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Uveitis and Pseudojaundice During a Regimen of Clarithromycin, Rifabutin, and Ethambutol

Uveitis and Pseudojaundice During a Regimen of Clarithromycin, Rifabutin, and Ethambutol To the Editor: We report the occurrence of uveitis and pseudojaundice in patients with AIDS who were receiving the combination of clarithromycin, rifabutin, and ethambutol for the treatment of Mycobacterium avium complex bacteremia. We are conducting a prospective, randomized, multicenter study comparing two oral multidrug regimens for the treatment of M. avium complex bacteremia in adults with AIDS. As of November 5, 1993, 119 patients had entered this study, 59 of whom were assigned to receive a regimen consisting of 1000 mg of clarithromycin twice daily, 600 mg of rifabutin daily, and 15 mg of ethambutol per kilogram of body . . . http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The New England Journal of Medicine The New England Journal of Medicine

Uveitis and Pseudojaundice During a Regimen of Clarithromycin, Rifabutin, and Ethambutol

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References (1)

Publisher
The New England Journal of Medicine
Copyright
Copyright © 1994 Massachusetts Medical Society. All rights reserved.
ISSN
0028-4793
eISSN
1533-4406
DOI
10.1056/NEJM199402103300616
pmid
8284019
Publisher site
See Article on Publisher Site

Abstract

To the Editor: We report the occurrence of uveitis and pseudojaundice in patients with AIDS who were receiving the combination of clarithromycin, rifabutin, and ethambutol for the treatment of Mycobacterium avium complex bacteremia. We are conducting a prospective, randomized, multicenter study comparing two oral multidrug regimens for the treatment of M. avium complex bacteremia in adults with AIDS. As of November 5, 1993, 119 patients had entered this study, 59 of whom were assigned to receive a regimen consisting of 1000 mg of clarithromycin twice daily, 600 mg of rifabutin daily, and 15 mg of ethambutol per kilogram of body . . .

Journal

The New England Journal of MedicineThe New England Journal of Medicine

Published: Feb 10, 1994

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