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- Publisher
- Wiley
- Copyright
- Copyright © 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
- ISSN
- 1433-7851
- eISSN
- 1521-3773
- DOI
- 10.1002/anie.200503720
- pmid
- 16402415
- Publisher site
- See Article on Publisher Site
Abstract
Distance determination: A double electron electron resonance (DEER) measurement of a distance of 6.1 nm (green lines) between singly nitroxide‐labeled human von Willebrand Factor A domains demonstrates oligomerization of this domain in dilute solution (see structure); probably in an arrangement similar to that observed in the crystal structure. The DEER technique should be generally applicable for characterizing noncovalent interactions between macromolecules in solution.
Journal
Angewandte Chemie International Edition – Wiley
Published: Feb 6, 2006