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LiteMol suite: interactive web-based visualization of large-scale macromolecular structure data

LiteMol suite: interactive web-based visualization of large-scale macromolecular structure data CORRESPONDENCE visualization of large macromolecular data sets and speed that is LiteMol suite: interactive web- orders of magnitude faster than that of previously available solu- tions (Supplementary Notes 2 and 3). The LiteMol suite works based visualization of large-scale on all modern web browsers and mobile devices, and this makes macromolecular structure data macromolecular structure data available to diverse communities of users with and without structural biology expertise. To the Editor: We present the LiteMol suite, a tool for visualizing The data delivery services can dynamically extract subsets of large macromolecular structure data sets that is freely available at coordinate and experimental data to substantially reduce the https://www.litemol.org. network transfer size. CoordinateServer uses a rich molecular Given rapid advances in electron microscopy and other tech- query language to select only those atomic coordinates neces- niques for determining macromolecular structure, many struc- sary for the requested visualization (e.g., a ligand-binding site). tures that were previously intractable on account of their size DensityServer provides experimental maps (e.g., from X-ray or and complexity are now amenable to study at the molecular level. cryo-electron microscopy experiments) as a full-resolution slice Interactive web-based visualizations that include underlying (e.g., around a ligand) for a detailed http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Methods Springer Journals

LiteMol suite: interactive web-based visualization of large-scale macromolecular structure data

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References (6)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Life Sciences; Life Sciences, general; Biological Techniques; Biological Microscopy; Biomedical Engineering/Biotechnology; Bioinformatics; Proteomics
ISSN
1548-7091
eISSN
1548-7105
DOI
10.1038/nmeth.4499
Publisher site
See Article on Publisher Site

Abstract

CORRESPONDENCE visualization of large macromolecular data sets and speed that is LiteMol suite: interactive web- orders of magnitude faster than that of previously available solu- tions (Supplementary Notes 2 and 3). The LiteMol suite works based visualization of large-scale on all modern web browsers and mobile devices, and this makes macromolecular structure data macromolecular structure data available to diverse communities of users with and without structural biology expertise. To the Editor: We present the LiteMol suite, a tool for visualizing The data delivery services can dynamically extract subsets of large macromolecular structure data sets that is freely available at coordinate and experimental data to substantially reduce the https://www.litemol.org. network transfer size. CoordinateServer uses a rich molecular Given rapid advances in electron microscopy and other tech- query language to select only those atomic coordinates neces- niques for determining macromolecular structure, many struc- sary for the requested visualization (e.g., a ligand-binding site). tures that were previously intractable on account of their size DensityServer provides experimental maps (e.g., from X-ray or and complexity are now amenable to study at the molecular level. cryo-electron microscopy experiments) as a full-resolution slice Interactive web-based visualizations that include underlying (e.g., around a ligand) for a detailed

Journal

Nature Methods – Springer Journals

Published: Dec 1, 2017

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