipped to give an exchange transfusion to the baby. Crawford, Cutbush aiid Mollison (1953) established that anti-A or anti-B hacinolysins are present in the serum of a mother who is carrying an affected baby and Lockyer aiid Tovey (1960) have devcloped a simplc single-tubc test, using group A cells from thc pig, so-called AP cells, to detect strong haemolysins. The application of this test, together with an antibody-absorption technique, as a routine procedure for the prediction of A 3 0 haemolytic disease forms the basis of the present

Journal

British Journal of Haematology – Wiley

Published: Jul 1, 1962

There are no references for this article.